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UniProtKB - Q9FIZ9 (NIP41_ARATH)
Protein
Putative aquaporin NIP4-1
Gene
NIP4-1
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Potential aquaporin, which may facilitate the transport of water and small neutral solutes across cell membranes.
By similarityGO - Molecular functioni
- channel activity Source: InterPro
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Putative aquaporin NIP4-1Alternative name(s): NOD26-like intrinsic protein 4-1 Short name: AtNIP4;1 |
Gene namesi | Name:NIP4-1 Ordered Locus Names:At5g37810 ORF Names:K22F20.50 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G37810 |
TAIRi | locus:2156020, AT5G37810 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 45 – 65 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 70 – 90 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 122 – 142 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 161 – 181 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 189 – 209 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 231 – 251 | Helical; Name=6Sequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000064066 | 1 – 283 | Putative aquaporin NIP4-1Add BLAST | 283 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineBy similarity | 1 | |
Modified residuei | 267 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
PaxDbi | Q9FIZ9 |
PRIDEi | Q9FIZ9 |
ProteomicsDBi | 251153 |
PTM databases
iPTMneti | Q9FIZ9 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 19010, 17 interactors |
IntActi | Q9FIZ9, 17 interactors |
STRINGi | 3702.AT5G37810.1 |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 102 – 104 | NPA 1 | 3 | |
Motifi | 214 – 216 | NPA 2 | 3 |
Domaini
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence similaritiesi
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0223, Eukaryota |
HOGENOMi | CLU_020019_3_1_1 |
InParanoidi | Q9FIZ9 |
OMAi | RADNICA |
OrthoDBi | 1152704at2759 |
PhylomeDBi | Q9FIZ9 |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45724, PTHR45724, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9FIZ9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSHSDEIEE EQISRIEKGK GKDCQGGIET VICTSPSIVC LTQKLIAEMI
60 70 80 90 100
GTYFIVFSGC GVVVVNVLYG GTITFPGICV TWGLIVMVMI YSTGHISGAH
110 120 130 140 150
FNPAVTVTFA IFRRFPWHQV PLYIGAQFAG SLLASLTLRL MFKVTPEAFF
160 170 180 190 200
GTTPADSPAR ALVAEIIISF LLMFVISGVA TDNRAVGELA GIAVGMTIMV
210 220 230 240 250
NVFVAGPISG ASMNPARSLG PALVMGVYKH IWVYIVGPVL GVISGGFVYN
260 270 280
LIRFTDKPLR ELTKSASFLR AVSPSHKGSS SKT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB016873 Genomic DNA Translation: BAB10360.1 CP002688 Genomic DNA Translation: AED94235.1 |
RefSeqi | NP_198597.1, NM_123140.2 |
Genome annotation databases
EnsemblPlantsi | AT5G37810.1; AT5G37810.1; AT5G37810 |
GeneIDi | 833759 |
Gramenei | AT5G37810.1; AT5G37810.1; AT5G37810 |
KEGGi | ath:AT5G37810 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB016873 Genomic DNA Translation: BAB10360.1 CP002688 Genomic DNA Translation: AED94235.1 |
RefSeqi | NP_198597.1, NM_123140.2 |
3D structure databases
AlphaFoldDBi | Q9FIZ9 |
SMRi | Q9FIZ9 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 19010, 17 interactors |
IntActi | Q9FIZ9, 17 interactors |
STRINGi | 3702.AT5G37810.1 |
PTM databases
iPTMneti | Q9FIZ9 |
Proteomic databases
PaxDbi | Q9FIZ9 |
PRIDEi | Q9FIZ9 |
ProteomicsDBi | 251153 |
Genome annotation databases
EnsemblPlantsi | AT5G37810.1; AT5G37810.1; AT5G37810 |
GeneIDi | 833759 |
Gramenei | AT5G37810.1; AT5G37810.1; AT5G37810 |
KEGGi | ath:AT5G37810 |
Organism-specific databases
Araporti | AT5G37810 |
TAIRi | locus:2156020, AT5G37810 |
Phylogenomic databases
eggNOGi | KOG0223, Eukaryota |
HOGENOMi | CLU_020019_3_1_1 |
InParanoidi | Q9FIZ9 |
OMAi | RADNICA |
OrthoDBi | 1152704at2759 |
PhylomeDBi | Q9FIZ9 |
Miscellaneous databases
PROi | PR:Q9FIZ9 |
Gene expression databases
ExpressionAtlasi | Q9FIZ9, baseline |
Genevisiblei | Q9FIZ9, AT |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45724, PTHR45724, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NIP41_ARATH | |
Accessioni | Q9FIZ9Primary (citable) accession number: Q9FIZ9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2003 |
Last sequence update: | March 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 136 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families