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UniProtKB - Q9H0X4 (F234A_HUMAN)

Entry version 154 (10 Feb 2021)
Sequence version 1 (01 Mar 2001)
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Protein

Protein FAM234A

Gene

FAM234A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q9H0X4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM234A
Alternative name(s):
Protein ITFG3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM234AImported
Synonyms:C16orf9, ITFG3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:14163, FAM234A

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q9H0X4

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000167930.15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 49CytoplasmicSequence analysisAdd BLAST49
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei50 – 70Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini71 – 552ExtracellularSequence analysisAdd BLAST482

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		83986

Open Targets

More...OpenTargetsi		ENSG00000167930

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA25564

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q9H0X4, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		FAM234A

Domain mapping of disease mutations (DMDM)

More...DMDMi		74733531

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002479931 – 552Protein FAM234AAdd BLAST552

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei21PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi116N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi314N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi389N-linked (GlcNAc...) asparagine2 Publications1
Glycosylationi473N-linked (GlcNAc...) asparagine1 Publication1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9H0X4

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9H0X4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q9H0X4

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9H0X4

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9H0X4

PeptideAtlas

More...PeptideAtlasi		Q9H0X4

PRoteomics IDEntifications database

More...PRIDEi		Q9H0X4

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		80339 [Q9H0X4-1]
80340 [Q9H0X4-2]

PTM databases

GlyConnect protein glycosylation platform

More...GlyConnecti		1662, 1 N-Linked glycan (1 site)

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		Q9H0X4, 5 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9H0X4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9H0X4

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q9H0X4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000167930, Expressed in C1 segment of cervical spinal cord and 206 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9H0X4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9H0X4, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000167930, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		123837, 20 interactors

Protein interaction database and analysis system

More...IntActi		Q9H0X4, 10 interactors

Molecular INTeraction database

More...MINTi		Q9H0X4

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000382814

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9H0X4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM234 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502R0CE, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00530000063694

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_036490_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9H0X4

Identification of Orthologs from Complete Genome Data

More...OMAi		PCTFVAA

Database of Orthologous Groups

More...OrthoDBi		294858at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9H0X4

TreeFam database of animal gene trees

More...TreeFami		TF327203

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011047, Quinoprotein_ADH-like_supfam

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50998, SSF50998, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 12 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H0X4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLDHKDLEAE IHPLKNEERK SQENLGNPSK NEDNVKSAPP QSRLSRCRAA 
        60         70         80         90        100
AFFLSLFLCL FVVFVVSFVI PCPDRPASQR MWRIDYSAAV IYDFLAVDDI 
       110        120        130        140        150
NGDRIQDVLF LYKNTNSSNN FSRSCVDEGF SSPCTFAAAV SGANGSTLWE 
       160        170        180        190        200
RPVAQDVALV ECAVPQPRGS EAPSACILVG RPSSFIAVNL FTGETLWNHS 
       210        220        230        240        250
SSFSGNASIL SPLLQVPDVD GDGAPDLLVL TQEREEVSGH LYSGSTGHQI 
       260        270        280        290        300
GLRGSLGVDG ESGFLLHVTR TGAHYILFPC ASSLCGCSVK GLYEKVTGSG 
       310        320        330        340        350
GPFKSDPHWE SMLNATTRRM LSHSSGAVRY LMHVPGNAGA DVLLVGSEAF 
       360        370        380        390        400
VLLDGQELTP RWTPKAAHVL RKPIFGRYKP DTLAVAVENG TGTDRQILFL 
       410        420        430        440        450
DLGTGAVLCS LALPSLPGGP LSASLPTADH RSAFFFWGLH ELGSTSETET 
       460        470        480        490        500
GEARHSLYMF HPTLPRVLLE LANVSTHIVA FDAVLFEPSR HAAYILLTGP 
       510        520        530        540        550
ADSEAPGLVS VIKHKVRDLV PSSRVVRLGE GGPDSDQAIR DRFSRLRYQS 

EA
Length:552
Mass (Da):59,660
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAC81CB184EC3B043
GO
Isoform 2 (identifier: Q9H0X4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     516-540: VRDLVPSSRVVRLGEGGPDSDQAIR → AHTGRQRRGSWTGQSSRRDLHVRVL
     541-552: Missing.

