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Protein
Submitted name:

Cadmium efflux ATPase CadA

Gene

cadA

Organism
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi17PROSITE-ProRule annotation1
Metal bindingi20PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cadmium efflux ATPase CadAImported
Submitted name:
Cadmium-transporting ATPaseImported
Gene namesi
Name:cadAImported
ORF Names:LMG9449_0628Imported, N42_1327Imported
Encoded oniPlasmid pAH82Imported
OrganismiLactococcus lactis subsp. lactis (Streptococcus lactis)Imported
Taxonomic identifieri1360 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeLactococcus
Proteomesi
  • UP000052991 Componenti: Unassembled WGS sequence
  • UP000053612 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei89 – 107HelicalUniRule annotationAdd BLAST19
Transmembranei315 – 335HelicalUniRule annotationAdd BLAST21
Transmembranei347 – 371HelicalUniRule annotationAdd BLAST25
Transmembranei654 – 674HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 60HMAInterPro annotationAdd BLAST54

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd00371 HMA, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 1 hit
PRINTSiPR00941 CDATPASE
SUPFAMiSSF55008 SSF55008, 1 hit
SSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9FB71-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEKMTEKTY RIEGLSCTNC AGKFEKNVKQ LPGVTSATVN FGASKISVEG
60 70 80 90 100
QTTIEELEEA GAFENLIIRD DQENDEQVRS KESFIKRNIA LIISLGFILV
110 120 130 140 150
AVISQLSLGE DHLLTKALYI LAIIIGGFDL FKEGFSDLIK LDFSMESLMT
160 170 180 190 200
IAIIGAAFIG EWAEGSIVVI LFAISEALER FSMDKARQSI RSLMDIAPKE
210 220 230 240 250
ALIRRNNVEQ LVSVDKIDID DIMIIKPGQK IAMDGLVING HSSVNQAAIT
260 270 280 290 300
GESVPVEKQL DDEVFAGTLN EEGVLEVKVT KKVTDTTIAK IIHLVEEAQG
310 320 330 340 350
ERAPAQAFVD KFAKYYTPFI IIMALLIVVV PPLFFGGDWN KWLYQGLSIL
360 370 380 390 400
VVGCPCSLVI STPVSIVSAI GNAAKNGVLV KGGVYLEEIG HLRAIAFDKT
410 420 430 440 450
GTLTKGKPVV TDFIATSSET DINYLSIISS LESLSQHPLA SAILNEADKT
460 470 480 490 500
NVDYKSIQIE DFQSITGKGL TGIHQNIRYY IGSPKLFSAS VIEETAVKVQ
510 520 530 540 550
YRQFQEQGKT AMYFGTDEQI LGVIAVADEV RDSSAAVISE LHKLSIEHTI
560 570 580 590 600
MLTGDNTKTA ESIGKQLGVT EIKGDLMPQE KLDSIKALRT TYNKVAMVGD
610 620 630 640 650
GINDAPALAA STVGIAMGGA GTDTALETAD VALMGDDLQK LPFIVRLSRQ
660 670 680 690 700
TLKVIKQNIT FSLGIKLLAL LLVIPGWLTL WIAIVADMGA TLLVTLNGLR

LMKVK
Length:705
Mass (Da):76,453
Last modified:March 1, 2001 - v1
Checksum:iEB9FE993C025DDE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF243383 Genomic DNA Translation: AAF98300.1
LKLS01000066 Genomic DNA Translation: KSU20408.1
LKLW01000079 Genomic DNA Translation: KSU27040.1
RefSeqiNP_862600.1, NC_004966.1
WP_001291323.1, NZ_OLME01000007.1

Genome annotation databases

EnsemblBacteriaiKSU20408; KSU20408; LMG9449_0628
KSU27040; KSU27040; N42_1327
GeneIDi3125821
PATRICifig|1360.108.peg.1469

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF243383 Genomic DNA Translation: AAF98300.1
LKLS01000066 Genomic DNA Translation: KSU20408.1
LKLW01000079 Genomic DNA Translation: KSU27040.1
RefSeqiNP_862600.1, NC_004966.1
WP_001291323.1, NZ_OLME01000007.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiKSU20408; KSU20408; LMG9449_0628
KSU27040; KSU27040; N42_1327
GeneIDi3125821
PATRICifig|1360.108.peg.1469

Family and domain databases

CDDicd00371 HMA, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 1 hit
PRINTSiPR00941 CDATPASE
SUPFAMiSSF55008 SSF55008, 1 hit
SSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ9FB71_LACLL
AccessioniPrimary (citable) accession number: Q9FB71
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: November 7, 2018
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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