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Protein

RNA-binding protein 38

Gene

RBM38

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.2 Publications
(Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication.1 Publication

Caution

It is uncertain whether Met-1 or Met-24 is the initiator.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • mRNA 3'-UTR binding Source: UniProtKB
  • mRNA binding Source: UniProtKB
  • RNA binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processCell cycle, Differentiation, mRNA processing, mRNA splicing

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q9H0Z9

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA-binding protein 38
Alternative name(s):
CLL-associated antigen KW-5
HSRNASEB
RNA-binding motif protein 38
RNA-binding region-containing protein 1
ssDNA-binding protein SEB4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RBM38
Synonyms:RNPC1, SEB4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000132819.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15818 RBM38

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612428 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H0Z9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
55544

Open Targets

More...
OpenTargetsi
ENSG00000132819

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34449

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RBM38

Domain mapping of disease mutations (DMDM)

More...
DMDMi
215273895

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000818121 – 239RNA-binding protein 38Add BLAST239

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H0Z9

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H0Z9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H0Z9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H0Z9

PeptideAtlas

More...
PeptideAtlasi
Q9H0Z9

PRoteomics IDEntifications database

More...
PRIDEi
Q9H0Z9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
80346
80347 [Q9H0Z9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H0Z9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H0Z9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By p53/TP53 family. Directly induced by p53/TP53, TP63/p63 and TP73/p73.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000132819 Expressed in 223 organ(s), highest expression level in lower esophagus

CleanEx database of gene expression profiles

More...
CleanExi
HS_RBM38

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H0Z9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H0Z9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB017036

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120710, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H0Z9, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000348538

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1239
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQDNMR-A24-126[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9H0Z9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H0Z9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9H0Z9

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 111RRMPROSITE-ProRule annotationAdd BLAST78

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RBM38 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0149 Eukaryota
ENOG4111PGT LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158489

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108399

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H0Z9

Identification of Orthologs from Complete Genome Data

More...
OMAi
FLHYAPQ

Database of Orthologous Groups

More...
OrthoDBi
1579773at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H0Z9

TreeFam database of animal gene trees

More...
TreeFami
TF314235

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H0Z9-1) [UniParc]FASTAAdd to basket
Also known as: RNPC1a

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLQPAPCAP SAGFPRPLAA PGAMHGSQKD TTFTKIFVGG LPYHTTDASL
60 70 80 90 100
RKYFEGFGDI EEAVVITDRQ TGKSRGYGFV TMADRAAAER ACKDPNPIID
110 120 130 140 150
GRKANVNLAY LGAKPRSLQT GFAIGVQQLH PTLIQRTYGL TPHYIYPPAI
160 170 180 190 200
VQPSVVIPAA PVPSLSSPYI EYTPASPAYA QYPPATYDQY PYAASPATAA
210 220 230
SFVGYSYPAA VPQALSAAAP AGTTFVQYQA PQLQPDRMQ
Length:239
Mass (Da):25,498
Last modified:November 25, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF20038A92C980757
GO
Isoform 2 (identifier: Q9H0Z9-2) [UniParc]FASTAAdd to basket
Also known as: RNPC1b

The sequence of this isoform differs from the canonical sequence as follows:
     122-239: Missing.

Show »
Length:121
Mass (Da):12,914
Checksum:i7A4B2F4C1B35CB0B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6VZ39F6VZ39_HUMAN
RNA-binding protein 38
RBM38
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PSF1E9PSF1_HUMAN
RNA-binding protein 38
RBM38
77Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A6NG75A6NG75_HUMAN
RNA-binding protein 38
RBM38
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH18711 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence AAL99924 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAA53064 differs from that shown. Chimeric cDNA.Curated
The sequence EAW75522 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti15P → S in CAA53063 (Ref. 4) Curated1
Sequence conflicti23 – 25AMH → VMY in CAA53063 (Ref. 4) Curated3
Sequence conflicti25H → Y in CAA53063 (Ref. 4) Curated1
Sequence conflicti30D → G in CAA53063 (Ref. 4) Curated1
Sequence conflicti116 – 117RS → WC in CAA53063 (Ref. 4) Curated2
Sequence conflicti116 – 117RS → WC in CAA53064 (Ref. 4) Curated2

