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Entry version 134 (18 Sep 2019)
Sequence version 1 (01 Mar 2001)
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Protein

Kinesin-like protein KIN-14E

Gene

KIN14E

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Minus-end microtubule-dependent motor protein involved in the regulation of cell division and trichome morphogenesis through microtubules bundling. Possesses basal and microtubule-stimulated ATPase activities. Acts as a hub that brings together microtubules and actin filaments to modulate the cytoskeleton during trichome formation and morphogenesis (PubMed:26287478). Could be involved in the negative regulation of root growth (PubMed:25262228).11 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi972 – 977ATPCombined sources6

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCalmodulin-binding, Motor protein
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kinesin-like protein KIN-14ECurated
Alternative name(s):
Kinesin-like calmodulin-binding protein2 Publications
Protein ZWICHEL1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KIN14ECurated
Synonyms:KCBPImported, ZWIImported
Ordered Locus Names:At5g65930Imported
ORF Names:K14B20.10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G65930

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Trichomes with reduced branch number (PubMed:9177205, PubMed:25262228, PubMed:26287478). Impairment of trichomes branch tip sharpening due to disrupted transverse cortical F-actin cap (PubMed:26287478).3 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi976T → N: Defective in ATP hydrolysis. Severe trichome phenotypes. 1 Publication1
Mutagenesisi1130C → N: No effect on binding to microtubule or regulation by KIC. 2 Publications1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004032731 – 1260Kinesin-like protein KIN-14EAdd BLAST1260

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9FHN8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9FHN8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with the highest levels in flowers (PubMed:8636137). Strongly expressed in the root tip (PubMed:25908862). Highly detected in the branch apex of the trichome (PubMed:26287478).3 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9FHN8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9FHN8 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (via C-terminus) (PubMed:23805258). Binds microtubules via its N-terminus containing the MyTH4 domain and binds F-actin via its FERM domain (PubMed:26287478).

Interacts with KIPK1 (PubMed:10788494, PubMed:25262228).

Interacts with KIPK2 (PubMed:25262228).

Interacts with AN (PubMed:11889034).

Interacts with AIR9 (PubMed:25908862).

Interacts (via C-terminus) with KIC, CAM2, CAM4 and CAM6. KIC and calmodulin show competitive binding to KCBP. Binding to calmodulin inhibits microtubule binding activity. Binding to KIC inhibits microtubule binding activity and microtubule-stimulated ATPase activity.

15 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
21965, 3 interactors

Database of interacting proteins

More...
DIPi
DIP-54846N

Protein interaction database and analysis system

More...
IntActi
Q9FHN8, 8 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G65930.3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11260
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9FHN8

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9FHN8

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini115 – 274MyTH4PROSITE-ProRule annotationAdd BLAST160
Domaini279 – 593FERMPROSITE-ProRule annotationAdd BLAST315
Domaini888 – 1209Kinesin motorPROSITE-ProRule annotationAdd BLAST322

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1217 – 1239Calmodulin-binding1 PublicationAdd BLAST23
Regioni1221 – 1260Homodimerization domain1 PublicationAdd BLAST40

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili615 – 676Sequence analysisAdd BLAST62
Coiled coili753 – 853Sequence analysisAdd BLAST101

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-14 subfamily.1 Publication

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG0239 Eukaryota
KOG4229 Eukaryota
COG5059 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000241108

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9FHN8

Database of Orthologous Groups

More...
OrthoDBi
364605at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9FHN8

