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Entry version 131 (16 Oct 2019)
Sequence version 1 (01 Mar 2001)
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Protein

Neurensin-2

Gene

NRSN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in maintenance and/or transport of vesicles.

Caution

It is uncertain whether Met-1 or Met-2 is the initiator.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

Transport Classification Database

More...
TCDBi
8.A.122.1.2 the vesicular membrane neurensin/tmem74 (neurensin/tmem74) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neurensin-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NRSN2
Synonyms:C20orf98
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:16229 NRSN2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610666 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q9GZP1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei66 – 86HelicalSequence analysisAdd BLAST21
Transmembranei122 – 142HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
80023

Open Targets

More...
OpenTargetsi
ENSG00000125841

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25805

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q9GZP1

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
NRSN2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
25008324

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002216751 – 204Neurensin-2Add BLAST204

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q9GZP1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9GZP1

PeptideAtlas

More...
PeptideAtlasi
Q9GZP1

PRoteomics IDEntifications database

More...
PRIDEi
Q9GZP1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
80104

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9GZP1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9GZP1

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9GZP1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000125841 Expressed in 139 organ(s), highest expression level in right frontal lobe

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9GZP1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9GZP1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA015967

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123077, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q9GZP1, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000371728

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the VMP family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHGJ Eukaryota
ENOG4111B0E LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063877

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231873

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9GZP1

Identification of Orthologs from Complete Genome Data

More...
OMAi
ICLFWAM

Database of Orthologous Groups

More...
OrthoDBi
1530336at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9GZP1

TreeFam database of animal gene trees

More...
TreeFami
TF332090

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024883 Neurensin
IPR029701 Nrsn2

The PANTHER Classification System

More...
PANTHERi
PTHR14796 PTHR14796, 1 hit
PTHR14796:SF5 PTHR14796:SF5, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q9GZP1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMPSCNRSCS CSRGPSVEDG KWYGVRSYLH LFYEDCAGTA LSDDPEGPPV
60 70 80 90 100
LCPRRPWPSL CWKISLSSGT LLLLLGVAAL TTGYAVPPKL EGIGEGEFLV
110 120 130 140 150
LDQRAADYNQ ALGTCRLAGT ALCVAAGVLL AICLFWAMIG WLSQDTKAEP
160 170 180 190 200
LDPEADSHVE VFGDEPEQQL SPIFRNASGQ SWFSPPASPF GQSSVQTIQP

KRDS
Length:204
Mass (Da):21,983
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD20FAAE67C0FF16D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
V9GYV8V9GYV8_HUMAN
Neurensin-2
NRSN2
113Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GZ28V9GZ28_HUMAN
Neurensin-2
NRSN2
116Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GYN1V9GYN1_HUMAN
Neurensin-2
NRSN2
161Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GY99V9GY99_HUMAN
Neurensin-2
NRSN2
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
V9GYY0V9GYY0_HUMAN
Neurensin-2
NRSN2
82Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WVS5A0A087WVS5_HUMAN
Neurensin-2
NRSN2
65Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05373841L → V. Corresponds to variant dbSNP:rs11556643Ensembl.1
Natural variantiVAR_05373965S → C. Corresponds to variant dbSNP:rs17762763Ensembl.1
Natural variantiVAR_062158160E → Q. Corresponds to variant dbSNP:rs35731713Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL136915 mRNA Translation: CAB66849.1
AK026982 mRNA Translation: BAB15613.1
AK290527 mRNA Translation: BAF83216.1
CR533441 mRNA Translation: CAG38472.1
AL034548 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10680.1
BC001963 mRNA Translation: AAH01963.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12996.1

