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UniProtKB - Q9FMU6 (MPCP3_ARATH)
Protein
Mitochondrial phosphate carrier protein 3, mitochondrial
Gene
MPT3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transport of phosphate groups from the cytosol to the mitochondrial matrix. Mediates salt stress tolerance through an ATP-dependent pathway and via modulation of the gibberellin metabolism.
2 PublicationsMiscellaneous
Plants overexpressing MPT3/PHT3;1 display increased sensitivity to salt stress.1 Publication
GO - Molecular functioni
- inorganic phosphate transmembrane transporter activity Source: GO_Central
- mRNA binding Source: TAIR
GO - Biological processi
- mitochondrial phosphate ion transmembrane transport Source: InterPro
- phosphate ion transmembrane transport Source: GO_Central
- response to salt stress Source: TAIR
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BRENDAi | 7.3.2.1, 399 |
Protein family/group databases
TCDBi | 2.A.29.4.6, the mitochondrial carrier (mc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Mitochondrial phosphate carrier protein 3, mitochondrialAlternative name(s): Mitochondrial phosphate transporter 3 Short name: MPT3 Phosphate transporter 3;1 |
Gene namesi | Name:MPT3 Synonyms:AT5, PHT3;1 Ordered Locus Names:At5g14040 ORF Names:MUA22_4 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G14040 |
TAIRi | locus:2174688, AT5G14040 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane 1 Publication; Multi-pass membrane protein 1 Publication
Cell Wall
- plant-type cell wall Source: TAIR
Mitochondrion
- integral component of mitochondrial inner membrane Source: GO_Central
- mitochondrion Source: TAIR
Vacuole
- plant-type vacuole Source: TAIR
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | ? – 75 | Mitochondrial intermembraneSequence analysis | ||
Transmembranei | 76 – 96 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 97 – 134 | Mitochondrial matrixSequence analysisAdd BLAST | 38 | |
Transmembranei | 135 – 154 | Helical; Name=2Sequence analysisAdd BLAST | 20 | |
Topological domaini | 155 – 175 | Mitochondrial intermembraneSequence analysisAdd BLAST | 21 | |
Transmembranei | 176 – 196 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 197 – 231 | Mitochondrial matrixSequence analysisAdd BLAST | 35 | |
Transmembranei | 232 – 251 | Helical; Name=4Sequence analysisAdd BLAST | 20 | |
Topological domaini | 252 – 272 | Mitochondrial intermembraneSequence analysisAdd BLAST | 21 | |
Transmembranei | 273 – 293 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 294 – 332 | Mitochondrial matrixSequence analysisAdd BLAST | 39 | |
Transmembranei | 333 – 353 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 354 – 375 | Mitochondrial intermembraneSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – ? | MitochondrionSequence analysis | ||
ChainiPRO_0000421697 | ? – 375 | Mitochondrial phosphate carrier protein 3, mitochondrial |
Proteomic databases
PaxDbi | Q9FMU6 |
PRIDEi | Q9FMU6 |
ProteomicsDBi | 239065 |
Expressioni
Tissue specificityi
Expressed in stems, leaves and flowers. Strong expression in vascular tissues.1 Publication
Inductioni
By salt stress.1 Publication
Gene expression databases
ExpressionAtlasi | Q9FMU6, baseline and differential |
Genevisiblei | Q9FMU6, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 16530, 24 interactors |
IntActi | Q9FMU6, 1 interactor |
MINTi | Q9FMU6 |
STRINGi | 3702.AT5G14040.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 76 – 160 | Solcar 1Add BLAST | 85 | |
Repeati | 173 – 257 | Solcar 2Add BLAST | 85 | |
