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Protein

ABC transporter B family member 25

Gene

ABCB25

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Metal transporter involved in the sequestration of aluminum into vacuoles, which is required for cellular detoxification of aluminum.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi415 – 422ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • aluminum ion transmembrane transport Source: UniProtKB
  • cellular aluminum ion homeostasis Source: UniProtKB
  • response to aluminum ion Source: UniProtKB

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-1369007 Mitochondrial ABC transporters

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 251 Publication
Short name:
ABC transporter ABCB.251 Publication
Short name:
OsABCB251 Publication
Alternative name(s):
Protein ALS1 homologCurated
Protein ALUMINUM SENSITIVE 11 Publication
Short name:
OsALS11 Publication
Gene namesi
Name:ABCB251 Publication
Synonyms:ALS11 Publication
Ordered Locus Names:Os03g0755100Imported, LOC_Os03g54790Imported
ORF Names:OSJNBb0081K01.19Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei100 – 120HelicalSequence analysisAdd BLAST21
Transmembranei191 – 211HelicalSequence analysisAdd BLAST21
Transmembranei284 – 304HelicalSequence analysisAdd BLAST21
Transmembranei320 – 340HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Vacuole

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth conditions, but mutant plants are hypersensitive to aluminum.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004055751 – 641ABC transporter B family member 25Add BLAST641

Proteomic databases

PaxDbiQ9FNU2

Expressioni

Tissue specificityi

Expressed in primary roots ans lateral roots.1 Publication

Inductioni

Induced by aluminum in roots.1 Publication

Gene expression databases

ExpressionAtlasiQ9FNU2 differential
GenevisibleiQ9FNU2 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os03g54790.1

Structurei

3D structure databases

ProteinModelPortaliQ9FNU2
SMRiQ9FNU2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 346ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST292
Domaini380 – 617ABC transporterPROSITE-ProRule annotationAdd BLAST238

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0058 Eukaryota
COG1132 LUCA
InParanoidiQ9FNU2
OMAiMLIDPIS
OrthoDBiEOG09360534

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9FNU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKNLRIKTG NRAPLLAQGE TSRALSDLEE GSNVQPENVG FCRVIKLARH
60 70 80 90 100
DAGKLVIATM ALLVASLSNI LVPKYGGKII DIVSRDVRRP EDKAQALDDV
110 120 130 140 150
TGTILYIVII VVTGSVCTAL RAWLFNSASE RVVARLRKDL FSHLVNQEIA
160 170 180 190 200
FFDVTRTGEL LSRLSEDTQI IKNAATTNLS EALRNITTTS IGLGFMFATS
210 220 230 240 250
WKLTLLALVI VPVISIAVRK FGRFLRELSH QTQAAAAVAS SIAEESFGAI
260 270 280 290 300
RTVRSFAQES HEVLRYGEKV DETLKLGLKQ AKVVGMFSGG LNAASTLSVV
310 320 330 340 350
IVVIYGANLT INGYMTTGSL TSFILYSLTV GSSVSALSGL YTTVMKASGA
360 370 380 390 400
SRRVFQLLDR VSSMANSGDR CPTNENDGEV ELDDVWFAYP SRPSHMILKG
410 420 430 440 450
ITLKLTPGSK VALVGPSGGG KTTIANLIER FYDPLKGRIL LNGVPLPEIS
460 470 480 490 500
HQFLHRKVSI VSQEPVLFNC SIEENIAYGL EGKASSADVE NAAKMANAHN
510 520 530 540 550
FICSFPDQYK TVVGERGIRL SGGQKQRVAI ARALLMNPRV LLLDEATSAL
560 570 580 590 600
DAESEYLVQD AMDSLMKGRT VLVIAHRLST VKSADTVAVI SDGQIVESGT
610 620 630 640
HDELLSRDGI YTALVKRQLQ GPRFEGTSNA TAEIEPISNG Q
Length:641
Mass (Da):69,200
Last modified:March 1, 2001 - v1
Checksum:iF82D17EABADE0134
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY013245 Genomic DNA Translation: AAG45492.1
AB625451 mRNA Translation: BAM09409.1
AC120509 Genomic DNA Translation: AAR01687.1
DP000009 Genomic DNA Translation: ABF98942.1
AP008209 Genomic DNA Translation: BAF13225.1
AP014959 Genomic DNA Translation: BAS86444.1
AK066049 mRNA Translation: BAG89793.1

Genome annotation databases

EnsemblPlantsiOs03t0755100-01; Os03t0755100-01; Os03g0755100
GrameneiOs03t0755100-01; Os03t0755100-01; Os03g0755100

Similar proteinsi

Entry informationi

Entry nameiAB25B_ORYSJ
AccessioniPrimary (citable) accession number: Q9FNU2
Secondary accession number(s): I0IVW0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 1, 2001
Last modified: July 18, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

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