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Entry version 122 (12 Aug 2020)
Sequence version 3 (19 Oct 2011)
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Protein

Protein Skeletor, isoforms D/E

Gene

Skeletor

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Provides structural support to stabilize and organize the microtubule spindle during mitosis (within embryonic somatic cells) and meiosis (within spermatocytes). The role in mitosis regulation depends on the Ran pathway.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Meiosis, Mitosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein Skeletor, isoforms D/E
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CG43161
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0262717, Skeletor

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Cytoplasm, Cytoskeleton, Microtubule, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 28Sequence analysisAdd BLAST28
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000009777829 – 1503Protein Skeletor, isoforms D/EAdd BLAST1475

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9GPJ1

PRoteomics IDEntifications database

More...
PRIDEi
Q9GPJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Isoform D is expressed during embryonic development.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0262717, Expressed in capitellum (Drosophila) and 27 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9GPJ1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9GPJ1, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with Chro and Mtor as part of a macromolecular complex forming the spindle matrix. Chro colocalizes with Skeletor on the chromosomes at interphase and on spindle during metaphase.

2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
534156, 1 interactor

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0296946

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 143DM13 1PROSITE-ProRule annotationAdd BLAST110
Domaini151 – 258DM13 2PROSITE-ProRule annotationAdd BLAST108
Domaini287 – 419DOMONPROSITE-ProRule annotationAdd BLAST133

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi831 – 1036Pro-richAdd BLAST206
Compositional biasi904 – 932His-richAdd BLAST29
Compositional biasi1452 – 1485Ser-richAdd BLAST34

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4731, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004063_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9GPJ1

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9GPJ1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019545, DM13_domain
IPR005018, DOMON_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10517, DM13, 2 hits
PF03351, DOMON, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00686, DM13, 2 hits
SM00664, DoH, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51549, DM13, 2 hits
PS50836, DOMON, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform E (identifier: Q9GPJ1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLAMKDKPWL LLFGLLAALS CLASFGDAAY PYYGTKIGAL TRLHHGVSGD
60 70 80 90 100
VYAVDSRTIF IKKFNYDGEA PAAYFYVGNT ARPSNEGAAR LRDERGGTAS
110 120 130 140 150
LTRRYRNKDV TLSLPEGKTL RDIKWFSVWC DEFAVNFGDV SIPPNLDFPR
160 170 180 190 200
PQKISALRGV HGVSSDNIVI VDAQTLLVPN FSYDGEAPDA KFWVGRGQRP
210 220 230 240 250
TSDGLRIPDE NGKENPLRRY ERKTIVLTLP EDLTIFDIGH FGVWCEAFTV
260 270 280 290 300
DFGHVRLPEG LNVPPSLKML GISPQSKLNC EVLYDDLAFE VRWAVAGESI
310 320 330 340 350
VVQLVAKLEP NHYMSFGISP NKNISQMIGA DAVVAWVDPQ TGNGFATDYF
360 370 380 390 400
LEGKAQCSGG RGACPDTKIS EKTNSIRLLN AAMVNGYSIV TYQRSLAATD
410 420 430 440 450
RLDLPISITG AESVVWAIGP LNDYQEVSFH TFYNKHLHQI EFGRQPKWNC
460 470 480 490 500
PLPEGARGNS NSSEQEDSAP AAQSSTGGAG YPPAGRPNVE PDEEFYENRA
510 520 530 540 550
EALHRQPPQR RQETAIITQR RPVPTPKPVN SNGAWDIPAI QCHEPEDGVF
560 570 580 590 600
YAQMGPTGGK HGYPAITGHV GWGISWYING LLIPEIHVVR GKTYTFVVEG
610 620 630 640 650
GNNPDIPAKY HPFYISDDPV GGYEHKREEE KKAVRIYAGV HRSRSGQVTP
660 670 680 690 700
TGVGRLCNWT PDVEGPPADD YQSFGAYQRT LTLKCDAGEP GVITWKPDRN
710 720 730 740 750
TPDTVYYHCF THRYLGWKIH VHDSCDSEAG GLKGAASERH EIRLPAKATV
760 770 780 790 800
AEPAPVHEDY AGEASVRHET KVSANDNFLL KHQTDLIKNH NMNGTPPKLS
810 820 830 840 850
FEITKSSEIT KLISDGIRAA EALEESLLRN PNLNPNHPNQ NPIPNPHQKP
860 870 880 890 900
NVTPTEISSR PEILLGETHA HTLNASPSAS AYPSPSATLP SANLKLPILA
910 920 930 940 950
AGPHLIHHPP HLHRLHHQPQ HAPHPHVHLH HHNLTANLPA LAQKTIGLSE
960 970 980 990 1000
FLRPPQNAPL FHPVKLPGRR PFPAPIKKVP ASRPILPQQH PHLHPHPQQH
1010 1020 1030 1040 1050
PVLLQQQPSL IVSHYRKPIP GLLKPFVKEK PFPLQPLAAS VLLLGQPTEL
1060 1070 1080 1090 1100
GGLNNKGERL KIKGKPKIPV PYVDLEPQGS LQNTAIFNQP GGKGKGDQKP
1110 1120 1130 1140 1150
KASSVSISTT PIPLVKRPTV KEPSQEEIAS MRPAVNQGFK PDTVIVESGF
1160 1170 1180 1190 1200
KPIVRTDGTG VQLPKEIIDQ VAHRREDPGT EIDEVMETDT LFLAAQQGGS
1210 1220 1230 1240 1250
ETQSFEPMFI PSPLDSTNAT KVLRVNVKEV SPTASALRLP SAALEHALPS
1260 1270 1280 1290 1300
ASELIKPTLD ELFAEDLNEE ELEMEPMPVA DDVESLEETT KKDAVTTTIN
1310 1320 1330 1340 1350
IPRNTTKKPD PDLLEDLFGP DEEELYADEL ELDMDDRVAA AAERIDTYYL
1360 1370 1380 1390 1400
PPDNRKIPDT RVPSGALYTF DGKSVVDSSL VLPPKLDAPD NANVHQRHAQ
1410 1420 1430 1440 1450
YGLTPLEQLV RTTPQFGVYR GELPQEFRGT EPQPVSEYSH PAPFSRTTPV
1460 1470 1480 1490 1500
FSSSSGSTIY PYSSSTGAST STVSSSASSP LSSSSLRPIS TKLQLLKPEG