Show »
Length:540
Mass (Da):58,388
Checksum:i4031F2348BA6637E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B4DGG1B4DGG1_HUMAN
Protein FAM234A
FAM234A
531Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J3Y6C9J3Y6_HUMAN
Protein FAM234A
FAM234A
233Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9IYB9C9IYB9_HUMAN
Protein FAM234A
FAM234A
236Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JJN3C9JJN3_HUMAN
Protein FAM234A
FAM234A
87Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9K0C5C9K0C5_HUMAN
Protein FAM234A
FAM234A
242Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JTF7C9JTF7_HUMAN
Protein FAM234A
FAM234A
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J8V3C9J8V3_HUMAN
Protein FAM234A
FAM234A
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JP72C9JP72_HUMAN
Protein FAM234A
FAM234A
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JR71C9JR71_HUMAN
Protein FAM234A
FAM234A
102Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J1M4C9J1M4_HUMAN
Protein FAM234A
FAM234A
50Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK61220 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti20K → E in BAB71374 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_020121516 – 540VRDLV…DQAIR → AHTGRQRRGSWTGQSSRRDL HVRVL in isoform 2. 1 PublicationAdd BLAST25
Alternative sequenceiVSP_020122541 – 552Missing in isoform 2. 1 PublicationAdd BLAST12

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL136542 mRNA Translation: CAB66477.1
AK057165 mRNA Translation: BAB71374.1
AE006462 Genomic DNA Translation: AAK61220.1 Sequence problems.
CH471112 Genomic DNA Translation: EAW85846.1
CH471112 Genomic DNA Translation: EAW85847.1
BC010521 mRNA Translation: AAH10521.1
BC013047 mRNA Translation: AAH13047.1
BC032112 mRNA Translation: AAH32112.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10402.1 [Q9H0X4-1]

NCBI Reference Sequences

More...RefSeqi		NP_001271426.1, NM_001284497.1 [Q9H0X4-1]
NP_114428.1, NM_032039.3 [Q9H0X4-1]
XP_005255679.1, XM_005255622.1 [Q9H0X4-1]
XP_011520993.1, XM_011522691.1 [Q9H0X4-1]
XP_011520994.1, XM_011522692.1 [Q9H0X4-1]
XP_016879249.1, XM_017023760.1 [Q9H0X4-1]
XP_016879250.1, XM_017023761.1 [Q9H0X4-1]
XP_016879251.1, XM_017023762.1 [Q9H0X4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000301678; ENSP00000301678; ENSG00000167930 [Q9H0X4-1]
ENST00000301679; ENSP00000301679; ENSG00000167930 [Q9H0X4-2]
ENST00000399932; ENSP00000382814; ENSG00000167930 [Q9H0X4-1]
ENST00000654053; ENSP00000499447; ENSG00000167930 [Q9H0X4-2]
ENST00000659283; ENSP00000499694; ENSG00000167930 [Q9H0X4-2]
ENST00000666018; ENSP00000499687; ENSG00000167930 [Q9H0X4-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		83986