Repeati | 274 – 353 | Solcar 3Add BLAST | 80 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transit peptide, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0767, Eukaryota |
HOGENOMi | CLU_039456_0_1_1 |
InParanoidi | Q9FMU6 |
OMAi | MISRKNF |
OrthoDBi | 963446at2759 |
PhylomeDBi | Q9FMU6 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf IPR044677, Pic2/Mir1-like |
PANTHERi | PTHR45671, PTHR45671, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 2 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q9FMU6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MESPKNSLIP SFLYSSSSSP RSFLLDQVLN SNSNAAFEKS PSPAPRSSPT
60 70 80 90 100
SMISRKNFLI ASPTEPGKGI EMYSPAFYAA CTFGGILSCG LTHMTVTPLD
110 120 130 140 150
LVKCNMQIDP AKYKSISSGF GILLKEQGVK GFFRGWVPTL LGYSAQGACK
160 170 180 190 200
FGFYEYFKKT YSDLAGPEYT AKYKTLIYLA GSASAEIIAD IALCPFEAVK
210 220 230 240 250
VRVQTQPGFA RGMSDGFPKF IKSEGYGGLY KGLAPLWGRQ IPYTMMKFAS
260 270 280 290 300
FETIVEMIYK YAIPNPKSEC SKGLQLGVSF AGGYVAGVFC AIVSHPADNL
310 320 330 340 350
VSFLNNAKGA TVGDAVKKIG MVGLFTRGLP LRIVMIGTLT GAQWGLYDAF
360 370
KVFVGLPTTG GVAPAPAIAA TEAKA
Sequence cautioni
The sequence BAD94852 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB007650 Genomic DNA Translation: BAB08283.1 CP002688 Genomic DNA Translation: AED91980.1 AY058848 mRNA Translation: AAL24236.1 AY143869 mRNA Translation: AAN28808.1 AB016066 mRNA Translation: BAA31585.1 AK222060 mRNA Translation: BAD94852.1 Different initiation. |
PIRi | T51595 |
RefSeqi | NP_196908.1, NM_121407.3 |
Genome annotation databases
EnsemblPlantsi | AT5G14040.1; AT5G14040.1; AT5G14040 |
GeneIDi | 831252 |
Gramenei | AT5G14040.1; AT5G14040.1; AT5G14040 |
KEGGi | ath:AT5G14040 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB007650 Genomic DNA Translation: BAB08283.1 CP002688 Genomic DNA Translation: AED91980.1 AY058848 mRNA Translation: AAL24236.1 AY143869 mRNA Translation: AAN28808.1 AB016066 mRNA Translation: BAA31585.1 AK222060 mRNA Translation: BAD94852.1 Different initiation. |
PIRi | T51595 |
RefSeqi | NP_196908.1, NM_121407.3 |
3D structure databases
AlphaFoldDBi | Q9FMU6 |
SMRi | Q9FMU6 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 16530, 24 interactors |
IntActi | Q9FMU6, 1 interactor |
MINTi | Q9FMU6 |
STRINGi | 3702.AT5G14040.1 |
Protein family/group databases
TCDBi | 2.A.29.4.6, the mitochondrial carrier (mc) family |
Proteomic databases
PaxDbi | Q9FMU6 |
PRIDEi | Q9FMU6 |
ProteomicsDBi | 239065 |
Genome annotation databases
EnsemblPlantsi | AT5G14040.1; AT5G14040.1; AT5G14040 |
GeneIDi | 831252 |
Gramenei | AT5G14040.1; AT5G14040.1; AT5G14040 |
KEGGi | ath:AT5G14040 |
Organism-specific databases
Araporti | AT5G14040 |
TAIRi | locus:2174688, AT5G14040 |
Phylogenomic databases
eggNOGi | KOG0767, Eukaryota |
HOGENOMi | CLU_039456_0_1_1 |
InParanoidi | Q9FMU6 |
OMAi | MISRKNF |
OrthoDBi | 963446at2759 |
PhylomeDBi | Q9FMU6 |
Enzyme and pathway databases
BRENDAi | 7.3.2.1, 399 |
Miscellaneous databases
PROi | PR:Q9FMU6 |
Gene expression databases
ExpressionAtlasi | Q9FMU6, baseline and differential |
Genevisiblei | Q9FMU6, AT |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf IPR044677, Pic2/Mir1-like |
PANTHERi | PTHR45671, PTHR45671, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 2 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | MPCP3_ARATH | |
Accessioni | Q9FMU6Primary (citable) accession number: Q9FMU6 Secondary accession number(s): O80415, Q56WI0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 6, 2013 |
Last sequence update: | March 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 132 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families