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14473 FERM_B-lobe, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.80.10, 1 hit
1.25.40.530, 1 hit
2.30.29.30, 1 hit
3.40.850.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019749 Band_41_domain
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR018979 FERM_N
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
IPR011254 Prismane-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24115 PTHR24115, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF00225 Kinesin, 1 hit
PF00784 MyTH4, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00380 KINESINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00295 B41, 1 hit
SM00129 KISc, 1 hit
SM00139 MyTH4, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47031 SSF47031, 1 hit
SSF52540 SSF52540, 1 hit
SSF56821 SSF56821, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50057 FERM_3, 1 hit
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
PS51016 MYTH4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9FHN8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEGQRGSNSS LSSGNGTEVA TDVSSCFYVP NPSGTDFDAE SSSLPPLSPA
60 70 80 90 100
PQVALSIPAE LAAAIPLIDR FQVEAFLRLM QKQIQSAGKR GFFYSKKSSG
110 120 130 140 150
SNVRERFTFE DMLCFQKDPI PTSLLKINSD LVSRATKLFH LILKYMGVDS
160 170 180 190 200
SDRSTPPSLD ERIDLVGKLF KKTLKRVELR DELFAQISKQ TRHNPDRQYL
210 220 230 240 250
IKAWELMYLC ASSMPPSKDI GGYLSEYIHN VAHDATIEPD AQVLAVNTLK
260 270 280 290 300
ALKRSIKAGP RHTTPGREEI EALLTGRKLT TIVFFLDETF EEISYDMATT
310 320 330 340 350
VSDAVEELAG TIKLSAFSSF SLFECRKVVS SSKSSDPGNE EYIGLDDNKY
360 370 380 390 400
IGDLLAEFKA IKDRNKGEIL HCKLVFKKKL FRESDEAVTD LMFVQLSYVQ
410 420 430 440 450
LQHDYLLGNY PVGRDDAAQL CALQILVGIG FVNSPESCID WTSLLERFLP
460 470 480 490 500
RQIAITRAKR EWELDILARY RSMENVTKDD ARQQFLRILK ALPYGNSVFF
510 520 530 540 550
SVRKIDDPIG LLPGRIILGI NKRGVHFFRP VPKEYLHSAE LRDIMQFGSS
560 570 580 590 600
NTAVFFKMRV AGVLHIFQFE TKQGEEICVA LQTHINDVML RRYSKARSAA
610 620 630 640 650
NSLVNGDISC SSKPQNFEVY EKRLQDLSKA YEESQKKIEK LMDEQQEKNQ
660 670 680 690 700
QEVTLREELE AIHNGLELER RKLLEVTLDR DKLRSLCDEK GTTIQSLMSE
710 720 730 740 750
LRGMEARLAK SGNTKSSKET KSELAEMNNQ ILYKIQKELE VRNKELHVAV
760 770 780 790 800
DNSKRLLSEN KILEQNLNIE KKKKEEVEIH QKRYEQEKKV LKLRVSELEN
810 820 830 840 850
KLEVLAQDLD SAESTIESKN SDMLLLQNNL KELEELREMK EDIDRKNEQT
860 870 880 890 900
AAILKMQGAQ LAELEILYKE EQVLRKRYYN TIEDMKGKIR VYCRIRPLNE
910 920 930 940 950
KESSEREKQM LTTVDEFTVE HPWKDDKRKQ HIYDRVFDMR ASQDDIFEDT
960 970 980 990 1000
KYLVQSAVDG YNVCIFAYGQ TGSGKTFTIY GHESNPGLTP RATKELFNIL
1010 1020 1030 1040 1050
KRDSKRFSFS LKAYMVELYQ DTLVDLLLPK SARRLKLEIK KDSKGMVFVE
1060 1070 1080 1090 1100
NVTTIPISTL EELRMILERG SERRHVSGTN MNEESSRSHL ILSVVIESID
1110 1120 1130 1140 1150
LQTQSAARGK LSFVDLAGSE RVKKSGSAGC QLKEAQSINK SLSALGDVIG
1160 1170 1180 1190 1200
ALSSGNQHIP YRNHKLTMLM SDSLGGNAKT LMFVNVSPAE SNLDETYNSL
1210 1220 1230 1240 1250
LYASRVRTIV NDPSKHISSK EMVRLKKLVA YWKEQAGKKG EEEDLVDIEE
1260
DRTRKDEADS
Length:1,260
Mass (Da):143,449
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE6B562CAA6201EF
GO
Isoform 2 (identifier: Q9FHN8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     306-306: Missing.

Show »
Length:1,259
Mass (Da):143,320
Checksum:i95B41DF2B21BF26E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4JXM5F4JXM5_ARATH
Kinesin-like calmodulin-binding pro...
ZWI KCBP, PKCBP, ZWICHEL, At5g65930, K14B20.10
1,266Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti118D → IPI in AAC37475 (PubMed:8636137).Curated1
Sequence conflicti307 – 308EL → V in AAC37475 (PubMed:8636137).Curated2
Sequence conflicti415D → G in AAC37475 (PubMed:8636137).Curated1
Sequence conflicti588V → D in AAL36167 (PubMed:14593172).Curated1
Sequence conflicti602S → C in AAC49901 (PubMed:9434184).Curated1
Sequence conflicti611S → C in AAC49901 (PubMed:9434184).Curated1
Sequence conflicti693T → P in AAC49901 (PubMed:9434184).Curated1
Sequence conflicti922P → A in AAC49901 (PubMed:9434184).Curated1
Sequence conflicti977F → S in AAC37475 (PubMed:8636137).Curated1
Sequence conflicti1044K → T in AAC37475 (PubMed:8636137).Curated1
Sequence conflicti1085S → N in AAL36167 (PubMed:14593172).Curated1
Sequence conflicti1192N → D in AAL36167 (PubMed:14593172).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_040367306Missing in isoform 2. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
L40358 mRNA Translation: AAC37475.1
AF002220 Genomic DNA Translation: AAC49901.1
AF002678 Genomic DNA Translation: AAB61712.1
AB018108 Genomic DNA Translation: BAB11140.1
CP002688 Genomic DNA Translation: AED98125.1
CP002688 Genomic DNA Translation: AED98126.1
AY063811 mRNA Translation: AAL36167.1
AK229953 mRNA Translation: BAF01779.1