NCBI Reference Sequences

More...
RefSeqi
NP_001310608.1, NM_001323679.1
NP_001310609.1, NM_001323680.1
NP_001310610.1, NM_001323681.1
NP_001310611.1, NM_001323682.1
NP_001310612.1, NM_001323683.1
NP_001310613.1, NM_001323684.1
NP_001310614.1, NM_001323685.1
NP_079234.1, NM_024958.2
XP_006723693.1, XM_006723630.3
XP_011527662.1, XM_011529360.1
XP_011527664.1, XM_011529362.2
XP_011527665.1, XM_011529363.2
XP_016883562.1, XM_017028073.1
XP_016883563.1, XM_017028074.1
XP_016883564.1, XM_017028075.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000382285; ENSP00000371722; ENSG00000125841
ENST00000382291; ENSP00000371728; ENSG00000125841
ENST00000621012; ENSP00000482706; ENSG00000125841

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80023

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:80023

UCSC genome browser

More...
UCSCi
uc002wdi.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136915 mRNA Translation: CAB66849.1
AK026982 mRNA Translation: BAB15613.1
AK290527 mRNA Translation: BAF83216.1
CR533441 mRNA Translation: CAG38472.1
AL034548 Genomic DNA No translation available.
CH471133 Genomic DNA Translation: EAX10680.1
BC001963 mRNA Translation: AAH01963.1
CCDSiCCDS12996.1
RefSeqiNP_001310608.1, NM_001323679.1
NP_001310609.1, NM_001323680.1
NP_001310610.1, NM_001323681.1
NP_001310611.1, NM_001323682.1
NP_001310612.1, NM_001323683.1
NP_001310613.1, NM_001323684.1
NP_001310614.1, NM_001323685.1
NP_079234.1, NM_024958.2
XP_006723693.1, XM_006723630.3
XP_011527662.1, XM_011529360.1
XP_011527664.1, XM_011529362.2
XP_011527665.1, XM_011529363.2
XP_016883562.1, XM_017028073.1
XP_016883563.1, XM_017028074.1
XP_016883564.1, XM_017028075.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi123077, 5 interactors
IntActiQ9GZP1, 8 interactors
STRINGi9606.ENSP00000371728

Protein family/group databases

TCDBi8.A.122.1.2 the vesicular membrane neurensin/tmem74 (neurensin/tmem74) family

PTM databases

iPTMnetiQ9GZP1
PhosphoSitePlusiQ9GZP1
SwissPalmiQ9GZP1

Polymorphism and mutation databases

BioMutaiNRSN2
DMDMi25008324

Proteomic databases

MassIVEiQ9GZP1
PaxDbiQ9GZP1
PeptideAtlasiQ9GZP1
PRIDEiQ9GZP1
ProteomicsDBi80104

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
80023

Genome annotation databases

EnsembliENST00000382285; ENSP00000371722; ENSG00000125841
ENST00000382291; ENSP00000371728; ENSG00000125841
ENST00000621012; ENSP00000482706; ENSG00000125841
GeneIDi80023
KEGGihsa:80023
UCSCiuc002wdi.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80023
DisGeNETi80023

GeneCards: human genes, protein and diseases

More...
GeneCardsi
NRSN2
HGNCiHGNC:16229 NRSN2
HPAiHPA015967
MIMi610666 gene
neXtProtiNX_Q9GZP1
OpenTargetsiENSG00000125841
PharmGKBiPA25805

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IHGJ Eukaryota
ENOG4111B0E LUCA
GeneTreeiENSGT00530000063877
HOGENOMiHOG000231873
InParanoidiQ9GZP1
OMAiICLFWAM
OrthoDBi1530336at2759
PhylomeDBiQ9GZP1
TreeFamiTF332090

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
NRSN2 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
NRSN2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80023
PharosiQ9GZP1

Protein Ontology

More...
PROi
PR:Q9GZP1

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000125841 Expressed in 139 organ(s), highest expression level in right frontal lobe
ExpressionAtlasiQ9GZP1 baseline and differential
GenevisibleiQ9GZP1 HS

Family and domain databases

InterProiView protein in InterPro
IPR024883 Neurensin
IPR029701 Nrsn2
PANTHERiPTHR14796 PTHR14796, 1 hit
PTHR14796:SF5 PTHR14796:SF5, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNRSN2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9GZP1
Secondary accession number(s): A8K3B2, Q6FII5, Q9NUD3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: March 1, 2001
Last modified: October 16, 2019
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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