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UniProtKB - Q9H169 (STMN4_HUMAN)

Entry version 155 (23 Feb 2022)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
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Protein

Stathmin-4

Gene

STMN4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Exhibits microtubule-destabilizing activity.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • tubulin binding Source: GO_Central
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H169

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q9H169

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Stathmin-4
Alternative name(s):
Stathmin-like protein B3
Short name:
RB3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:STMN4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:16078, STMN4

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H169

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000015592

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Golgi apparatus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		81551

Open Targets

More...OpenTargetsi		ENSG00000015592

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA38089

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H169, Tbio

Chemistry databases

Drug and drug target database

More...DrugBanki		DB07574, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
DB01206, Lomustine

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		STMN4

Domain mapping of disease mutations (DMDM)

More...DMDMi		17368936

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001824061 – 189Stathmin-4Add BLAST189

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi20S-palmitoyl cysteineBy similarity1
Lipidationi22S-palmitoyl cysteineBy similarity1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei90PhosphoserineBy similarity1

Keywords - PTMi

Lipoprotein, Palmitate, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H169

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H169

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H169

PeptideAtlas

More...PeptideAtlasi		Q9H169

PRoteomics IDEntifications database

More...PRIDEi		Q9H169

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		34108
6479
80368 [Q9H169-1]
80369 [Q9H169-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H169

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H169

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000015592, Expressed in C1 segment of cervical spinal cord and 157 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H169, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H169, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000015592, Group enriched (brain, choroid plexus)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		123515, 32 interactors

Protein interaction database and analysis system

More...IntActi		Q9H169, 28 interactors

Molecular INTeraction database

More...MINTi		Q9H169

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H169, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1189
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9H169

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini48 – 189SLDPROSITE-ProRule annotationAdd BLAST142

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni168 – 189DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili90 – 188Sequence analysisAdd BLAST99

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the stathmin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT01030000234597

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_102026_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H169

Identification of Orthologs from Complete Genome Data

More...OMAi		TSMPHRR

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H169

TreeFam database of animal gene trees

More...TreeFami		TF326935

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR028834, Stathmin-4
IPR030514, Stathmin_CS
IPR000956, Stathmin_fam
IPR036002, Stathmin_sf

The PANTHER Classification System

More...PANTHERi		PTHR10104, PTHR10104, 1 hit
PTHR10104:SF6, PTHR10104:SF6, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00836, Stathmin, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002285, Stathmin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00345, STATHMIN

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF101494, SSF101494, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00563, STATHMIN_1, 1 hit
PS01041, STATHMIN_2, 1 hit
PS51663, STATHMIN_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H169-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTLAAYKEKM KELPLVSLFC SCFLADPLNK SSYKYEADTV DLNWCVISDM 
        60         70         80         90        100
EVIELNKCTS GQSFEVILKP PSFDGVPEFN ASLPRRRDPS LEEIQKKLEA 
       110        120        130        140        150
AEERRKYQEA ELLKHLAEKR EHEREVIQKA IEENNNFIKM AKEKLAQKME 
       160        170        180 
SNKENREAHL AAMLERLQEK DKHAEEVRKN KELKEEASR
Length:189
Mass (Da):22,071
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i861BBD533D3849AC
GO
Isoform 2 (identifier: Q9H169-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     36-36: E → EGWCGRQCRRKDESQRKDSADWRERRAQ

Show »
Length:216
Mass (Da):25,418
Checksum:i9B9FCE70A39F20B0
GO
Isoform 3 (identifier: Q9H169-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-9: Missing.
     171-188: DKHAEEVRKNKELKEEAS → EPPAA

Show »
Length:167
Mass (Da):19,378
Checksum:i3EE89D84248BC91A
GO
Isoform 4 (identifier: Q9H169-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     36-36: E → EGWCGRQCRRKDESQRKDSADWRERRAQ
     171-188: DKHAEEVRKNKELKEEAS → EPPAA

Show »
Length:203
Mass (Da):23,761
Checksum:i237ED0D212AE12F4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7EVN3E7EVN3_HUMAN
Stathmin-4
STMN4
258Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIR6E5RIR6_HUMAN
Stathmin-4
STMN4
231Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti11K → M in BAH12575 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0552791 – 9Missing in isoform 3. 1 Publication9
Alternative sequenceiVSP_00627936E → EGWCGRQCRRKDESQRKDSA DWRERRAQ in isoform 2 and isoform 4. 2 Publications1
Alternative sequenceiVSP_055280171 – 188DKHAE…KEEAS → EPPAA in isoform 3 and isoform 4. 1 PublicationAdd BLAST18

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AJ303455 mRNA Translation: CAC22254.1
AL136568 mRNA Translation: CAB66503.1
AK295329 mRNA Translation: BAH12033.1
AK297415 mRNA Translation: BAH12575.1
AC090150 Genomic DNA No translation available.
CH471080 Genomic DNA Translation: EAW63562.1
CH471080 Genomic DNA Translation: EAW63563.1
CH471080 Genomic DNA Translation: EAW63565.1
CH471080 Genomic DNA Translation: EAW63567.1
BC011520 mRNA Translation: AAH11520.1
BC111001 mRNA Translation: AAI11002.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS6055.1 [Q9H169-2]
CCDS64851.1 [Q9H169-3]
CCDS64852.1 [Q9H169-1]
CCDS64854.1 [Q9H169-4]

