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Entry version 125 (18 Sep 2019)
Sequence version 2 (17 Apr 2007)
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Protein

Transmembrane protein 168

Gene

TMEM168

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 168
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM168
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25826 TMEM168

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9H0V1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei36 – 56HelicalSequence analysisAdd BLAST21
Transmembranei63 – 83HelicalSequence analysisAdd BLAST21
Transmembranei89 – 109HelicalSequence analysisAdd BLAST21
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Transmembranei199 – 219HelicalSequence analysisAdd BLAST21
Transmembranei223 – 243HelicalSequence analysisAdd BLAST21
Transmembranei265 – 285HelicalSequence analysisAdd BLAST21
Transmembranei293 – 313HelicalSequence analysisAdd BLAST21
Transmembranei352 – 372HelicalSequence analysisAdd BLAST21
Transmembranei380 – 400HelicalSequence analysisAdd BLAST21
Transmembranei646 – 666HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000146802

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147357253

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM168

Domain mapping of disease mutations (DMDM)

More...
DMDMi
145566969

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002846301 – 697Transmembrane protein 168Add BLAST697

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi111N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi533N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi598N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9H0V1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9H0V1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9H0V1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9H0V1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9H0V1

PeptideAtlas

More...
PeptideAtlasi
Q9H0V1

PRoteomics IDEntifications database

More...
PRIDEi
Q9H0V1

ProteomicsDB human proteome resource

More...
ProteomicsDBi
3886
80328 [Q9H0V1-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9H0V1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9H0V1

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9H0V1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000146802 Expressed in 223 organ(s), highest expression level in placenta

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9H0V1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9H0V1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA020389

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122167, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q9H0V1, 4 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000323068

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9H0V1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM168 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IF3C Eukaryota
ENOG410Y9XB LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005941

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000069876

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9H0V1

Identification of Orthologs from Complete Genome Data

More...
OMAi
THRVDNN

Database of Orthologous Groups

More...
OrthoDBi
619817at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9H0V1

TreeFam database of animal gene trees

More...
TreeFami
TF328518

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029713 TMEM168

The PANTHER Classification System

More...
PANTHERi
PTHR14437 PTHR14437, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9H0V1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MCKSLRYCFS HCLYLAMTRL EEVNREVNMH SSVRYLGYLA RINLLVAICL
60 70 80 90 100
GLYVRWEKTA NSLILVIFIL GLFVLGIASI LYYYFSMEAA SLSLSNLWFG
110 120 130 140 150
FLLGLLCFLD NSSFKNDVKE ESTKYLLLTS IVLRILCSLV ERISGYVRHR
160 170 180 190 200
PTLLTTVEFL ELVGFAIAST TMLVEKSLSV ILLVVALAML IIDLRMKSFL
210 220 230 240 250
AIPNLVIFAV LLFFSSLETP KNPIAFACFF ICLITDPFLD IYFSGLSVTE
260 270 280 290 300
RWKPFLYRGR ICRRLSVVFA GMIELTFFIL SAFKLRDTHL WYFVIPGFSI
310 320 330 340 350
FGIFWMICHI IFLLTLWGFH TKLNDCHKVY FTHRTDYNSL DRIMASKGMR
360 370 380 390 400
HFCLISEQLV FFSLLATAIL GAVSWQPTNG IFLSMFLIVL PLESMAHGLF
410 420 430 440 450
HELGNCLGGT SVGYAIVIPT NFCSPDGQPT LLPPEHVQEL NLRSTGMLNA
460 470 480 490 500
IQRFFAYHMI ETYGCDYSTS GLSFDTLHSK LKAFLELRTV DGPRHDTYIL
510 520 530 540 550
YYSGHTHGTG EWALAGGDTL RLDTLIEWWR EKNGSFCSRL IIVLDSENST
560 570 580 590 600
PWVKEVRKIN DQYIAVQGAE LIKTVDIEEA DPPQLGDFTK DWVEYNCNSS
610 620 630 640 650
NNICWTEKGR TVKAVYGVSK RWSDYTLHLP TGSDVAKHWM LHFPRITYPL
660 670 680 690
VHLANWLCGL NLFWICKTCF RCLKRLKMSW FLPTVLDTGQ GFKLVKS
Length:697
Mass (Da):79,755
Last modified:April 17, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF23471DFF43D28E0
GO
Isoform 2 (identifier: Q9H0V1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-384: Missing.

