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Entry version 132 (11 Dec 2019)
Sequence version 3 (08 Feb 2011)
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Protein

Homeobox-leucine zipper protein HDG5

Gene

HDG5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcription factor.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi111 – 170HomeoboxPROSITE-ProRule annotationAdd BLAST60

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • maintenance of floral organ identity Source: TAIR

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Homeobox-leucine zipper protein HDG5
Alternative name(s):
HD-ZIP protein HDG5
Homeodomain GLABRA 2-like protein 5
Homeodomain transcription factor HDG5
Protein HOMEODOMAIN GLABROUS 5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HDG5
Synonyms:HDGL2-5
Ordered Locus Names:At5g46880
ORF Names:MQD22.1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G46880

The Arabidopsis Information Resource

More...
TAIRi
locus:2170957 AT5G46880

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003316671 – 826Homeobox-leucine zipper protein HDG5Add BLAST826

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FJS2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in shoot apical meristem (SAM) with higher levels in L1 cells and the epidermal layer of young leaves. Expressed in the L1 of apical inflorescence meristems, early flower primordia, carpel and stamen filament epidermis, ovule primordia, nucellus and chalaze.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9FJS2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9FJS2 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT5G46880.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9FJS2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini314 – 558STARTPROSITE-ProRule annotationAdd BLAST245

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili165 – 189Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi24 – 27Poly-Ser4
Compositional biasi304 – 310Poly-Asn7

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Coiled coil, Homeobox

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IH8K Eukaryota
ENOG410YCQU LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000243256

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FJS2

Identification of Orthologs from Complete Genome Data

More...
OMAi
VEHMEMV

Database of Orthologous Groups

More...
OrthoDBi
223056at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FJS2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00086 homeodomain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR042160 GLABRA2/ANL2/PDF2/ATML1-like
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR002913 START_lipid-bd_dom

The PANTHER Classification System

More...
PANTHERi
PTHR45654 PTHR45654, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00046 Homeodomain, 1 hit
PF01852 START, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00389 HOX, 1 hit
SM00234 START, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689 SSF46689, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS50848 START, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9FJS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLTMGEGNVM TSNNRFASPP QQPSSSSPGT IQNPNFNFIP FNSYSSIIPK
60 70 80 90 100
EEHGMMSMMM MMGDGTVEEM MENGSAGGSF GSGSEQAEDP KFGNESDVNE
110 120 130 140 150
LHDDEQPPPA KKKRYHRHTN RQIQEMEALF KENPHPDDKQ RKRLSAELGL
160 170 180 190 200
KPRQVKFWFQ NRRTQMKAQQ DRNENVMLRA ENDNLKSENC HLQAELRCLS
210 220 230 240 250
CPSCGGPTVL GDIPFNEIHI ENCRLREELD RLCCIASRYT GRPMQSMPPS
260 270 280 290 300
QPLINPSPML PHHQPSLELD MSVYAGNFPE QSCTDMMMLP PQDTACFFPD
310 320 330 340 350
QTANNNNNNN MLLADEEKVI AMEFAVSCVQ ELTKMCDTEE PLWIKKKSDK
360 370 380 390 400
IGGEILCLNE EEYMRLFPWP MENQNNKGDF LREASKANAV VIMNSITLVD
410 420 430 440 450
AFLNADKWSE MFCSIVARAK TVQIISSGVS GASGSLLLMF AELQVLSPLV
460 470 480 490 500
PTREAYFLRY VEQNAETGNW AIVDFPIDSF HDQMQPMNTI THEYKRKPSG
510 520 530 540 550
CIIQDMPNGY SQVKWVEHVE VDEKHVHETF AEYVKSGMAF GANRWLDVLQ
560 570 580 590 600
RQCERIASLM ARNITDLGVI SSAEARRNIM RLSQRLVKTF CVNISTAYGQ
610 620 630 640 650
SWTALSETTK DTVRITTRKM CEPGQPTGVV LCAVSTTWLP FSHHQVFDLI
660 670 680 690 700
RDQHHQSLLE VLFNGNSPHE VAHIANGSHP GNCISLLRIN VASNSWHNVE
710 720 730 740 750
LMLQESCIDN SGSLIVYSTV DVDSIQQAMN GEDSSNIPIL PLGFSIVPVN
760 770 780 790 800
PPEGISVNSH SPPSCLLTVG IQVLASNVPT AKPNLSTVTT INNHLCATVN
810 820
QITSALSNTI TPVIASSADV SNQEVS
Length:826
Mass (Da):92,120
Last modified:February 8, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF890788BB91735A2
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB10227 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BX841652 differs from that shown. Sequencing errors.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB013394 Genomic DNA Translation: BAB10227.1 Sequence problems.
CP002688 Genomic DNA Translation: AED95443.1
CP002688 Genomic DNA Translation: ANM68239.1
CP002688 Genomic DNA Translation: ANM68240.1
BX841652 mRNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001318750.1, NM_001344703.1
NP_001330010.1, NM_001344704.1
NP_199499.3, NM_124059.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G46880.1; AT5G46880.1; AT5G46880
AT5G46880.2; AT5G46880.2; AT5G46880
AT5G46880.3; AT5G46880.3; AT5G46880

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
834733

Gramene; a comparative resource for plants

More...
Gramenei
AT5G46880.1; AT5G46880.1; AT5G46880
AT5G46880.2; AT5G46880.2; AT5G46880
AT5G46880.3; AT5G46880.3; AT5G46880

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G46880

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013394 Genomic DNA Translation: BAB10227.1 Sequence problems.
CP002688 Genomic DNA Translation: AED95443.1
CP002688 Genomic DNA Translation: ANM68239.1
CP002688 Genomic DNA Translation: ANM68240.1
BX841652 mRNA No translation available.
RefSeqiNP_001318750.1, NM_001344703.1
NP_001330010.1, NM_001344704.1
NP_199499.3, NM_124059.4

3D structure databases

SMRiQ9FJS2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G46880.1

Proteomic databases

PaxDbiQ9FJS2

Genome annotation databases

EnsemblPlantsiAT5G46880.1; AT5G46880.1; AT5G46880
AT5G46880.2; AT5G46880.2; AT5G46880
AT5G46880.3; AT5G46880.3; AT5G46880
GeneIDi834733
GrameneiAT5G46880.1; AT5G46880.1; AT5G46880
AT5G46880.2; AT5G46880.2; AT5G46880
AT5G46880.3; AT5G46880.3; AT5G46880
KEGGiath:AT5G46880

Organism-specific databases

AraportiAT5G46880
TAIRilocus:2170957 AT5G46880

Phylogenomic databases

eggNOGiENOG410IH8K Eukaryota
ENOG410YCQU LUCA
HOGENOMiHOG000243256
InParanoidiQ9FJS2
OMAiVEHMEMV
OrthoDBi223056at2759
PhylomeDBiQ9FJS2

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9FJS2

Gene expression databases

ExpressionAtlasiQ9FJS2 baseline and differential
GenevisibleiQ9FJS2 AT

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR042160 GLABRA2/ANL2/PDF2/ATML1-like
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR002913 START_lipid-bd_dom
PANTHERiPTHR45654 PTHR45654, 2 hits
PfamiView protein in Pfam
PF00046 Homeodomain, 1 hit
PF01852 START, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00234 START, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS50848 START, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHDG5_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FJS2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: February 8, 2011
Last modified: December 11, 2019
This is version 132 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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