Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 126 (11 Dec 2019)
Sequence version 1 (01 Mar 2001)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Geranylgeranyl transferase type-2 subunit alpha 2

Gene

RGTA2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -CCXX, CXXX, -XCCX and -XCXC, such as RABA1A, RABA2A, RABF2A and RABG2 (By similarity). Does not seem to be a functional Rab-GGT alpha subunit in vitro (PubMed:26589801).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

The enzymatic reaction requires the aid of the Rab escort protein REP.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionPrenyltransferase, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Geranylgeranyl transferase type-2 subunit alpha 2Curated (EC:2.5.1.60Curated)
Alternative name(s):
Geranylgeranyl transferase type II subunit alpha 2Curated
Rab geranylgeranyl transferase alpha subunit 21 Publication
Short name:
AtRGTA21 Publication
Short name:
Rab-GGT alpha 2Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RGTA21 Publication
Ordered Locus Names:At5g41820Imported
ORF Names:K16L22.10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G41820

The Arabidopsis Information Resource

More...
TAIRi
locus:2153015 AT5G41820

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004366101 – 687Geranylgeranyl transferase type-2 subunit alpha 2Add BLAST687

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FJ32

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9FJ32

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9FJ32 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterotrimer composed of the alpha subunit RGTA, the beta subunit RGTB and REP; within this trimer, RGTA and RGTB form the catalytic component, while REP mediates peptide substrate binding.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT5G41820.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati38 – 72PFTA 1PROSITE-ProRule annotationAdd BLAST35
Repeati83 – 117PFTA 2PROSITE-ProRule annotationAdd BLAST35
Repeati132 – 167PFTA 3PROSITE-ProRule annotationAdd BLAST36
Repeati168 – 203PFTA 4PROSITE-ProRule annotationAdd BLAST36
Repeati214 – 248PFTA 5PROSITE-ProRule annotationAdd BLAST35
Repeati523 – 545LRR 1Sequence analysisAdd BLAST23
Repeati546 – 567LRR 2Sequence analysisAdd BLAST22
Repeati568 – 591LRR 3Sequence analysisAdd BLAST24
Repeati592 – 616LRR 4Sequence analysisAdd BLAST25
Repeati646 – 668LRR 5Sequence analysisAdd BLAST23

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Leucine-rich repeat, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0529 Eukaryota
COG5536 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000030513

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FJ32

KEGG Orthology (KO)

More...
KOi
K14050

Identification of Orthologs from Complete Genome Data

More...
OMAi
AWHYRSV

Database of Orthologous Groups

More...
OrthoDBi
1527547at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FJ32

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR002088 Prenyl_trans_a
IPR032955 RabGGTase_alpha

The PANTHER Classification System

More...
PANTHERi
PTHR11129:SF2 PTHR11129:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01239 PPTA, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450 LRR, 3 hits
PS51147 PFTA, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9FJ32-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHGRKREEDP NPEETAAKAL ELRSLQSQFM SNHHQKIYTK EAIQLSAKLL
60 70 80 90 100
ITNPEFYTAW NYPKLAFESR LDEDSDPSLV NSIIDEELGV VQNALERNVK
110 120 130 140 150
SYGAWYHRKW VLSKKGHYYP SLENELQLLN DYQKQAHQKQ DDEKQDDPSR
160 170 180 190 200
NFHAWNYRRF VVELTKTSEE DELQYTTDMI SDISFTIYSA WHYRSVLVSS
210 220 230 240 250
LVAKKADGFM PKETIRRELD YVHSAIFTLE EKQSGWFYYL WLLDQTVKME
260 270 280 290 300
IPLRFSSWPS DGSIIILSGP DCFNASSSTT KLTTFCSESG SFPLILYFDQ
310 320 330 340 350
AVSGVSSSTV TIGSELKDLV WEPVSDKKNS QVDSCVWVAR LKFDCREPCF
360 370 380 390 400
SRKETKVKVS LGGIVSSMGC NLTAPYEFVF TLRIHDTVEV ELSQQESIVS
410 420 430 440 450
WTDGFDNWDD NALSNDLNSL TALNADTGFE WRKKAIKIEI ELFRTLPDSK
460 470 480 490 500
IGKLILARLL MAEETMISNG VHYKEILQLY NDLMALDSWH NQYYKDEHSV
510 520 530 540 550
ALIHKVTSRT ESMSRHLFRY RNMNNIICLR LNNLTLSRIA AVEKLLFVQM
560 570 580 590 600
LDLSHNELHS AEGLEAMQLL CCLNLSHNRI RSFSALDSLR HLKQLRVLDV
610 620 630 640 650
SHNHICGELP VDTTRYLCSS PLSNSGETGR EVPNKYQDAY LVLRDLMKLK
660 670 680
QLDIRGNDLI FAGEEFSSFV RQVVPKLVWL DGHKLTS
Length:687
Mass (Da):79,141
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i89A26D1D4CF5F9F9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB016871 Genomic DNA Translation: BAB10657.1
CP002688 Genomic DNA Translation: AED94733.1
CP002688 Genomic DNA Translation: ANM70211.1

NCBI Reference Sequences

More...
RefSeqi
NP_001331841.1, NM_001344422.1
NP_198997.1, NM_123547.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G41820.1; AT5G41820.1; AT5G41820
AT5G41820.2; AT5G41820.2; AT5G41820

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
834187

Gramene; a comparative resource for plants

More...
Gramenei
AT5G41820.1; AT5G41820.1; AT5G41820
AT5G41820.2; AT5G41820.2; AT5G41820

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G41820

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB016871 Genomic DNA Translation: BAB10657.1
CP002688 Genomic DNA Translation: AED94733.1
CP002688 Genomic DNA Translation: ANM70211.1
RefSeqiNP_001331841.1, NM_001344422.1
NP_198997.1, NM_123547.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi3702.AT5G41820.1

PTM databases

iPTMnetiQ9FJ32

Proteomic databases

PaxDbiQ9FJ32

Genome annotation databases

EnsemblPlantsiAT5G41820.1; AT5G41820.1; AT5G41820
AT5G41820.2; AT5G41820.2; AT5G41820
GeneIDi834187
GrameneiAT5G41820.1; AT5G41820.1; AT5G41820
AT5G41820.2; AT5G41820.2; AT5G41820
KEGGiath:AT5G41820

Organism-specific databases

AraportiAT5G41820
TAIRilocus:2153015 AT5G41820

Phylogenomic databases

eggNOGiKOG0529 Eukaryota
COG5536 LUCA
HOGENOMiHOG000030513
InParanoidiQ9FJ32
KOiK14050
OMAiAWHYRSV
OrthoDBi1527547at2759
PhylomeDBiQ9FJ32

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q9FJ32

Gene expression databases

ExpressionAtlasiQ9FJ32 baseline and differential

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR002088 Prenyl_trans_a
IPR032955 RabGGTase_alpha
PANTHERiPTHR11129:SF2 PTHR11129:SF2, 1 hit
PfamiView protein in Pfam
PF01239 PPTA, 3 hits
PROSITEiView protein in PROSITE
PS51450 LRR, 3 hits
PS51147 PFTA, 5 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPGTA2_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FJ32
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 6, 2016
Last sequence update: March 1, 2001
Last modified: December 11, 2019
This is version 126 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again