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Entry version 96 (11 Dec 2019)
Sequence version 1 (01 Mar 2001)
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Protein

Scarecrow-like protein 8

Gene

SCL8

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcription factor involved in plant development.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Scarecrow-like protein 8
Short name:
AtSCL8
Alternative name(s):
GRAS family protein 30
Short name:
AtGRAS-30
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCL8
Ordered Locus Names:At5g52510
ORF Names:T4M5.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G52510

The Arabidopsis Information Resource

More...
TAIRi
locus:2184625 AT5G52510

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003508521 – 640Scarecrow-like protein 8Add BLAST640

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FYR7

PRoteomics IDEntifications database

More...
PRIDEi
Q9FYR7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in seedlings, roots, leaves and siliques.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9FYR7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9FYR7 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT5G52510.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9FYR7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini256 – 640GRASPROSITE-ProRule annotationAdd BLAST385

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni263 – 317Leucine repeat I (LRI)PROSITE-ProRule annotationAdd BLAST55
Regioni333 – 408VHIIDPROSITE-ProRule annotationAdd BLAST76
Regioni428 – 460Leucine repeat II (LRII)PROSITE-ProRule annotationAdd BLAST33
Regioni470 – 563PFYREPROSITE-ProRule annotationAdd BLAST94
Regioni566 – 640SAWPROSITE-ProRule annotationAdd BLAST75

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi368 – 372VHIIDPROSITE-ProRule annotation5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi4 – 66Gly-richAdd BLAST63
Compositional biasi74 – 91Gln-richAdd BLAST18
Compositional biasi145 – 150Poly-Gln6
Compositional biasi242 – 255Ser-richAdd BLAST14

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GRAS family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFRC Eukaryota
ENOG410YA1H LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000239354

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FYR7

Identification of Orthologs from Complete Genome Data

More...
OMAi
RFGMAGL

Database of Orthologous Groups

More...
OrthoDBi
548298at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FYR7

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030013 Scarecrow-like_8
IPR005202 TF_GRAS

The PANTHER Classification System

More...
PANTHERi
PTHR31636:SF221 PTHR31636:SF221, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03514 GRAS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50985 GRAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9FYR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESGFSGGGG GSDFYGGGGG RSIPGGPGTV INVGNNNPQT TYRNQIPGIF
60 70 80 90 100
FDQIGNRVAG GNGFSGKRTL ADFQAAQQHQ QQQQQQPFYS QAALNAFLSR
110 120 130 140 150
SVKPRNYQNF QSPSPMIDLT SVNDMSLFGG SGSSQRYGLP VPRSQTQQQQ
160 170 180 190 200
SDYGLFGGIR MGIGSGINNY PTLTGVPCIE PVQNRVHESE NMLNSLRELE
210 220 230 240 250
KQLLDDDDES GGDDDVSVIT NSNSDWIQNL VTPNPNPNPV LSFSPSSSSS
260 270 280 290 300
SSSPSTASTT TSVCSRQTVM EIATAIAEGK TEIATEILAR VSQTPNLERN
310 320 330 340 350
SEEKLVDFMV AALRSRIASP VTELYGKEHL ISTQLLYELS PCFKLGFEAA
360 370 380 390 400
NLAILDAADN NDGGMMIPHV IDFDIGEGGQ YVNLLRTLST RRNGKSQSQN
410 420 430 440 450
SPVVKITAVA NNVYGCLVDD GGEERLKAVG DLLSQLGDRL GISVSFNVVT
460 470 480 490 500
SLRLGDLNRE SLGCDPDETL AVNLAFKLYR VPDESVCTEN PRDELLRRVK
510 520 530 540 550
GLKPRVVTLV EQEMNSNTAP FLGRVSESCA CYGALLESVE STVPSTNSDR
560 570 580 590 600
AKVEEGIGRK LVNAVACEGI DRIERCEVFG KWRMRMSMAG FELMPLSEKI
610 620 630 640
AESMKSRGNR VHPGFTVKED NGGVCFGWMG RALTVASAWR
Length:640
Mass (Da):69,150
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC333A4855A739F9B
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAM20537 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti68 – 78RTLADFQAAQQ → KDFSRFSSGSE in AAD24408 (PubMed:10341448).CuratedAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP000378 Genomic DNA Translation: BAB10182.1
CP002688 Genomic DNA Translation: AED96223.1
AF036305 mRNA Translation: AAD24408.1
AY099686 mRNA Translation: AAM20537.1 Different initiation.
AY128868 mRNA Translation: AAM91268.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T51239

NCBI Reference Sequences

More...
RefSeqi
NP_200064.3, NM_124630.5

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G52510.1; AT5G52510.1; AT5G52510

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
835327

Gramene; a comparative resource for plants

More...
Gramenei
AT5G52510.1; AT5G52510.1; AT5G52510

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G52510

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000378 Genomic DNA Translation: BAB10182.1
CP002688 Genomic DNA Translation: AED96223.1
AF036305 mRNA Translation: AAD24408.1
AY099686 mRNA Translation: AAM20537.1 Different initiation.
AY128868 mRNA Translation: AAM91268.1
PIRiT51239
RefSeqiNP_200064.3, NM_124630.5

3D structure databases

SMRiQ9FYR7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G52510.1

Proteomic databases

PaxDbiQ9FYR7
PRIDEiQ9FYR7

Genome annotation databases

EnsemblPlantsiAT5G52510.1; AT5G52510.1; AT5G52510
GeneIDi835327
GrameneiAT5G52510.1; AT5G52510.1; AT5G52510
KEGGiath:AT5G52510

Organism-specific databases

AraportiAT5G52510
TAIRilocus:2184625 AT5G52510

Phylogenomic databases

eggNOGiENOG410IFRC Eukaryota
ENOG410YA1H LUCA
HOGENOMiHOG000239354
InParanoidiQ9FYR7
OMAiRFGMAGL
OrthoDBi548298at2759
PhylomeDBiQ9FYR7

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9FYR7

Gene expression databases

ExpressionAtlasiQ9FYR7 baseline and differential
GenevisibleiQ9FYR7 AT

Family and domain databases

InterProiView protein in InterPro
IPR030013 Scarecrow-like_8
IPR005202 TF_GRAS
PANTHERiPTHR31636:SF221 PTHR31636:SF221, 1 hit
PfamiView protein in Pfam
PF03514 GRAS, 1 hit
PROSITEiView protein in PROSITE
PS50985 GRAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCL8_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FYR7
Secondary accession number(s): Q8L553, Q9XE55
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: March 1, 2001
Last modified: December 11, 2019
This is version 96 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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