NCBI Reference Sequences

More...
RefSeqi
NP_569022.2, NM_125990.4 [Q9FHN8-1]
NP_851276.1, NM_180945.2 [Q9FHN8-2]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G65930.1; AT5G65930.1; AT5G65930 [Q9FHN8-2]
AT5G65930.2; AT5G65930.2; AT5G65930 [Q9FHN8-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
836723

Gramene; a comparative resource for plants

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Gramenei
AT5G65930.1; AT5G65930.1; AT5G65930 [Q9FHN8-2]
AT5G65930.2; AT5G65930.2; AT5G65930 [Q9FHN8-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT5G65930

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L40358 mRNA Translation: AAC37475.1
AF002220 Genomic DNA Translation: AAC49901.1
AF002678 Genomic DNA Translation: AAB61712.1
AB018108 Genomic DNA Translation: BAB11140.1
CP002688 Genomic DNA Translation: AED98125.1
CP002688 Genomic DNA Translation: AED98126.1
AY063811 mRNA Translation: AAL36167.1
AK229953 mRNA Translation: BAF01779.1
RefSeqiNP_569022.2, NM_125990.4 [Q9FHN8-1]
NP_851276.1, NM_180945.2 [Q9FHN8-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3H4SX-ray2.40A875-1260[»]
4FRZX-ray2.40A/B875-1260[»]
SMRiQ9FHN8
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi21965, 3 interactors
DIPiDIP-54846N
IntActiQ9FHN8, 8 interactors
STRINGi3702.AT5G65930.3

PTM databases

iPTMnetiQ9FHN8

Proteomic databases

PaxDbiQ9FHN8

Genome annotation databases

EnsemblPlantsiAT5G65930.1; AT5G65930.1; AT5G65930 [Q9FHN8-2]
AT5G65930.2; AT5G65930.2; AT5G65930 [Q9FHN8-1]
GeneIDi836723
GrameneiAT5G65930.1; AT5G65930.1; AT5G65930 [Q9FHN8-2]
AT5G65930.2; AT5G65930.2; AT5G65930 [Q9FHN8-1]
KEGGiath:AT5G65930

Organism-specific databases

AraportiAT5G65930

Phylogenomic databases

eggNOGiKOG0239 Eukaryota
KOG4229 Eukaryota
COG5059 LUCA
HOGENOMiHOG000241108
InParanoidiQ9FHN8
OrthoDBi364605at2759
PhylomeDBiQ9FHN8

Miscellaneous databases

EvolutionaryTraceiQ9FHN8

Protein Ontology

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PROi
PR:Q9FHN8

Gene expression databases

ExpressionAtlasiQ9FHN8 baseline and differential
GenevisibleiQ9FHN8 AT

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
Gene3Di1.20.80.10, 1 hit
1.25.40.530, 1 hit
2.30.29.30, 1 hit
3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR000299 FERM_domain
IPR018979 FERM_N
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR000857 MyTH4_dom
IPR038185 MyTH4_dom_sf
IPR027417 P-loop_NTPase
IPR011993 PH-like_dom_sf
IPR011254 Prismane-like_sf
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PF00225 Kinesin, 1 hit
PF00784 MyTH4, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM00129 KISc, 1 hit
SM00139 MyTH4, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF52540 SSF52540, 1 hit
SSF56821 SSF56821, 1 hit
PROSITEiView protein in PROSITE
PS50057 FERM_3, 1 hit
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
PS51016 MYTH4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKN14E_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9FHN8
Secondary accession number(s): O22326
, O23102, Q0WM77, Q39130, Q8VZV4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: March 1, 2001
Last modified: September 18, 2019
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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