Note: No experimental confirmation available.
Show »
Length:313
Mass (Da):35,634
Checksum:i89497F2E7E34F35F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C268H7C268_HUMAN
Transmembrane protein 168
TMEM168
258Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9IZT1C9IZT1_HUMAN
Transmembrane protein 168
TMEM168
112Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JVE9C9JVE9_HUMAN
Transmembrane protein 168
TMEM168
124Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAQ96836 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB14624 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti305W → R in CAB66561 (PubMed:11230166).Curated1
Sequence conflicti333H → P in BAB14624 (PubMed:14702039).Curated1
Sequence conflicti574T → A in BAB14624 (PubMed:14702039).Curated1
Sequence conflicti600S → C in CAB66561 (PubMed:11230166).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0568461 – 384Missing in isoform 2. 1 PublicationAdd BLAST384

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL136626 mRNA Translation: CAB66561.1
AK023638 mRNA Translation: BAB14624.1 Different initiation.
AK293311 mRNA Translation: BAG56831.1
AK314460 mRNA Translation: BAG37068.1
AC079621 Genomic DNA Translation: AAQ96836.1 Different initiation.
CH236947 Genomic DNA Translation: EAL24373.1
CH471070 Genomic DNA Translation: EAW83470.1
CH471070 Genomic DNA Translation: EAW83471.1
BC030804 mRNA Translation: AAH30804.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5757.1 [Q9H0V1-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001274426.1, NM_001287497.1 [Q9H0V1-1]
NP_071929.3, NM_022484.5 [Q9H0V1-1]
XP_016868012.1, XM_017012523.1 [Q9H0V1-1]
XP_016868014.1, XM_017012525.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000312814; ENSP00000323068; ENSG00000146802 [Q9H0V1-1]
ENST00000447395; ENSP00000410307; ENSG00000146802 [Q9H0V1-2]
ENST00000454074; ENSP00000390696; ENSG00000146802 [Q9H0V1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64418

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:64418

UCSC genome browser

More...
UCSCi
uc003vgn.5 human [Q9H0V1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136626 mRNA Translation: CAB66561.1
AK023638 mRNA Translation: BAB14624.1 Different initiation.
AK293311 mRNA Translation: BAG56831.1
AK314460 mRNA Translation: BAG37068.1
AC079621 Genomic DNA Translation: AAQ96836.1 Different initiation.
CH236947 Genomic DNA Translation: EAL24373.1
CH471070 Genomic DNA Translation: EAW83470.1
CH471070 Genomic DNA Translation: EAW83471.1
BC030804 mRNA Translation: AAH30804.2
CCDSiCCDS5757.1 [Q9H0V1-1]
RefSeqiNP_001274426.1, NM_001287497.1 [Q9H0V1-1]
NP_071929.3, NM_022484.5 [Q9H0V1-1]
XP_016868012.1, XM_017012523.1 [Q9H0V1-1]
XP_016868014.1, XM_017012525.1

3D structure databases

SMRiQ9H0V1
ModBaseiSearch...

Protein-protein interaction databases

BioGridi122167, 5 interactors
IntActiQ9H0V1, 4 interactors
STRINGi9606.ENSP00000323068

PTM databases

iPTMnetiQ9H0V1
PhosphoSitePlusiQ9H0V1
SwissPalmiQ9H0V1

Polymorphism and mutation databases

BioMutaiTMEM168
DMDMi145566969

Proteomic databases

EPDiQ9H0V1
jPOSTiQ9H0V1
MassIVEiQ9H0V1
MaxQBiQ9H0V1
PaxDbiQ9H0V1
PeptideAtlasiQ9H0V1
PRIDEiQ9H0V1
ProteomicsDBi3886
80328 [Q9H0V1-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
64418
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000312814; ENSP00000323068; ENSG00000146802 [Q9H0V1-1]
ENST00000447395; ENSP00000410307; ENSG00000146802 [Q9H0V1-2]
ENST00000454074; ENSP00000390696; ENSG00000146802 [Q9H0V1-1]
GeneIDi64418
KEGGihsa:64418
UCSCiuc003vgn.5 human [Q9H0V1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64418

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM168
HGNCiHGNC:25826 TMEM168
HPAiHPA020389
neXtProtiNX_Q9H0V1
OpenTargetsiENSG00000146802
PharmGKBiPA147357253

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IF3C Eukaryota
ENOG410Y9XB LUCA
GeneTreeiENSGT00390000005941
HOGENOMiHOG000069876
InParanoidiQ9H0V1
OMAiTHRVDNN
OrthoDBi619817at2759
PhylomeDBiQ9H0V1
TreeFamiTF328518

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
64418

Pharos

More...
Pharosi
Q9H0V1

Protein Ontology

More...
PROi
PR:Q9H0V1

Gene expression databases

BgeeiENSG00000146802 Expressed in 223 organ(s), highest expression level in placenta
ExpressionAtlasiQ9H0V1 baseline and differential
GenevisibleiQ9H0V1 HS

Family and domain databases

InterProiView protein in InterPro
IPR029713 TMEM168
PANTHERiPTHR14437 PTHR14437, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM168_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9H0V1
Secondary accession number(s): A4D0T9
, B4DDS0, Q8NEK4, Q9H8J2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 17, 2007
Last sequence update: April 17, 2007
Last modified: September 18, 2019
This is version 125 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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