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Protein

Beta-lactamase

Gene

blaUOE-1

Organism
Escherichia coli
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

A beta-lactam + H2O = a substituted beta-amino acid.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
Biological processAntibiotic resistanceUniRule annotationSAAS annotation

Protein family/group databases

MEROPSiS11.A01

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-lactamaseUniRule annotationSAAS annotation (EC:3.5.2.6UniRule annotationSAAS annotation)
Gene namesi
Name:blaUOE-1Imported
Synonyms:blaImported, bla CTX-M-15Imported, bla_2Imported, blaCTX-MImported, blaCTX-M-15Imported, blaCTX-M15Imported, CTX-M-15Imported
ORF Names:B1K96_05075Imported, BH694_26190Imported, BMR23_04260Imported, C6976_27555Imported, C6986_23925Imported, CA268_09065Imported, CA268_27315Imported, CRM83_00400Imported, ECONIH1_02760Imported, ECONIH1_27135Imported, MS6198_B109Imported
Encoded oniPlasmid IncF::A/CImported
Plasmid IncF::IncL/MImported
Plasmid p1002-1Imported
Plasmid p25104Imported
Plasmid pBP971-95Imported
Plasmid pC15-1aImported
Plasmid pCTX1929Imported
Plasmid pCTX913Imported
Plasmid pECO-824Imported
Plasmid pEK516Imported
Plasmid pESBL-12Imported
Plasmid pHNY2Imported
Plasmid pJIE098Imported
Plasmid pJIE100Imported
Plasmid pJIE101Imported
Plasmid pJIE118Imported
Plasmid pJIE134Imported
Plasmid pJIE143Imported
Plasmid pJIE186Imported
Plasmid pJIE250Imported
Plasmid pJIE286Imported
Plasmid pKC390Imported
Plasmid pKC404Imported
Plasmid pKC405Imported
Plasmid pKCT407Imported
Plasmid pMS6198BImported
Plasmid pMTE001Imported
Plasmid pYC-14Imported
Plasmid pYC-5bImported
Plasmid pblaCTX-M-11Imported
Plasmid pms6198bImported
Plasmid unnamedImported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000218424 Componenti: Unassembled WGS sequence
  • UP000238225 Componenti: Unassembled WGS sequence
  • UP000220282 Componenti: Unassembled WGS sequence
  • UP000094504 Componenti: Plasmid pms6198b
  • UP000239287 Componenti: Unassembled WGS sequence
  • UP000194331 Componenti: Plasmid p1002-1
  • UP000194285 Componenti: Unassembled WGS sequence
  • UP000030317 Componenti: Plasmid pECO-824
  • UP000243159 Componenti: Unassembled WGS sequence

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL6131
DrugBankiDB09060 Avibactam

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501529974829 – 291Beta-lactamaseSequence analysisAdd BLAST263

Structurei

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-A beta-lactamase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

KOiK18767
OMAiAMCSTSK

Family and domain databases

InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR000871 Beta-lactam_class-A
IPR023650 Beta-lactam_class-A_AS
PRINTSiPR00118 BLACTAMASEA
SUPFAMiSSF56601 SSF56601, 1 hit
PROSITEiView protein in PROSITE
PS00146 BETA_LACTAMASE_A, 1 hit

Sequencei

Sequence statusi: Complete.

