We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q9FKB6 (Y5880_ARATH)
Protein
BTB/POZ domain-containing protein At5g48800
Gene
At5g48800
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
By similarity: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
GO - Biological processi
- protein ubiquitination Source: UniProtKB-UniPathway
Keywordsi
Biological process | Ubl conjugation pathway |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
Names & Taxonomyi
Protein namesi | Recommended name: BTB/POZ domain-containing protein At5g48800 |
Gene namesi | Ordered Locus Names:At5g48800 ORF Names:K24G6.13 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G48800 |
TAIRi | locus:2156524, AT5G48800 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000315353 | 1 – 614 | BTB/POZ domain-containing protein At5g48800Add BLAST | 614 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 425 | PhosphotyrosineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | Q9FKB6 |
PRIDEi | Q9FKB6 |
ProteomicsDBi | 242881 [Q9FKB6-1] |
PTM databases
iPTMneti | Q9FKB6 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q9FKB6, baseline and differential |
Genevisiblei | Q9FKB6, AT |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 43 – 111 | BTBPROSITE-ProRule annotationAdd BLAST | 69 | |
Domaini | 219 – 484 | NPH3PROSITE-ProRule annotationAdd BLAST | 266 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 492 – 525 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 583 – 614 | DisorderedSequence analysisAdd BLAST | 32 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 522 – 562 | Sequence analysisAdd BLAST | 41 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 583 – 600 | Polar residuesSequence analysisAdd BLAST | 18 |
Domaini
The BTB/POZ domain mediates the interaction with some component of ubiquitin ligase complexes.1 Publication
Sequence similaritiesi
Belongs to the NPH3 family.PROSITE-ProRule annotation
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG502R4F9, Eukaryota |
HOGENOMi | CLU_005994_6_0_1 |
InParanoidi | Q9FKB6 |
OMAi | QQQSWRI |
PhylomeDBi | Q9FKB6 |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR043454, NPH3/RPT2-like IPR027356, NPH3_dom IPR011333, SKP1/BTB/POZ_sf |
PANTHERi | PTHR32370, PTHR32370, 1 hit |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF03000, NPH3, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS51649, NPH3, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q9FKB6-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDKHHHQHLL LQHHQHLHHH QKLSLAKSSR QSCSEWIFRD VPSDITIEVN
60 70 80 90 100
GGNFALHKFP LVSRSGRIRR IVAEHRDSDI SKVELLNLPG GAETFELAAK
110 120 130 140 150
FCYGINFEIT SSNVAQLFCV SDYLEMTEEY SKDNLASRTE EYLESIVCKN
160 170 180 190 200
LEMCVQVLKQ SEILLPLADE LNIIGRCIDA IASKACAEQI ASSFSRLEYS
210 220 230 240 250
SSGRLHMSRQ VKSSGDGGDW WIEDLSVLRI DLYQRVMNAM KCRGVRPESI
260 270 280 290 300
GASLVSYAER ELTKRSEHEQ TIVETIVTLL PVENLVVPIS FLFGLLRRAV
310 320 330 340 350
ILDTSVSCRL DLERRLGSQL DMATLDDLLI PSFRHAGDTL FDIDTVHRIL
360 370 380 390 400
VNFSQQGGDD SEDEESVFEC DSPHSPSQTA MFKVAKLVDS YLAEIAPDAN
410 420 430 440 450
LDLSKFLLIA EALPPHARTL HDGLYRAIDL YLKAHQGLSD SDKKKLSKLI
460 470 480 490 500
DFQKLSQEAG AHAAQNERLP LQSIVQVLYF EQLKLRSSLC SSYSDEEPKP
510 520 530 540 550
KQQQQQSWRI NSGALSATMS PKDNYASLRR ENRELKLELA RLRMRLNDLE
560 570 580 590 600
KEHICMKRDM QRSHSRKFMS SFSKKMGKLS FFGHSSSRGS SSPSKQSFRT
610
DSKVLMERTC ASTD
Sequence cautioni
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_030534 | 316 – 321 | LGSQLD → RHFVR in isoform 2. 1 Publication | 6 | |
Alternative sequenceiVSP_030535 | 322 – 614 | Missing in isoform 2. 1 PublicationAdd BLAST | 293 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012242 Genomic DNA Translation: BAB09433.1 CP002688 Genomic DNA Translation: AED95726.1 AK117251 mRNA Translation: BAC41926.1 BX830207 mRNA No translation available. |
RefSeqi | NP_199691.1, NM_124257.4 [Q9FKB6-1] |
Genome annotation databases
EnsemblPlantsi | AT5G48800.1; AT5G48800.1; AT5G48800 [Q9FKB6-1] |
GeneIDi | 834938 |
Gramenei | AT5G48800.1; AT5G48800.1; AT5G48800 [Q9FKB6-1] |
KEGGi | ath:AT5G48800 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB012242 Genomic DNA Translation: BAB09433.1 CP002688 Genomic DNA Translation: AED95726.1 AK117251 mRNA Translation: BAC41926.1 BX830207 mRNA No translation available. |
RefSeqi | NP_199691.1, NM_124257.4 [Q9FKB6-1] |
3D structure databases
SMRi | Q9FKB6 |
ModBasei | Search... |
PTM databases
iPTMneti | Q9FKB6 |
Proteomic databases
PaxDbi | Q9FKB6 |
PRIDEi | Q9FKB6 |
ProteomicsDBi | 242881 [Q9FKB6-1] |
Genome annotation databases
EnsemblPlantsi | AT5G48800.1; AT5G48800.1; AT5G48800 [Q9FKB6-1] |
GeneIDi | 834938 |
Gramenei | AT5G48800.1; AT5G48800.1; AT5G48800 [Q9FKB6-1] |
KEGGi | ath:AT5G48800 |
Organism-specific databases
Araporti | AT5G48800 |
TAIRi | locus:2156524, AT5G48800 |
Phylogenomic databases
eggNOGi | ENOG502R4F9, Eukaryota |
HOGENOMi | CLU_005994_6_0_1 |
InParanoidi | Q9FKB6 |
OMAi | QQQSWRI |
PhylomeDBi | Q9FKB6 |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
Miscellaneous databases
PROi | PR:Q9FKB6 |
Gene expression databases
ExpressionAtlasi | Q9FKB6, baseline and differential |
Genevisiblei | Q9FKB6, AT |
Family and domain databases
Gene3Di | 3.30.710.10, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR043454, NPH3/RPT2-like IPR027356, NPH3_dom IPR011333, SKP1/BTB/POZ_sf |
PANTHERi | PTHR32370, PTHR32370, 1 hit |
Pfami | View protein in Pfam PF00651, BTB, 1 hit PF03000, NPH3, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit PS51649, NPH3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Y5880_ARATH | |
Accessioni | Q9FKB6Primary (citable) accession number: Q9FKB6 Secondary accession number(s): Q8GZ23 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 23, 2022 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families