NCBI Reference Sequences

More...RefSeqi		NP_001269982.1, NM_001283053.1 [Q9H169-4]
NP_001269983.1, NM_001283054.1 [Q9H169-1]
NP_001269984.1, NM_001283055.1 [Q9H169-3]
NP_110422.2, NM_030795.3 [Q9H169-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000265770; ENSP00000265770; ENSG00000015592
ENST00000350889; ENSP00000342538; ENSG00000015592 [Q9H169-2]
ENST00000519997; ENSP00000428474; ENSG00000015592 [Q9H169-3]
ENST00000523048; ENSP00000428428; ENSG00000015592 [Q9H169-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		81551

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:81551

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000350889.9; ENSP00000342538.4; NM_030795.4; NP_110422.2 [Q9H169-2]

UCSC genome browser

More...UCSCi		uc003xfj.5, human [Q9H169-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ303455 mRNA Translation: CAC22254.1
AL136568 mRNA Translation: CAB66503.1
AK295329 mRNA Translation: BAH12033.1
AK297415 mRNA Translation: BAH12575.1
AC090150 Genomic DNA No translation available.
CH471080 Genomic DNA Translation: EAW63562.1
CH471080 Genomic DNA Translation: EAW63563.1
CH471080 Genomic DNA Translation: EAW63565.1
CH471080 Genomic DNA Translation: EAW63567.1
BC011520 mRNA Translation: AAH11520.1
BC111001 mRNA Translation: AAI11002.1
CCDSiCCDS6055.1 [Q9H169-2]
CCDS64851.1 [Q9H169-3]
CCDS64852.1 [Q9H169-1]
CCDS64854.1 [Q9H169-4]
RefSeqiNP_001269982.1, NM_001283053.1 [Q9H169-4]
NP_001269983.1, NM_001283054.1 [Q9H169-1]
NP_001269984.1, NM_001283055.1 [Q9H169-3]
NP_110422.2, NM_030795.3 [Q9H169-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6BR1X-ray2.30E49-189[»]
6BRFX-ray2.50E49-189[»]
6BRYX-ray2.70E49-189[»]
6NNGX-ray2.40E49-189[»]
6O5MX-ray2.30E49-189[»]
6O5NX-ray3.00E49-189[»]
6O61X-ray2.60E49-189[»]
6PC4X-ray2.60E49-189[»]
7CPDX-ray2.51E1-189[»]
SMRiQ9H169
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi123515, 32 interactors
IntActiQ9H169, 28 interactors
MINTiQ9H169

Chemistry databases

DrugBankiDB07574, 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
DB01206, Lomustine

PTM databases

iPTMnetiQ9H169
PhosphoSitePlusiQ9H169

Genetic variation databases

BioMutaiSTMN4
DMDMi17368936

Proteomic databases

jPOSTiQ9H169
MassIVEiQ9H169
MaxQBiQ9H169
PeptideAtlasiQ9H169
PRIDEiQ9H169
ProteomicsDBi34108
6479
80368 [Q9H169-1]
80369 [Q9H169-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		10084, 161 antibodies from 23 providers

The DNASU plasmid repository

More...DNASUi		81551

Genome annotation databases

EnsembliENST00000265770; ENSP00000265770; ENSG00000015592
ENST00000350889; ENSP00000342538; ENSG00000015592 [Q9H169-2]
ENST00000519997; ENSP00000428474; ENSG00000015592 [Q9H169-3]
ENST00000523048; ENSP00000428428; ENSG00000015592 [Q9H169-4]
GeneIDi81551
KEGGihsa:81551
MANE-SelectiENST00000350889.9; ENSP00000342538.4; NM_030795.4; NP_110422.2 [Q9H169-2]
UCSCiuc003xfj.5, human [Q9H169-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		81551
DisGeNETi81551

GeneCards: human genes, protein and diseases

More...GeneCardsi		STMN4
HGNCiHGNC:16078, STMN4
HPAiENSG00000015592, Group enriched (brain, choroid plexus)
neXtProtiNX_Q9H169
OpenTargetsiENSG00000015592
PharmGKBiPA38089
VEuPathDBiHostDB:ENSG00000015592

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT01030000234597
HOGENOMiCLU_102026_0_1_1
InParanoidiQ9H169
OMAiTSMPHRR
PhylomeDBiQ9H169
TreeFamiTF326935

Enzyme and pathway databases

PathwayCommonsiQ9H169
SignaLinkiQ9H169

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		81551, 5 hits in 1037 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		81551
PharosiQ9H169, Tbio

Protein Ontology

More...PROi		PR:Q9H169
RNActiQ9H169, protein

Gene expression databases

BgeeiENSG00000015592, Expressed in C1 segment of cervical spinal cord and 157 other tissues
ExpressionAtlasiQ9H169, baseline and differential
GenevisibleiQ9H169, HS

Family and domain databases

InterProiView protein in InterPro
IPR028834, Stathmin-4
IPR030514, Stathmin_CS
IPR000956, Stathmin_fam
IPR036002, Stathmin_sf
PANTHERiPTHR10104, PTHR10104, 1 hit
PTHR10104:SF6, PTHR10104:SF6, 1 hit
PfamiView protein in Pfam
PF00836, Stathmin, 1 hit
PIRSFiPIRSF002285, Stathmin, 1 hit
PRINTSiPR00345, STATHMIN
SUPFAMiSSF101494, SSF101494, 1 hit
PROSITEiView protein in PROSITE
PS00563, STATHMIN_1, 1 hit
PS01041, STATHMIN_2, 1 hit
PS51663, STATHMIN_3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSTMN4_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H169
Secondary accession number(s): B7Z2Z7
, B7Z4I9, D3DSS8, D3DSS9, G5EA16, Q2TAB9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: March 1, 2001
Last modified: February 23, 2022
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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