Q9EXV5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKKSLRQFT LMATATVTLL LGSVPLYAQT ADVQQKLAEL ERQSGGRLGV
60 70 80 90 100
ALINTADNSQ ILYRADERFA MCSTSKVMAA AAVLKKSESE PNLLNQRVEI
110 120 130 140 150
KKSDLVNYNP IAEKHVNGTM SLAELSAAAL QYSDNVAMNK LIAHVGGPAS
160 170 180 190 200
VTAFARQLGD ETFRLDRTEP TLNTAIPGDP RDTTSPRAMA QTLRNLTLGK
210 220 230 240 250
ALGDSQRAQL VTWMKGNTTG AASIQAGLPA SWVVGDKTGS GGYGTTNDIA
260 270 280 290
VIWPKDRAPL ILVTYFTQPQ PKAESRRDVL ASAAKIVTDG L
Length:291
Mass (Da):31,144
Last modified:March 1, 2001 - v1
Checksum:i49C531A7D5607BA4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY013478 Genomic DNA Translation: AAG48377.1
AY044436 Genomic DNA Translation: AAL02127.1
AY458016 Genomic DNA Translation: AAR25032.1
AY462238 Genomic DNA Translation: AAR26004.1
AY463958 Genomic DNA Translation: AAR28032.1
AY604721 Genomic DNA Translation: AAT48020.1
AY604722 Genomic DNA Translation: AAT48025.1
AY960984 Genomic DNA Translation: AAY27811.1
DQ335219 Genomic DNA Translation: ABC73077.1
DQ485310 Genomic DNA Translation: ABE76830.1
DQ915953 Genomic DNA Translation: ABK06381.1
EU350510 Genomic DNA Translation: ABY66122.1
EU418920 Genomic DNA Translation: ACN58169.1
EU935738 Genomic DNA Translation: ACQ41904.1
GQ330540 Genomic DNA Translation: ACT85952.1
GQ274928 Genomic DNA Translation: ACV32734.1
GQ274932 Genomic DNA Translation: ACV32752.1
GQ274933 Genomic DNA Translation: ACV32754.1
GQ274935 Genomic DNA Translation: ACV32764.1
GQ385309 Genomic DNA Translation: ACX54236.1
HQ157353 Genomic DNA Translation: ADO16967.1
HQ157354 Genomic DNA Translation: ADO16970.1
HQ157355 Genomic DNA Translation: ADO16973.1
HQ157356 Genomic DNA Translation: ADO16976.1
HQ157357 Genomic DNA Translation: ADO16979.1
JN194214 Genomic DNA Translation: AEQ61756.1
EU418932 Genomic DNA Translation: AER36578.1
GU264003 Genomic DNA Translation: AER36586.1
EU418921 Genomic DNA Translation: AER36589.1
EU418922 Genomic DNA Translation: AER36602.1
EU418924 Genomic DNA Translation: AER36618.1
EU418925 Genomic DNA Translation: AER36624.1
EU418930 Genomic DNA Translation: AER36626.1
JQ318855 Genomic DNA Translation: AFH01005.1
JQ397655 Genomic DNA Translation: AFI26281.1
JQ397656 Genomic DNA Translation: AFI26284.1
JQ397658 Genomic DNA Translation: AFI26289.1
JQ397659 Genomic DNA Translation: AFI26292.1
JQ397660 Genomic DNA Translation: AFI26295.1
JQ397661 Genomic DNA Translation: AFI26298.1
JQ397662 Genomic DNA Translation: AFI26301.1
JQ397663 Genomic DNA Translation: AFI26304.1
JQ397667 Genomic DNA Translation: AFI26314.1
JX129216 Genomic DNA Translation: AFQ20795.1
JX129217 Genomic DNA Translation: AFQ20796.1
JX129218 Genomic DNA Translation: AFQ20797.1
JX129221 Genomic DNA Translation: AFQ20800.1
JX129222 Genomic DNA Translation: AFQ20801.1
KC817478 Genomic DNA Translation: AGR34004.1
KF155154 Genomic DNA Translation: AGY62865.1
KF155155 Genomic DNA Translation: AGY62869.1
KF155155 Genomic DNA Translation: AGY62870.1
KF155157 Genomic DNA Translation: AGY62877.1
KF155158 Genomic DNA Translation: AGY62880.1
KF155159 Genomic DNA Translation: AGY62884.1