RRA
Length:1,503
Mass (Da):165,043
Last modified:October 19, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB5321298E35819E5
GO
Isoform D (identifier: Q9GPJ1-2) [UniParc]FASTAAdd to basket
Also known as: ORF2

The sequence of this isoform differs from the canonical sequence as follows:
     1-791: Missing.

Show »
Length:712
Mass (Da):77,685
Checksum:i28B234EE6F5ADF82
GO
Isoform B (identifier: Q9VGY6-2) [UniParc]FASTAAdd to basket
Also known as: ORF1a
The sequence of this isoform can be found in the external entry Q9VGY6.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:289
Mass (Da):32,122
GO
Isoform C (identifier: Q9VGY6-1) [UniParc]FASTAAdd to basket
Also known as: ORF1b
The sequence of this isoform can be found in the external entry Q9VGY6.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:784
Mass (Da):86,562
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4K6P5A0A0B4K6P5_DROME
Skeletor, isoform E
Skeletor 2Ab3, CG14681, CG14682, CG31261, CG32922
1,503Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG46059 differs from that shown. Intron retention.Curated
The sequence AAL39254 differs from that shown. Intron retention.Curated
The sequence AAO41539 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0418981 – 791Missing in isoform D. 2 PublicationsAdd BLAST791

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF321289 mRNA Translation: AAG46059.1 Sequence problems.
AE014297 Genomic DNA Translation: AAO41539.1 Sequence problems.
AY069109 mRNA Translation: AAL39254.1 Sequence problems.

NCBI Reference Sequences

More...
RefSeqi
NP_001027173.2, NM_001032002.2 [Q9GPJ1-2]
NP_001247027.1, NM_001260098.1 [Q9GPJ1-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0305665; FBpp0296945; FBgn0262717 [Q9GPJ1-2]
FBtr0305666; FBpp0296946; FBgn0262717 [Q9GPJ1-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3772559

UCSC genome browser

More...
UCSCi
CG33676-RA, d. melanogaster [Q9GPJ1-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF321289 mRNA Translation: AAG46059.1 Sequence problems.
AE014297 Genomic DNA Translation: AAO41539.1 Sequence problems.
AY069109 mRNA Translation: AAL39254.1 Sequence problems.
RefSeqiNP_001027173.2, NM_001032002.2 [Q9GPJ1-2]
NP_001247027.1, NM_001260098.1 [Q9GPJ1-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi534156, 1 interactor
STRINGi7227.FBpp0296946

Proteomic databases

PaxDbiQ9GPJ1
PRIDEiQ9GPJ1

Genome annotation databases

EnsemblMetazoaiFBtr0305665; FBpp0296945; FBgn0262717 [Q9GPJ1-2]
FBtr0305666; FBpp0296946; FBgn0262717 [Q9GPJ1-1]
GeneIDi3772559
UCSCiCG33676-RA, d. melanogaster [Q9GPJ1-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3772559
FlyBaseiFBgn0262717, Skeletor

Phylogenomic databases

eggNOGiKOG4731, Eukaryota
HOGENOMiCLU_004063_0_0_1
InParanoidiQ9GPJ1
PhylomeDBiQ9GPJ1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
3772559, 0 hits in 1 CRISPR screen

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
3772559

Gene expression databases

BgeeiFBgn0262717, Expressed in capitellum (Drosophila) and 27 other tissues
ExpressionAtlasiQ9GPJ1, baseline and differential
GenevisibleiQ9GPJ1, DM

Family and domain databases

InterProiView protein in InterPro
IPR019545, DM13_domain
IPR005018, DOMON_domain
PfamiView protein in Pfam
PF10517, DM13, 2 hits
PF03351, DOMON, 1 hit
SMARTiView protein in SMART
SM00686, DM13, 2 hits
SM00664, DoH, 1 hit
PROSITEiView protein in PROSITE
PS51549, DM13, 2 hits
PS50836, DOMON, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSKEL2_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9GPJ1
Secondary accession number(s): Q8T0R5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 19, 2011
Last modified: August 12, 2020
This is version 122 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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