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Entry version 113 (07 Apr 2021)
Sequence version 1 (01 Mar 2001)
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Protein

Probable beta-1,4-xylosyltransferase IRX10

Gene

IRX10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the synthesis of the hemicellulose glucuronoxylan, a major component of secondary cell walls. Probably involved in the elongation of glucuronoxylan xylosyl backbone, especially in the formation of GlcUA side chain of xylans.

3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • 1,4-beta-D-xylan synthase activity Source: TAIR
  • glucuronoxylan glucuronosyltransferase activity Source: TAIR

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT1G27440-MONOMER

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT47, Glycosyltransferase Family 47

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable beta-1,4-xylosyltransferase IRX10 (EC:2.4.2.-)
Alternative name(s):
Glucuronoxylan glucuronosyltransferase 1
Short name:
AtGUT1
Glucuronoxylan glucuronosyltransferase 2
Protein IRREGULAR XYLEM 10
Xylan xylosyltransferase IRX10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IRX10
Synonyms:GUT1, GUT2
Ordered Locus Names:At1g27440
ORF Names:F17L21.23
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G27440

The Arabidopsis Information Resource

More...
TAIRi
locus:2016004, AT1G27440

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1 – 21Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini22 – 412LumenalSequence analysisAdd BLAST391

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Moderate IRX phenotype. Slight reduction of secondary wall thickness and xylan content in cell wall (PubMed:15980264, PubMed:18980662). Specific loss of the GlcUA side chain in xylans. Slightly short inflorescence and reduced fertility (PubMed:18980649).3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004075761 – 412Probable beta-1,4-xylosyltransferase IRX10Add BLAST412

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi139N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi400N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FZJ1

PRoteomics IDEntifications database

More...
PRIDEi
Q9FZJ1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
247050

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Limited to xylem cells. Expressed in the root tip, xylem cells of roots, and in the vasculature of roots, cotyledons and leaves.2 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In flowers, restricted to anthers.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9FZJ1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9FZJ1, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
24870, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q9FZJ1, 9 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT1G27440.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9FZJ1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 47 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1021, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_039682_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FZJ1

Identification of Orthologs from Complete Genome Data

More...
OMAi
NINVAHI

Database of Orthologous Groups

More...
OrthoDBi
789556at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FZJ1

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004263, Exostosin
IPR040911, Exostosin_GT47

The PANTHER Classification System

More...
PANTHERi
PTHR11062, PTHR11062, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03016, Exostosin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9FZJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKIHSCLSAI LLFLFFSASS AKQNVRTERI SGSAGDVLED DPVGKLKVYV
60 70 80 90 100
YELPSKYNKK LLQKDPRCLT HMFAAEIFMH RFLLSSPVRT RNPDEADWFY
110 120 130 140 150
TPIYPTCDLT PTGLPLPFKS PRMMRSSIQL ISSNWPYWNR TEGADHFFVV
160 170 180 190 200
PHDFGACFHY QEEKAIERGI LPLLQRATLV QTFGQRNHVC LDEGSITIPP
210 220 230 240 250
FAPPQKMQAH FIPPDIPRSI FVYFRGLFYD VNNDPEGGYY ARGARAAVWE
260 270 280 290 300
NFKNNPLFDI STDHPTTYYE DMQRAIFCLC PLGWAPWSPR LVEAVVFGCI
310 320 330 340 350
PVIIADDIVL PFADAIPWEE IGVFVAEKDV PELDTILTSI PTEVILRKQR
360 370 380 390 400
LLANPSMKRA MLFPQPAQPG DAFHQILNGL ARKLPHDKSI YLKTGEKALN
410
WTAGPVADLK PW
Length:412
Mass (Da):46,843
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37F694D052F80D39
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KJ138982 mRNA Translation: AHL38922.1
AC004557 Genomic DNA Translation: AAF99743.1
CP002684 Genomic DNA Translation: AEE30830.1
BT022053 mRNA Translation: AAY25465.1
BT025555 mRNA Translation: ABF58973.1

NCBI Reference Sequences

More...
RefSeqi
NP_174064.1, NM_102508.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G27440.1; AT1G27440.1; AT1G27440

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
839635

Gramene; a comparative resource for plants

More...
Gramenei
AT1G27440.1; AT1G27440.1; AT1G27440

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G27440

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

JBEI Glycosyltransferase (GT) Collection
CAZY, the Carbohydrate Active enZYmes database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ138982 mRNA Translation: AHL38922.1
AC004557 Genomic DNA Translation: AAF99743.1
CP002684 Genomic DNA Translation: AEE30830.1
BT022053 mRNA Translation: AAY25465.1
BT025555 mRNA Translation: ABF58973.1
RefSeqiNP_174064.1, NM_102508.3

3D structure databases

SMRiQ9FZJ1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi24870, 9 interactors
IntActiQ9FZJ1, 9 interactors
STRINGi3702.AT1G27440.1

Protein family/group databases

CAZyiGT47, Glycosyltransferase Family 47

Proteomic databases

PaxDbiQ9FZJ1
PRIDEiQ9FZJ1
ProteomicsDBi247050

Genome annotation databases

EnsemblPlantsiAT1G27440.1; AT1G27440.1; AT1G27440
GeneIDi839635
GrameneiAT1G27440.1; AT1G27440.1; AT1G27440
KEGGiath:AT1G27440

Organism-specific databases

AraportiAT1G27440
TAIRilocus:2016004, AT1G27440

Phylogenomic databases

eggNOGiKOG1021, Eukaryota
HOGENOMiCLU_039682_1_0_1
InParanoidiQ9FZJ1
OMAiNINVAHI
OrthoDBi789556at2759
PhylomeDBiQ9FZJ1

Enzyme and pathway databases

BioCyciARA:AT1G27440-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9FZJ1

Gene expression databases

ExpressionAtlasiQ9FZJ1, baseline and differential
GenevisibleiQ9FZJ1, AT

Family and domain databases

InterProiView protein in InterPro
IPR004263, Exostosin
IPR040911, Exostosin_GT47
PANTHERiPTHR11062, PTHR11062, 1 hit
PfamiView protein in Pfam
PF03016, Exostosin, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIRX10_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FZJ1
Secondary accession number(s): W8PVA7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: March 1, 2001
Last modified: April 7, 2021
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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