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:83986

UCSC genome browser

More...UCSCi		uc002cgf.4, human [Q9H0X4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136542 mRNA Translation: CAB66477.1
AK057165 mRNA Translation: BAB71374.1
AE006462 Genomic DNA Translation: AAK61220.1 Sequence problems.
CH471112 Genomic DNA Translation: EAW85846.1
CH471112 Genomic DNA Translation: EAW85847.1
BC010521 mRNA Translation: AAH10521.1
BC013047 mRNA Translation: AAH13047.1
BC032112 mRNA Translation: AAH32112.1
CCDSiCCDS10402.1 [Q9H0X4-1]
RefSeqiNP_001271426.1, NM_001284497.1 [Q9H0X4-1]
NP_114428.1, NM_032039.3 [Q9H0X4-1]
XP_005255679.1, XM_005255622.1 [Q9H0X4-1]
XP_011520993.1, XM_011522691.1 [Q9H0X4-1]
XP_011520994.1, XM_011522692.1 [Q9H0X4-1]
XP_016879249.1, XM_017023760.1 [Q9H0X4-1]
XP_016879250.1, XM_017023761.1 [Q9H0X4-1]
XP_016879251.1, XM_017023762.1 [Q9H0X4-1]

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi123837, 20 interactors
IntActiQ9H0X4, 10 interactors
MINTiQ9H0X4
STRINGi9606.ENSP00000382814

PTM databases

GlyConnecti1662, 1 N-Linked glycan (1 site)
GlyGeniQ9H0X4, 5 sites
iPTMnetiQ9H0X4
PhosphoSitePlusiQ9H0X4
SwissPalmiQ9H0X4

Genetic variation databases

BioMutaiFAM234A
DMDMi74733531

Proteomic databases

EPDiQ9H0X4
jPOSTiQ9H0X4
MassIVEiQ9H0X4
MaxQBiQ9H0X4
PaxDbiQ9H0X4
PeptideAtlasiQ9H0X4
PRIDEiQ9H0X4
ProteomicsDBi80339 [Q9H0X4-1]
80340 [Q9H0X4-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2603, 140 antibodies

The DNASU plasmid repository

More...DNASUi		83986

Genome annotation databases

EnsembliENST00000301678; ENSP00000301678; ENSG00000167930 [Q9H0X4-1]
ENST00000301679; ENSP00000301679; ENSG00000167930 [Q9H0X4-2]
ENST00000399932; ENSP00000382814; ENSG00000167930 [Q9H0X4-1]
ENST00000654053; ENSP00000499447; ENSG00000167930 [Q9H0X4-2]
ENST00000659283; ENSP00000499694; ENSG00000167930 [Q9H0X4-2]
ENST00000666018; ENSP00000499687; ENSG00000167930 [Q9H0X4-2]
GeneIDi83986
KEGGihsa:83986
UCSCiuc002cgf.4, human [Q9H0X4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		83986
DisGeNETi83986

GeneCards: human genes, protein and diseases

More...GeneCardsi		FAM234A
HGNCiHGNC:14163, FAM234A
HPAiENSG00000167930, Low tissue specificity
neXtProtiNX_Q9H0X4
OpenTargetsiENSG00000167930
PharmGKBiPA25564
VEuPathDBiHostDB:ENSG00000167930.15

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502R0CE, Eukaryota
GeneTreeiENSGT00530000063694
HOGENOMiCLU_036490_0_0_1
InParanoidiQ9H0X4
OMAiPCTFVAA
OrthoDBi294858at2759
PhylomeDBiQ9H0X4
TreeFamiTF327203

Enzyme and pathway databases

PathwayCommonsiQ9H0X4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		83986, 5 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		FAM234A, human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ITFG3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		83986
PharosiQ9H0X4, Tdark

Protein Ontology

More...PROi		PR:Q9H0X4
RNActiQ9H0X4, protein

Gene expression databases

BgeeiENSG00000167930, Expressed in C1 segment of cervical spinal cord and 206 other tissues
ExpressionAtlasiQ9H0X4, baseline and differential
GenevisibleiQ9H0X4, HS

Family and domain databases

InterProiView protein in InterPro
IPR011047, Quinoprotein_ADH-like_supfam
SUPFAMiSSF50998, SSF50998, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF234A_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H0X4
Secondary accession number(s): D3DU45
, Q7L416, Q96FR1, Q96MC7, Q96S30
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: March 1, 2001
Last modified: February 10, 2021
This is version 154 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
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