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Entry version 150 (13 Feb 2019)
Sequence version 1 (01 Mar 2001)
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Protein

WD repeat-containing protein 26 homolog

Gene

WDR26

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a component involved in the crosstalk regulation between light, hormone and abiotic stress response.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • response to abscisic acid Source: TAIR
  • response to auxin Source: TAIR
  • response to ethylene Source: TAIR
  • response to light stimulus Source: TAIR
  • response to osmotic stress Source: TAIR

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WD repeat-containing protein 26 homologCurated
Short name:
AtWDR261 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WDR261 Publication
Ordered Locus Names:At5g08560Imported
ORF Names:MAH20.12Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G08560

The Arabidopsis Information Resource

More...
TAIRi
locus:2159562 AT5G08560

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004420581 – 589WD repeat-containing protein 26 homologAdd BLAST589

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FNN2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9FNN2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in roots, leaves and flowers.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced by auxin, abscisic acid (ABA), ethylene, mannitol and salt stress. Down-regulated by dark.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RANBPM.1 Publication

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9FNN2, 4 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G08560.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q9FNN2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini64 – 96LisHPROSITE-ProRule annotationAdd BLAST33
Domaini97 – 154CTLHPROSITE-ProRule annotationAdd BLAST58
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati272 – 311WD 1Sequence analysisAdd BLAST40
Repeati317 – 358WD 2Sequence analysisAdd BLAST42
Repeati360 – 398WD 3Sequence analysisAdd BLAST39
Repeati401 – 440WD 4Sequence analysisAdd BLAST40
Repeati442 – 480WD 5Sequence analysisAdd BLAST39
Repeati484 – 526WD 6Sequence analysisAdd BLAST43
Repeati529 – 569WD 7Sequence analysisAdd BLAST41

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0293 Eukaryota
ENOG410XQ2U LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000160946

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FNN2

KEGG Orthology (KO)

More...
KOi
K22382

Identification of Orthologs from Complete Genome Data

More...
OMAi
APLRINT

Database of Orthologous Groups

More...
OrthoDBi
349428at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FNN2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006595 CTLH_C
IPR020472 G-protein_beta_WD-40_rep
IPR006594 LisH
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00400 WD40, 5 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00320 GPROTEINBRPT

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00668 CTLH, 1 hit
SM00667 LisH, 1 hit
SM00320 WD40, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978 SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50897 CTLH, 1 hit
PS50896 LISH, 1 hit
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9FNN2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVVEDTEPP LKRAKRLADE PNGFSANSSV RGSSVNSNSL GDLMARPLPS
60 70 80 90 100
QGDDETIGSK GVIRKSEFVR IITRALYSLG YDKTGAMLEE ESGISLHNST
110 120 130 140 150
IKLFLQQVKD GKWDQSVKTL HRIGFPDEKA VKAASFLLLE QKFLEFLKVE
160 170 180 190 200
KIADALRTLR NEMAPLRINT KRVHELASSL ISPSSFISHT TSTPGKESVN
210 220 230 240 250
SRSKVLEELQ TLLPASVIIP EKRLECLVEN SLHIQRDSCV FHNTLDSDLS
260 270 280 290 300
LYSDHQCGKH QIPSQTAQIL ESHTDEVWFL QFSHNGKYLA SSSKDQTAII
310 320 330 340 350
WEISADGHIS LKHTLVGHHK PVIAILWSPD DRQVLTCGAE EVIRRWDVDS
360 370 380 390 400
GDCVHMYEKG GISPISCGWY PDGQGIIAGM TDRSICMWDL DGREKECWKG
410 420 430 440 450
QRTQKVSDIA MTDDGKWLVS VCKDSVISLF DREATVERLI EEEDMITSFS
460 470 480 490 500
LSNDNKYILV NLLNQEIRLW NIEGDPKIVS RYKGHKRSRF IIRSCFGGYK
510 520 530 540 550
QAFIASGSED SQVYIWHRST GKLIVELPGH AGAVNCVSWS PTNLHMLASA
560 570 580
SDDGTIRIWG LDRINQQNQK KKLVQGSSSN GVIHRCNGN
Length:589
Mass (Da):65,830
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA4A46CFCA066184
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB006697 Genomic DNA Translation: BAB10005.1
CP002688 Genomic DNA Translation: AED91320.1
CP002688 Genomic DNA Translation: AED91321.1
CP002688 Genomic DNA Translation: ANM70934.1
AY054535 mRNA Translation: AAK96726.1
AY064639 mRNA Translation: AAL47352.1

NCBI Reference Sequences

More...
RefSeqi
NP_001078546.1, NM_001085077.1
NP_001318513.1, NM_001343018.1
NP_196473.1, NM_120942.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
At.20607

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G08560.1; AT5G08560.1; AT5G08560
AT5G08560.2; AT5G08560.2; AT5G08560
AT5G08560.3; AT5G08560.3; AT5G08560

Database of genes from NCBI RefSeq genomes

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GeneIDi
830756

Gramene; a comparative resource for plants

More...
Gramenei
AT5G08560.1; AT5G08560.1; AT5G08560
AT5G08560.2; AT5G08560.2; AT5G08560
AT5G08560.3; AT5G08560.3; AT5G08560

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G08560

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006697 Genomic DNA Translation: BAB10005.1
CP002688 Genomic DNA Translation: AED91320.1
CP002688 Genomic DNA Translation: AED91321.1
CP002688 Genomic DNA Translation: ANM70934.1
AY054535 mRNA Translation: AAK96726.1
AY064639 mRNA Translation: AAL47352.1
RefSeqiNP_001078546.1, NM_001085077.1
NP_001318513.1, NM_001343018.1
NP_196473.1, NM_120942.3
UniGeneiAt.20607

3D structure databases

ProteinModelPortaliQ9FNN2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9FNN2, 4 interactors
STRINGi3702.AT5G08560.1

PTM databases

iPTMnetiQ9FNN2

Proteomic databases

PaxDbiQ9FNN2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G08560.1; AT5G08560.1; AT5G08560
AT5G08560.2; AT5G08560.2; AT5G08560
AT5G08560.3; AT5G08560.3; AT5G08560
GeneIDi830756
GrameneiAT5G08560.1; AT5G08560.1; AT5G08560
AT5G08560.2; AT5G08560.2; AT5G08560
AT5G08560.3; AT5G08560.3; AT5G08560
KEGGiath:AT5G08560

Organism-specific databases

AraportiAT5G08560
TAIRilocus:2159562 AT5G08560

Phylogenomic databases

eggNOGiKOG0293 Eukaryota
ENOG410XQ2U LUCA
HOGENOMiHOG000160946
InParanoidiQ9FNN2
KOiK22382
OMAiAPLRINT
OrthoDBi349428at2759
PhylomeDBiQ9FNN2

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9FNN2

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR006595 CTLH_C
IPR020472 G-protein_beta_WD-40_rep
IPR006594 LisH
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00668 CTLH, 1 hit
SM00667 LisH, 1 hit
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50897 CTLH, 1 hit
PS50896 LISH, 1 hit
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWDR26_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FNN2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2017
Last sequence update: March 1, 2001
Last modified: February 13, 2019
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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