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Protein

Interferon regulatory factor 2-binding protein-like

Gene

IRF2BPL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May contribute to the control of female reproductive function (By similarity). May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri715 – 762RING-type; degenerateAdd BLAST48

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Interferon regulatory factor 2-binding protein-like
Alternative name(s):
Enhanced at puberty protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IRF2BPL
Synonyms:C14orf4, EAP1, KIAA1865
ORF Names:My039
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000119669.4

Human Gene Nomenclature Database

More...
HGNCi
HGNC:14282 IRF2BPL

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611720 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H1B7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi715C → A: Loss of transcription activity. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
64207

Open Targets

More...
OpenTargetsi
ENSG00000119669

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25516

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IRF2BPL

Domain mapping of disease mutations (DMDM)

More...
DMDMi
34395562

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000564111 – 796Interferon regulatory factor 2-binding protein-likeAdd BLAST796

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei69PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki79Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei215PhosphoserineCombined sources1
Modified residuei519PhosphoserineCombined sources1
Modified residuei547PhosphoserineCombined sources1
Modified residuei639PhosphoserineCombined sources1
Modified residuei657PhosphoserineCombined sources1
Modified residuei658PhosphoserineCombined sources1
Modified residuei659PhosphoserineCombined sources1
Modified residuei662PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H1B7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H1B7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H1B7

PeptideAtlas

More...
PeptideAtlasi
Q9H1B7

PRoteomics IDEntifications database

More...
PRIDEi
Q9H1B7

ProteomicsDB human proteome resource

More...
ProteomicsDBi
80395

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H1B7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H1B7

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
Q9H1B7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in the heart, moderately in skeletal muscle and pancreas, and weakly in brain, kidney, liver, testis, thyroid gland and lymphocytes.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000119669 Expressed in 209 organ(s), highest expression level in layer of synovial tissue

CleanEx database of gene expression profiles

More...
CleanExi
HS_C14orf4

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H1B7 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA050862
HPA061333

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122101, 18 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9H1B7

Protein interaction database and analysis system

More...
IntActi
Q9H1B7, 4 interactors

Molecular INTeraction database

More...
MINTi
Q9H1B7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000238647

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1796
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9H1B7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H1B7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9H1B7

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili85 – 132Sequence analysisAdd BLAST48
Coiled coili335 – 371Sequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi88 – 102Poly-AlaAdd BLAST15
Compositional biasi103 – 127Poly-GlnAdd BLAST25
Compositional biasi153 – 164Poly-AlaAdd BLAST12
Compositional biasi174 – 296Gly/Pro-richAdd BLAST123
Compositional biasi596 – 623Pro-richAdd BLAST28

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IRF2BP family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri715 – 762RING-type; degenerateAdd BLAST48

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3579 Eukaryota
ENOG410Z1AW LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162596

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108364

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H1B7

KEGG Orthology (KO)

More...
KOi
K22383

Identification of Orthologs from Complete Genome Data

More...
OMAi
PSTHPGM

Database of Orthologous Groups

More...
OrthoDBi
EOG091G040R

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H1B7

TreeFam database of animal gene trees

More...
TreeFami
TF317075

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR022750 Interferon_reg_fac2-bd1_2_Znf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11261 IRF-2BP1_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9H1B7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAAQVSSSR RQSCYLCDLP RMPWAMIWDF SEPVCRGCVN YEGADRIEFV
60 70 80 90 100
IETARQLKRA HGCFQDGRSP GPPPPVGVKT VALSAKEAAA AAAAAAAAAA
110 120 130 140 150
AAQQQQQQQQ QQQQQQQQQQ QQQQQQQLNH VDGSSKPAVL AAPSGLERYG
160 170 180 190 200
LSAAAAAAAA AAAAVEQRSR FEYPPPPVSL GSSSHTARLP NGLGGPNGFP
210 220 230 240 250
KPTPEEGPPE LNRQSPNSSS AAASVASRRG THGGLVTGLP NPGGGGGPQL
260 270 280 290 300
TVPPNLLPQT LLNGPASAAV LPPPPPHALG SRGPPTPAPP GAPGGPACLG
310 320 330 340 350
GTPGVSATSS SASSSTSSSV AEVGVGAGGK RPGSVSSTDQ ERELKEKQRN
360 370 380 390 400
AEALAELSES LRNRAEEWAS KPKMVRDTLL TLAGCTPYEV RFKKDHSLLG
410 420 430 440 450
RVFAFDAVSK PGMDYELKLF IEYPTGSGNV YSSASGVAKQ MYQDCMKDFG
460 470 480 490 500
RGLSSGFKYL EYEKKHGSGD WRLLGDLLPE AVRFFKEGVP GADMLPQPYL
510 520 530 540 550
DASCPMLPTA LVSLSRAPSA PPGTGALPPA APSGRGAAAS LRKRKASPEP
560 570 580 590 600
PDSAEGALKL GEEQQRQQWM ANQSEALKLT MSAGGFAAPG HAAGGPPPPP
610 620 630 640 650
PPLGPHSNRT TPPESAPQNG PSPMAALMSV ADTLGTAHSP KDGSSVHSTT
660 670 680 690 700
ASARRNSSSP VSPASVPGQR RLASRNGDLN LQVAPPPPSA HPGMDQVHPQ
710 720 730 740 750
NIPDSPMANS GPLCCTICHE RLEDTHFVQC PSVPSHKFCF PCSRESIKAQ
760 770 780 790
GATGEVYCPS GEKCPLVGSN VPWAFMQGEI ATILAGDVKV KKERDP
Length:796
Mass (Da):82,659
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDCF7898F15AD6A37
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB47494 differs from that shown. Aberrant splicing.Curated

