Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 132 (11 Dec 2019)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1

Gene

At5g53850

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: L-methionine biosynthesis via salvage pathway

This protein is involved in step 2, 3 and 4 of the subpathway that synthesizes L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate.UniRule annotation
Proteins known to be involved in the 6 steps of the subpathway in this organism are:
  1. Methylthioribose-1-phosphate isomerase (At2g05830), Methylthioribose-1-phosphate isomerase (AXX17_At2g04890)
  2. Probable methylthioribulose-1-phosphate dehydratase (DEP1), Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 (At5g53850), Probable methylthioribulose-1-phosphate dehydratase (DEP1)
  3. Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 (At5g53850)
  4. Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 (At5g53850), Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 (DEP1)
  5. 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4 (ARD4), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (AXX17_At5g41930), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (AXX17_At4g16980), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ATARD2), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 (ARD2), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ATARD2), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1 (ARD1), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ARD3), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ARD3), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (AXX17_At2g22230), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (AXX17_At4g16990), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (At4g14716), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ARD1), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ATARD2), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 3 (ARD3), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ARD3), 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ATARD2)
  6. no protein annotated in this organism
This subpathway is part of the pathway L-methionine biosynthesis via salvage pathway, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate, the pathway L-methionine biosynthesis via salvage pathway and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei109Substrate; for methylthioribulose-1-phosphate dehydratase activityUniRule annotationBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi127Zinc; via tele nitrogenUniRule annotationBy similarity1
Metal bindingi129Zinc; via tele nitrogenUniRule annotationBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei152Proton donor/acceptorUniRule annotationBy similarity1
Metal bindingi202Zinc; via tele nitrogenUniRule annotationBy similarity1
Metal bindingi271MagnesiumUniRule annotation1
Metal bindingi273Magnesium; via carbonyl oxygenUniRule annotation1
Binding sitei440Substrate; for enolase-phosphatase activityUniRule annotation1
Metal bindingi466MagnesiumUniRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Lyase, Multifunctional enzyme
Biological processAmino-acid biosynthesis, Methionine biosynthesis
LigandMagnesium, Metal-binding, Zinc

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00904;UER00875
UPA00904;UER00876
UPA00904;UER00877

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1UniRule annotation
Including the following 2 domains:
Methylthioribulose-1-phosphate dehydrataseUniRule annotation (EC:4.2.1.109UniRule annotation)
Short name:
MTRu-1-P dehydrataseUniRule annotation
Enolase-phosphatase E1UniRule annotation (EC:3.1.3.77UniRule annotation)
Alternative name(s):
2,3-diketo-5-methylthio-1-phosphopentane phosphataseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At5g53850
ORF Names:K19P17.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G53850

The Arabidopsis Information Resource

More...
TAIRi
locus:2154664 AT5G53850

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003941552 – 507Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1Add BLAST506

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FN41

PRoteomics IDEntifications database

More...
PRIDEi
Q9FN41

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9FN41

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9FN41 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9FN41 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT5G53850.2

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9FN41

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2 – 237Methylthioribulose-1-phosphate dehydrataseUniRule annotationAdd BLAST236
Regioni268 – 507Enolase-phosphatase E1UniRule annotationAdd BLAST240
Regioni406 – 407Substrate binding; for enolase-phosphatase activityUniRule annotation2

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the aldolase class II family. MtnB subfamily.UniRule annotation
In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2630 Eukaryota
KOG2631 Eukaryota
COG0235 LUCA
COG4229 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000029320

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FN41

KEGG Orthology (KO)

More...
KOi
K16054

Database of Orthologous Groups

More...
OrthoDBi
436252at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FN41

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01629 HAD_EP, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.225.10, 1 hit
3.40.50.1000, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_03116 Salvage_MtnB_euk, 1 hit
MF_03118 Salvage_MtnBC, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001303 Aldolase_II/adducin_N
IPR036409 Aldolase_II/adducin_N_sf
IPR023943 Enolase-ppase_E1
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR017714 MethylthioRu-1-P_deHdtase_MtnB
IPR027505 MtnB_viridiplantae
IPR027514 Salvage_MtnB_euk

The PANTHER Classification System

More...
PANTHERi
PTHR10640 PTHR10640, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00596 Aldolase_II, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01007 Aldolase_II, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53639 SSF53639, 1 hit
SSF56784 SSF56784, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01691 enolase-ppase, 1 hit
TIGR01549 HAD-SF-IA-v1, 1 hit
TIGR03328 salvage_mtnB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9FN41-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAVAAAAMIG LPQAYLEGKE VKETSSLVTE LCRHFYTQGW VSGTGGSITM
60 70 80 90 100
KVHDASIPKP EQLIVMSPSG VQKERMQPED MYILSANGSI ISTPSPKPYP
110 120 130 140 150
NKPPKCTDCA PLFMKAYEMR NAGAVIHSHG MESCLVTMLN PQAKEFRITH
160 170 180 190 200
MEMIKGIQGH GYYDELVVPI IENTAYENEL TDSLTKAIEA YPKATAVLVR
210 220 230 240 250
NHGVYIWGDS WIHAKTQAEC YHYLFDAAIK LHQLGLDAAT PDHGPIRRTI
260 270 280 290 300
HSQIKDSQYE REWPRRWIVL DIEGTTTPIT FVTDVLFPYA RENVGKHLNL
310 320 330 340 350
TYHTAETQED IKLLRAQVEE DLREGVTGAV PIPHADEGKE KVIAAMVSNV
360 370 380 390 400
EAMIRADRKI TALKELQGHI WRTGFECDEL KAIVFEDVAD ALEKWHSSGI
410 420 430 440 450
KVYIYSSGSR LAQKLLFGNT DYGDLRKYIS GFFDTTIGNK KESRSYKEIK
460 470 480 490 500
ETLGVDDPAE IMFVTDVYQE AVAAKAAGLE AIISIRPGNA PLPENHGFKT