KF155160 Genomic DNA Translation: AGY62889.1
KF155161 Genomic DNA Translation: AGY62895.1
KF601686 Genomic DNA Translation: AGZ85192.1
KJ533731 Genomic DNA Translation: AHZ64975.1
KJ533732 Genomic DNA Translation: AHZ64976.1
KJ533733 Genomic DNA Translation: AHZ64977.1
KJ533734 Genomic DNA Translation: AHZ64978.1
KJ533735 Genomic DNA Translation: AHZ64979.1
KJ533736 Genomic DNA Translation: AHZ64980.1
KJ533737 Genomic DNA Translation: AHZ64981.1
KJ533738 Genomic DNA Translation: AHZ64982.1
KJ533739 Genomic DNA Translation: AHZ64983.1
KJ533740 Genomic DNA Translation: AHZ64984.1
CP008735 Genomic DNA Translation: AIG72475.1
KF891471 Genomic DNA Translation: AIJ28670.1
CP009859 Genomic DNA Translation: AIX62232.1
CP009860 Genomic DNA Translation: AIX66880.1
CP015836 Genomic DNA Translation: AOM73348.1
CP021202 Genomic DNA Translation: ARR59549.1
CP021203 Genomic DNA Translation: ARR63004.1
AB683462 Genomic DNA Translation: BAM15698.1
AB683463 Genomic DNA Translation: BAM15702.1
AB683464 Genomic DNA Translation: BAM15704.1
AB683465 Genomic DNA Translation: BAM15706.1
AB701567 Genomic DNA Translation: BAM38180.1
AB701568 Genomic DNA Translation: BAM38185.1
AB701569 Genomic DNA Translation: BAM38189.1
AB701570 Genomic DNA Translation: BAM38193.1
AB701571 Genomic DNA Translation: BAM38196.1
AB701572 Genomic DNA Translation: BAM38201.1
AB701573 Genomic DNA Translation: BAM38205.1
AB976566 Genomic DNA Translation: BAP18770.1
AB976569 Genomic DNA Translation: BAP18779.1
AB976570 Genomic DNA Translation: BAP18782.1
AB976574 Genomic DNA Translation: BAP18795.1
AB976575 Genomic DNA Translation: BAP18799.1
AB976576 Genomic DNA Translation: BAP18801.1
AB976579 Genomic DNA Translation: BAP18811.1
AJ310929 Genomic DNA Translation: CAC84572.1
AM040706 Genomic DNA Translation: CAJ13638.1
FR828676 Genomic DNA Translation: CCA28537.1
HF549093 Genomic DNA Translation: CCO61930.1
HG798331 Genomic DNA Translation: CDL67816.1
NBCM01000004 Genomic DNA Translation: OTE94265.1
MJDL01000045 Genomic DNA Translation: PCM17486.1
PDEE01000001 Genomic DNA Translation: PEI02095.1
MPIB01000006 Genomic DNA Translation: PGF87705.1
PVPD01000118 Genomic DNA Translation: PSG53833.1
PVOT01000994 Genomic DNA Translation: PSG80696.1
RefSeqiNP_957562.1, NC_005327.1
WP_000239590.1, NZ_QBRW01000016.1
YP_003108206.1, NC_013121.1
YP_009061308.1, NC_024977.1

Genome annotation databases

EnsemblBacteriaiAIX62232; AIX62232; ECONIH1_02760
AIX66880; AIX66880; ECONIH1_27135
AOM73348; AOM73348; MS6198_B109
ODA89280; ODA89280; A9D65_00020
ODH15859; ODH15859; A6804_26620
ODH25949; ODH25949; A6803_25395
GeneIDi20468332
2716485
35548257
8319161
KEGGiag:AAL02127
PATRICifig|562.10474.peg.5733

Similar proteinsi

Entry informationi

Entry nameiQ9EXV5_ECOLX
AccessioniPrimary (citable) accession number: Q9EXV5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2001
Last sequence update: March 1, 2001
Last modified: July 18, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported, PlasmidImported

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