<p>This subsection of the ‘Sequence’ section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement_in_disease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

The poly-Gln region is polymorphic; the most frequent allele contained 24 Gln. Stretches of 20-31 Gln are observed in healthy individuals.1 Publication

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ277365 Genomic DNA Translation: CAC10539.1
AC007686 Genomic DNA No translation available.
AB058768 mRNA Translation: BAB47494.1 Sequence problems.
AL832320 mRNA Translation: CAD38615.1
AF063597 mRNA Translation: AAG43156.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9854.1

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7555

NCBI Reference Sequences

More...
RefSeqi
NP_078772.1, NM_024496.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.179260
Hs.745194

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000238647; ENSP00000238647; ENSG00000119669

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64207

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:64207

UCSC genome browser

More...
UCSCi
uc001xsy.4 human

Keywords - Coding sequence diversityi

Polymorphism, Triplet repeat expansion

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ277365 Genomic DNA Translation: CAC10539.1
AC007686 Genomic DNA No translation available.
AB058768 mRNA Translation: BAB47494.1 Sequence problems.
AL832320 mRNA Translation: CAD38615.1
AF063597 mRNA Translation: AAG43156.1
CCDSiCCDS9854.1
PIRiJC7555
RefSeqiNP_078772.1, NM_024496.3
UniGeneiHs.179260
Hs.745194

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2B9Gmodel-A708-771[»]
2CS3NMR-A705-784[»]
ProteinModelPortaliQ9H1B7
SMRiQ9H1B7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122101, 18 interactors
CORUMiQ9H1B7
IntActiQ9H1B7, 4 interactors
MINTiQ9H1B7
STRINGi9606.ENSP00000238647

PTM databases

iPTMnetiQ9H1B7
PhosphoSitePlusiQ9H1B7

Polymorphism and mutation databases

BioMutaiIRF2BPL
DMDMi34395562

Proteomic databases

EPDiQ9H1B7
MaxQBiQ9H1B7
PaxDbiQ9H1B7
PeptideAtlasiQ9H1B7
PRIDEiQ9H1B7
ProteomicsDBi80395

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000238647; ENSP00000238647; ENSG00000119669
GeneIDi64207
KEGGihsa:64207
UCSCiuc001xsy.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64207
DisGeNETi64207
EuPathDBiHostDB:ENSG00000119669.4

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IRF2BPL

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0011839
HGNCiHGNC:14282 IRF2BPL
HPAiHPA050862
HPA061333
MIMi611720 gene
neXtProtiNX_Q9H1B7
OpenTargetsiENSG00000119669
PharmGKBiPA25516

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3579 Eukaryota
ENOG410Z1AW LUCA
GeneTreeiENSGT00940000162596
HOVERGENiHBG108364
InParanoidiQ9H1B7
KOiK22383
OMAiPSTHPGM
OrthoDBiEOG091G040R
PhylomeDBiQ9H1B7
TreeFamiTF317075

Miscellaneous databases

EvolutionaryTraceiQ9H1B7

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
C14orf4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
64207
PMAP-CutDBiQ9H1B7

Protein Ontology

More...
PROi
PR:Q9H1B7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000119669 Expressed in 209 organ(s), highest expression level in layer of synovial tissue
CleanExiHS_C14orf4
GenevisibleiQ9H1B7 HS

Family and domain databases

InterProiView protein in InterPro
IPR022750 Interferon_reg_fac2-bd1_2_Znf
PfamiView protein in Pfam
PF11261 IRF-2BP1_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiI2BPL_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H1B7
Secondary accession number(s): Q8NDQ2, Q96JG2, Q9H3I7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: March 1, 2001
Last modified: December 5, 2018
This is version 144 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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