Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 129 (26 Feb 2020)
Sequence version 2 (27 Jul 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Eukaryotic translation initiation factor 4E transporter

Gene

Eif4enif1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nucleoplasmic shuttling protein, which inhibits translation initiation. Mediates the nuclear import of EIF4E by a piggy-back mechanism.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Eukaryotic translation initiation factor 4E transporter
Short name:
4E-T
Short name:
eIF4E transporter
Alternative name(s):
Eukaryotic translation initiation factor 4E nuclear import factor 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Eif4enif1
Synonyms:Clast4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1921453 Eif4enif1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000643821 – 983Eukaryotic translation initiation factor 4E transporterAdd BLAST983

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei4PhosphoserineBy similarity1
Modified residuei73PhosphoserineBy similarity1
Modified residuei77PhosphoserineBy similarity1
Modified residuei114PhosphoserineBy similarity1
Modified residuei119PhosphoserineBy similarity1
Modified residuei135PhosphoserineBy similarity1
Modified residuei137PhosphoserineBy similarity1
Modified residuei300PhosphoserineBy similarity1
Modified residuei344PhosphoserineBy similarity1
Modified residuei352PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki409Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei416PhosphoserineBy similarity1
Modified residuei485N6-acetyllysineBy similarity1
Modified residuei563PhosphoserineCombined sources1
Modified residuei586PhosphoserineCombined sources1
Modified residuei692PhosphoserineBy similarity1
Modified residuei919PhosphoserineBy similarity1
Modified residuei949PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9EST3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9EST3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9EST3

PeptideAtlas

More...
PeptideAtlasi
Q9EST3

PRoteomics IDEntifications database

More...
PRIDEi
Q9EST3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9EST3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9EST3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000020454 Expressed in dorsal pancreas and 275 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9EST3 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9EST3 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with EIF4E.

Interacts with importin beta only in the presence of importin alpha, suggesting a direct interaction with importin alpha.

Interacts with APOBEC3G in an RNA-dependent manner.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
216574, 6 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000105676

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9EST3 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9EST3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni29 – 35EIF4E-bindingBy similarity7

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi194 – 210Nuclear localization signalBy similarityAdd BLAST17
Motifi437 – 446Nuclear export signalBy similarity10
Motifi612 – 637Nuclear export signalBy similarityAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi147 – 209Arg-richAdd BLAST63

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IG0J Eukaryota
ENOG41110MN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012071

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_014394_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9EST3

KEGG Orthology (KO)