VTSFSQI
Length:507
Mass (Da):56,521
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2F99D9F52FA1D5DC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8BAY5A0A1P8BAY5_ARATH
Probable bifunctional methylthiorib...
DEP1 At5g53850, K19P17.1, K19P17_1
523Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F4JYQ5F4JYQ5_ARATH
Probable methylthioribulose-1-phosp...
DEP1 At5g53850, K19P17.1, K19P17_1
402Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F4JYQ6F4JYQ6_ARATH
Probable methylthioribulose-1-phosp...
DEP1 At5g53850, K19P17.1, K19P17_1
418Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A178UQC1A0A178UQC1_ARATH
Haloacid dehalogenase-like hydrolas...
DEP1 At5g53850, K19P17.1, K19P17_1
418Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BAY8A0A1P8BAY8_ARATH
Haloacid dehalogenase-like hydrolas...
DEP1 At5g53850, K19P17.1, K19P17_1
427Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti192P → S in BAF01056 (Ref. 4) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB007644 Genomic DNA Translation: BAB10715.1
CP002688 Genomic DNA Translation: AED96413.1
BT012606 mRNA Translation: AAT06425.1
BT015100 mRNA Translation: AAT71972.1
AK229186 mRNA Translation: BAF01056.1

NCBI Reference Sequences

More...
RefSeqi
NP_974931.1, NM_203202.3 [Q9FN41-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G53850.2; AT5G53850.2; AT5G53850 [Q9FN41-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
835466

Gramene; a comparative resource for plants

More...
Gramenei
AT5G53850.2; AT5G53850.2; AT5G53850 [Q9FN41-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G53850

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007644 Genomic DNA Translation: BAB10715.1
CP002688 Genomic DNA Translation: AED96413.1
BT012606 mRNA Translation: AAT06425.1
BT015100 mRNA Translation: AAT71972.1
AK229186 mRNA Translation: BAF01056.1
RefSeqiNP_974931.1, NM_203202.3 [Q9FN41-1]

3D structure databases

SMRiQ9FN41
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G53850.2

PTM databases

iPTMnetiQ9FN41

Proteomic databases

PaxDbiQ9FN41
PRIDEiQ9FN41

Genome annotation databases

EnsemblPlantsiAT5G53850.2; AT5G53850.2; AT5G53850 [Q9FN41-1]
GeneIDi835466
GrameneiAT5G53850.2; AT5G53850.2; AT5G53850 [Q9FN41-1]
KEGGiath:AT5G53850

Organism-specific databases

AraportiAT5G53850
TAIRilocus:2154664 AT5G53850

Phylogenomic databases

eggNOGiKOG2630 Eukaryota
KOG2631 Eukaryota
COG0235 LUCA
COG4229 LUCA
HOGENOMiHOG000029320
InParanoidiQ9FN41
KOiK16054
OrthoDBi436252at2759
PhylomeDBiQ9FN41

Enzyme and pathway databases

UniPathwayiUPA00904;UER00875
UPA00904;UER00876
UPA00904;UER00877

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9FN41

Gene expression databases

ExpressionAtlasiQ9FN41 baseline and differential
GenevisibleiQ9FN41 AT

Family and domain databases

CDDicd01629 HAD_EP, 1 hit
Gene3Di3.40.225.10, 1 hit
3.40.50.1000, 1 hit
HAMAPiMF_03116 Salvage_MtnB_euk, 1 hit
MF_03118 Salvage_MtnBC, 1 hit
InterProiView protein in InterPro
IPR001303 Aldolase_II/adducin_N
IPR036409 Aldolase_II/adducin_N_sf
IPR023943 Enolase-ppase_E1
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR023214 HAD_sf
IPR017714 MethylthioRu-1-P_deHdtase_MtnB
IPR027505 MtnB_viridiplantae
IPR027514 Salvage_MtnB_euk
PANTHERiPTHR10640 PTHR10640, 1 hit
PfamiView protein in Pfam
PF00596 Aldolase_II, 1 hit
SMARTiView protein in SMART
SM01007 Aldolase_II, 1 hit
SUPFAMiSSF53639 SSF53639, 1 hit
SSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01691 enolase-ppase, 1 hit
TIGR01549 HAD-SF-IA-v1, 1 hit
TIGR03328 salvage_mtnB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTBC_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FN41
Secondary accession number(s): Q0WP93
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: March 1, 2001
Last modified: December 11, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again