UniProtKB - Q9FJL4 (BH078_ARATH)
Protein
Transcription factor bHLH78
Gene
BHLH78
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Transcription factor that binds DNA to G box 5'-CACGTG-3' and to E-box 5'-CANNTG-3' (By similarity). Binds to chromatin DNA of the FT gene and promotes its expression, and thus triggers flowering in response to blue light (PubMed:24130508).By similarity1 Publication
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription factor activity Source: TAIR
- protein dimerization activity Source: InterPro
GO - Biological processi
- regulation of transcription, DNA-templated Source: TAIR
- response to blue light Source: UniProtKB
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription factor bHLH78Alternative name(s): Basic helix-loop-helix protein 78 Short name: AtbHLH78 Short name: bHLH 78 Transcription factor EN 86 bHLH transcription factor bHLH078 |
Gene namesi | Name:BHLH78 Synonyms:CIB2, EN86 Ordered Locus Names:At5g48560 ORF Names:K15N18.2 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G48560 |
TAIRi | locus:2152551, AT5G48560 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000358770 | 1 – 498 | Transcription factor bHLH78Add BLAST | 498 |
Proteomic databases
PaxDbi | Q9FJL4 |
ProteomicsDBi | 240863 |
Expressioni
Tissue specificityi
Expressed constitutively in roots, leaves, stems, and flowers.1 Publication
Gene expression databases
ExpressionAtlasi | Q9FJL4, baseline and differential |
Genevisiblei | Q9FJL4, AT |
Interactioni
Subunit structurei
Homodimer (Probable). Binds reversibly to CRY2 after blue light illumination (PubMed:24130508).
Curated1 PublicationGO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
BioGRIDi | 20158, 3 interactors |
IntActi | Q9FJL4, 1 interactor |
STRINGi | 3702.AT5G48560.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 307 – 357 | bHLHPROSITE-ProRule annotationAdd BLAST | 51 |
Phylogenomic databases
eggNOGi | ENOG502QRSF, Eukaryota |
HOGENOMi | CLU_025018_6_1_1 |
InParanoidi | Q9FJL4 |
OMAi | SLMPKEM |
OrthoDBi | 616690at2759 |
PhylomeDBi | Q9FJL4 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR024097, bHLH_ZIP_TF IPR036638, HLH_DNA-bd_sf |
PANTHERi | PTHR12565, PTHR12565, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9FJL4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDNELFMNTE FPPPPEMATH FEHQQSSSSA MMLNWALMDP NPHQDSSFLW
60 70 80 90 100
EKSTEQQQQQ SIFDSALSSL VSSPTPSNSN FSGGGGDGFL IRELIGKLGN
110 120 130 140 150
IGNNNNNSGE IYGTPMSRSA SCYATPMSSP PPPTNSNSQM MMNRTTPLTE
160 170 180 190 200
FSADPGFAER AARFSCFGSR SFNGRTNTNL PINNGNNMVN NSGKLTRVSS
210 220 230 240 250
TPALKALVSP EVTPGGEFSR KRKSVPKGKS KENPISTASP SPSFSKTAEK
260 270 280 290 300
NGGKGGSKSS EEKGGKRRRE EEDDEEEEGE GEGNKSNNTK PPEPPKDYIH
310 320 330 340 350
VRARRGQATD SHSLAERVRR EKIGERMKLL QDLVPGCNKV TGKALMLDEI
360 370 380 390 400
INYVQSLQRQ VEFLSMKLSS VNDTRLDFNV DALVSKDVMI PSSNNRLHEE
410 420 430 440 450
GLQSKSSSHH HQQQLNIYNN NSQLLPNISS NNMMLQSPMN SLETSTLARS
460 470 480 490
FTHLPTLTQF TDSISQYQMF SEEDLQSIVG MGVAENPNNE SQHMKIEL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8B9W1 | A0A1P8B9W1_ARATH | Basic helix-loop-helix (BHLH) DNA-b... | CIB2 CRY2-interacting bHLH 2, At5g48560, K15N18.2, K15N18_2 | 467 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 280 | E → G in AAM10957 (PubMed:12679534).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF488610 mRNA Translation: AAM10957.1 AB015468 Genomic DNA Translation: BAB10689.1 CP002688 Genomic DNA Translation: AED95688.1 BT002945 mRNA Translation: AAO22758.1 BT005637 mRNA Translation: AAO64057.1 |
RefSeqi | NP_199667.1, NM_124232.4 |
Genome annotation databases
EnsemblPlantsi | AT5G48560.1; AT5G48560.1; AT5G48560 |
GeneIDi | 834912 |
Gramenei | AT5G48560.1; AT5G48560.1; AT5G48560 |
KEGGi | ath:AT5G48560 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF488610 mRNA Translation: AAM10957.1 AB015468 Genomic DNA Translation: BAB10689.1 CP002688 Genomic DNA Translation: AED95688.1 BT002945 mRNA Translation: AAO22758.1 BT005637 mRNA Translation: AAO64057.1 |
RefSeqi | NP_199667.1, NM_124232.4 |
3D structure databases
SMRi | Q9FJL4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 20158, 3 interactors |
IntActi | Q9FJL4, 1 interactor |
STRINGi | 3702.AT5G48560.1 |
Proteomic databases
PaxDbi | Q9FJL4 |
ProteomicsDBi | 240863 |
Genome annotation databases
EnsemblPlantsi | AT5G48560.1; AT5G48560.1; AT5G48560 |
GeneIDi | 834912 |
Gramenei | AT5G48560.1; AT5G48560.1; AT5G48560 |
KEGGi | ath:AT5G48560 |
Organism-specific databases
Araporti | AT5G48560 |
TAIRi | locus:2152551, AT5G48560 |
Phylogenomic databases
eggNOGi | ENOG502QRSF, Eukaryota |
HOGENOMi | CLU_025018_6_1_1 |
InParanoidi | Q9FJL4 |
OMAi | SLMPKEM |
OrthoDBi | 616690at2759 |
PhylomeDBi | Q9FJL4 |
Miscellaneous databases
PROi | PR:Q9FJL4 |
Gene expression databases
ExpressionAtlasi | Q9FJL4, baseline and differential |
Genevisiblei | Q9FJL4, AT |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR024097, bHLH_ZIP_TF IPR036638, HLH_DNA-bd_sf |
PANTHERi | PTHR12565, PTHR12565, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BH078_ARATH | |
Accessioni | Q9FJL4Primary (citable) accession number: Q9FJL4 Secondary accession number(s): Q8S3D4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 16, 2008 |
Last sequence update: | March 1, 2001 | |
Last modified: | October 7, 2020 | |
This is version 119 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names