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_015225178A → V1 PublicationCorresponds to variant dbSNP:rs1065288Ensembl.1
Natural variantiVAR_015226200A → D1 PublicationCorresponds to variant dbSNP:rs1065289Ensembl.1
Natural variantiVAR_015227212P → H1 PublicationCorresponds to variant dbSNP:rs1065290Ensembl.1
Natural variantiVAR_059823226V → L. Corresponds to variant dbSNP:rs16980970Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_035881122 – 239Missing in isoform 2. CuratedAdd BLAST118

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF432218 mRNA Translation: AAL99924.1 Different initiation.
AL109955 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75522.1 Sequence problems.
X75314 mRNA Translation: CAA53063.1
X75315 mRNA Translation: CAA53064.1 Sequence problems.
BC018711 mRNA Translation: AAH18711.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46617.1 [Q9H0Z9-1]
CCDS46618.1 [Q9H0Z9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001278709.1, NM_001291780.1
NP_059965.2, NM_017495.5 [Q9H0Z9-1]
NP_906270.1, NM_183425.2 [Q9H0Z9-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.236361

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000356208; ENSP00000348538; ENSG00000132819 [Q9H0Z9-1]
ENST00000440234; ENSP00000407848; ENSG00000132819 [Q9H0Z9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55544

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55544

UCSC genome browser

More...
UCSCi
uc010zzj.3 human [Q9H0Z9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF432218 mRNA Translation: AAL99924.1 Different initiation.
AL109955 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75522.1 Sequence problems.
X75314 mRNA Translation: CAA53063.1
X75315 mRNA Translation: CAA53064.1 Sequence problems.
BC018711 mRNA Translation: AAH18711.1 Different initiation.
CCDSiCCDS46617.1 [Q9H0Z9-1]
CCDS46618.1 [Q9H0Z9-2]
RefSeqiNP_001278709.1, NM_001291780.1
NP_059965.2, NM_017495.5 [Q9H0Z9-1]
NP_906270.1, NM_183425.2 [Q9H0Z9-2]
UniGeneiHs.236361

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQDNMR-A24-126[»]
ProteinModelPortaliQ9H0Z9
SMRiQ9H0Z9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120710, 8 interactors
IntActiQ9H0Z9, 8 interactors
STRINGi9606.ENSP00000348538

PTM databases

iPTMnetiQ9H0Z9
PhosphoSitePlusiQ9H0Z9

Polymorphism and mutation databases

BioMutaiRBM38
DMDMi215273895

Proteomic databases

EPDiQ9H0Z9
jPOSTiQ9H0Z9
MaxQBiQ9H0Z9
PaxDbiQ9H0Z9
PeptideAtlasiQ9H0Z9
PRIDEiQ9H0Z9
ProteomicsDBi80346
80347 [Q9H0Z9-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55544
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000356208; ENSP00000348538; ENSG00000132819 [Q9H0Z9-1]
ENST00000440234; ENSP00000407848; ENSG00000132819 [Q9H0Z9-2]
GeneIDi55544
KEGGihsa:55544
UCSCiuc010zzj.3 human [Q9H0Z9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55544
DisGeNETi55544
EuPathDBiHostDB:ENSG00000132819.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RBM38

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0015939
HGNCiHGNC:15818 RBM38
HPAiCAB017036
MIMi612428 gene
neXtProtiNX_Q9H0Z9
OpenTargetsiENSG00000132819
PharmGKBiPA34449

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0149 Eukaryota
ENOG4111PGT LUCA
GeneTreeiENSGT00940000158489
HOVERGENiHBG108399
InParanoidiQ9H0Z9
OMAiFLHYAPQ
OrthoDBi1579773at2759
PhylomeDBiQ9H0Z9
TreeFamiTF314235

Enzyme and pathway databases

SIGNORiQ9H0Z9

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
RBM38 human
EvolutionaryTraceiQ9H0Z9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55544

Protein Ontology

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PROi
PR:Q9H0Z9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000132819 Expressed in 223 organ(s), highest expression level in lower esophagus
CleanExiHS_RBM38
ExpressionAtlasiQ9H0Z9 baseline and differential
GenevisibleiQ9H0Z9 HS

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRBM38_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H0Z9
Secondary accession number(s): A6NDK1
, A6NMU6, Q15350, Q15351, Q9BYK3, Q9BYK4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: November 25, 2008
Last modified: January 16, 2019
This is version 151 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
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