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UniProtKB - Q9FNB5 (AB6G_ARATH)

Entry version 137 (02 Dec 2020)
Sequence version 1 (01 Mar 2001)
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Protein

ABC transporter G family member 6

Gene

ABCG6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi126 – 133ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Protein family/group databases

Transport Classification Database

More...TCDBi		3.A.1.204.31, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ABC transporter G family member 6
Short name:
ABC transporter ABCG.6
Short name:
AtABCG6
Alternative name(s):
White-brown complex homolog protein 6
Short name:
AtWBC6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCG6
Synonyms:WBC6
Ordered Locus Names:At5g13580
ORF Names:MSH12.4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT5G13580

The Arabidopsis Information Resource

More...TAIRi		locus:2173184, AT5G13580

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei440 – 460HelicalSequence analysisAdd BLAST21
Transmembranei475 – 495HelicalSequence analysisAdd BLAST21
Transmembranei517 – 537HelicalSequence analysisAdd BLAST21
Transmembranei560 – 580HelicalSequence analysisAdd BLAST21
Transmembranei581 – 601HelicalSequence analysisAdd BLAST21
Transmembranei700 – 720HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002406781 – 727ABC transporter G family member 6Add BLAST727

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9FNB5

PRoteomics IDEntifications database

More...PRIDEi		Q9FNB5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		244614

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9FNB5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q9FNB5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9FNB5, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		16480, 14 interactors

Protein interaction database and analysis system

More...IntActi		Q9FNB5, 13 interactors

STRING: functional protein association networks

More...STRINGi		3702.AT5G13580.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini68 – 333ABC transporterPROSITE-ProRule annotationAdd BLAST266
Domaini421 – 631ABC transmembrane type-2Add BLAST211

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0061, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000604_57_8_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9FNB5

Identification of Orthologs from Complete Genome Data

More...OMAi		IHMAQSG

Database of Orthologous Groups

More...OrthoDBi		1022017at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9FNB5

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003593, AAA+_ATPase
IPR013525, ABC_2_trans
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR043926, ABCG_dom
IPR027417, P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01061, ABC2_membrane, 1 hit
PF19055, ABC2_membrane_7, 1 hit
PF00005, ABC_tran, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00382, AAA, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00211, ABC_TRANSPORTER_1, 1 hit
PS50893, ABC_TRANSPORTER_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9FNB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRVVAADDN MALPFFSPEF GNVSGASSSP TTFAQLLQNV DDSTRRSHHQ 
        60         70         80         90        100
HHVDVDLASP DQSVPFVLSF TDLTYSVKVR RKFTWRRSVS SDPGAPSEGI 
       110        120        130        140        150
FSSKTKTLLN GITGEARDGE ILAVLGASGS GKSTLIDALA NRIAKGSLKG 
       160        170        180        190        200
NVTLNGEVLN SKMQKAISAY VMQDDLLFPM LTVEETLMFA AEFRLPRSLS 
       210        220        230        240        250
KSKKSLRVQA LIDQLGLRNA ANTVIGDEGH RGISGGERRR VSIGIDIIHD 
       260        270        280        290        300
PILLFLDEPT SGLDSTSALS VIKVLKRIAQ SGSMVIMTLH QPSYRLLRLL 
       310        320        330        340        350
DRLLFLSRGQ TVFSGSPAML PRFFAEFGHP IPEHENRTEF ALDLIRELEG 
       360        370        380        390        400
SAGGTRSLVE FNKGFRQRKA EPRSQTGLSL KEAISASISK GKLVSGATTT 
       410        420        430        440        450
THSSGSSPVS TIPTFANPFW VELAVLAKRS MTNSRRQPEL FGIRLGAVLV 
       460        470        480        490        500
TGFILATMFW QLDNSPKGVQ ERLGCFAFAM STTFYTCADA LPVFLQERFI 
       510        520        530        540        550
FMRETAYNAY RRSSYVLSHS LVALPSLIIL SLAFAAITFW GVGLDGGLMG 
       560        570        580        590        600
FLFYFLVILA SFWAGSSFVT FLSGVVPHVM LGYTIVVAIL AYFLLFSGFF 
       610        620        630        640        650
INRDRIPGYW IWFHYISLVK YPYEAVLLNE FGDPTKCFVR GVQIFDNTPL 
       660        670        680        690        700
VAVPQGMKVR LLATMSKSLG MRITSSTCLT TGYDILQQQG VTDLTKWNCL 
       710        720 
WVTVAWGFFF RILFYFSLLL GSKNKRR
Length:727
Mass (Da):80,301
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6345CCF5877213A4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB006704 Genomic DNA Translation: BAB08684.1
CP002688 Genomic DNA Translation: AED91914.1
BT003884 mRNA Translation: AAO41933.1
BT004956 mRNA Translation: AAO50489.1

NCBI Reference Sequences

More...RefSeqi		NP_196862.1, NM_121361.3

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT5G13580.1; AT5G13580.1; AT5G13580

Database of genes from NCBI RefSeq genomes

More...GeneIDi		831202

Gramene; a comparative resource for plants

More...Gramenei		AT5G13580.1; AT5G13580.1; AT5G13580

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT5G13580

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006704 Genomic DNA Translation: BAB08684.1
CP002688 Genomic DNA Translation: AED91914.1
BT003884 mRNA Translation: AAO41933.1
BT004956 mRNA Translation: AAO50489.1
RefSeqiNP_196862.1, NM_121361.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi16480, 14 interactors
IntActiQ9FNB5, 13 interactors
STRINGi3702.AT5G13580.1

Protein family/group databases

TCDBi3.A.1.204.31, the atp-binding cassette (abc) superfamily

PTM databases

iPTMnetiQ9FNB5

Proteomic databases

PaxDbiQ9FNB5
PRIDEiQ9FNB5
ProteomicsDBi244614

Genome annotation databases

EnsemblPlantsiAT5G13580.1; AT5G13580.1; AT5G13580
GeneIDi831202
GrameneiAT5G13580.1; AT5G13580.1; AT5G13580
KEGGiath:AT5G13580

Organism-specific databases

AraportiAT5G13580
TAIRilocus:2173184, AT5G13580

Phylogenomic databases

eggNOGiKOG0061, Eukaryota
HOGENOMiCLU_000604_57_8_1
InParanoidiQ9FNB5
OMAiIHMAQSG
OrthoDBi1022017at2759
PhylomeDBiQ9FNB5

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q9FNB5

Gene expression databases

ExpressionAtlasiQ9FNB5, baseline and differential
GenevisibleiQ9FNB5, AT

Family and domain databases

InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR013525, ABC_2_trans
IPR003439, ABC_transporter-like
IPR017871, ABC_transporter_CS
IPR043926, ABCG_dom
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF01061, ABC2_membrane, 1 hit
PF19055, ABC2_membrane_7, 1 hit
PF00005, ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 1 hit
SUPFAMiSSF52540, SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211, ABC_TRANSPORTER_1, 1 hit
PS50893, ABC_TRANSPORTER_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAB6G_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FNB5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2001
Last modified: December 2, 2020
This is version 137 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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