More...
KOi
K18728

Identification of Orthologs from Complete Genome Data

More...
OMAi
NQRPNED

Database of Orthologous Groups

More...
OrthoDBi
198628at2759

TreeFam database of animal gene trees

More...
TreeFami
TF101531

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018862 eIF4E-T

The PANTHER Classification System

More...
PANTHERi
PTHR12269 PTHR12269, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10477 EIF4E-T, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9EST3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEKSVAETEN GDAFLELKKL PTSKSPHRYT KEELLDIKER PYSKQRPSCL
60 70 80 90 100
SEKYDSDGVW DPEKWHASLY PASGRSSPVE SLKKESESDR PSLVRRIADP
110 120 130 140 150
RERVKEDDLD VVLSPQRRSF GGGCHVTAAV SSRRSGSPLE KDSDGLRLLG
160 170 180 190 200
GRRIGSGRII SARAFEKDHR LSDKDLRDLR DRDRERDYKD KRFRREFGDS
210 220 230 240 250
KRVFGERRRN DSYTEEEPEW FSAGPTSQSE TIELTGFDDK ILEEDHKGRK
260 270 280 290 300
RTRRRTASVK EGIVECNGGV AEEDEVEVIL AQEPSADQEV PRDVILPEQS
310 320 330 340 350
PGEFDFNEFF NLDKVPCLAS MIEDVLGEGS VSASRFSRWF SNPSRSGSRS
360 370 380 390 400
SSLGSTPHEE LERLAGLEQA VLSPGQNSGN YFAPIPSEDH AENKVDILEM
410 420 430 440 450
LQKAKVDLKP LLSSLSANKE KLKESSHSGV VLSVEEVEAG LKGLKVDQQM
460 470 480 490 500
KNSTPFMAEH LEETLSAASS NRQLKKDGDM TAFNKLVNTM KASGTLPTQP
510 520 530 540 550
KVSRNVESHL LAPAEIPGQP VSKNILQELL GQPVQRPASS NLLSGLMGSL
560 570 580 590 600
EATASLLSQR APSPPMSQVF RTQAASADYL HPRIPSPIGF PSGPQQLLGD
610 620 630 640 650
PFQGMRKPMS PVSAQMSQLE LQQAALEGLA LPHDLAVQTA PFYQPGFSKP
660 670 680 690 700
QVDRTRDGLR NRQQRMSKSP APMHGGNSSS PAPAASITSM LSPSFTPTSV
710 720 730 740 750
IRKMYESREK TKEEMAPGMV VPGDGKEDTQ KTSEENLLSS NPIPNTDQDS
760 770 780 790 800
STTNPKLSTL QRSSCSTPLS QTSRYTKEQD YRPKTAGRKT PTLASPVPGT
810 820 830 840 850
PFLRPTHQVP LVPHVPIVRP AHQLHPGLVQ RLIAQGVHPQ HLPSLLQAGV
860 870 880 890 900
LPPGIDMAPL QGLSGPLLGQ PLYPLVSAAS HPLLNPRPGT PLHLAVMQQQ
910 920 930 940 950
LQRSVLHPPG SSSQAAAISV QTPQNVPSRS GMPHMHSQLE HRTSQRSSSP
960 970 980
VGLAKWFGSD VLQQPLPSMP TKVISVDELE YRQ
Length:983
Mass (Da):107,986
Last modified:July 27, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC010A10376699DA8
GO
Isoform 2 (identifier: Q9EST3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     504-527: Missing.

Show »
Length:959
Mass (Da):105,393
Checksum:i8B4CC73C34EB492C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5NBZ7Q5NBZ7_MOUSE
Eukaryotic translation initiation f...
Eif4enif1
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8Y5K6A8Y5K6_MOUSE
Eukaryotic translation initiation f...
Eif4enif1
808Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5NBZ4Q5NBZ4_MOUSE
Eukaryotic translation initiation f...
Eif4enif1
239Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti345R → Q in BAB11963 (Ref. 1) Curated1
Sequence conflicti773S → N in BAB11963 (Ref. 1) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_003785504 – 527Missing in isoform 2. 1 PublicationAdd BLAST24

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB031388 mRNA Translation: BAB11963.1
AL671968 Genomic DNA No translation available.
CH466574 Genomic DNA Translation: EDL40398.1
BC033410 mRNA Translation: AAH33410.1
AK012082 mRNA Translation: BAB28016.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS24354.1 [Q9EST3-1]
CCDS48739.1 [Q9EST3-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001160019.1, NM_001166547.1 [Q9EST3-1]
NP_001160020.1, NM_001166548.1 [Q9EST3-2]
NP_001160021.1, NM_001166549.1 [Q9EST3-2]
NP_076232.2, NM_023743.2 [Q9EST3-1]
XP_006514904.1, XM_006514841.2 [Q9EST3-1]
XP_006514905.1, XM_006514842.3 [Q9EST3-1]
XP_006514906.1, XM_006514843.3 [Q9EST3-1]
XP_006514907.1, XM_006514844.2 [Q9EST3-2]
XP_017170295.1, XM_017314806.1 [Q9EST3-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000020734; ENSMUSP00000020734; ENSMUSG00000020454 [Q9EST3-2]
ENSMUST00000110049; ENSMUSP00000105676; ENSMUSG00000020454 [Q9EST3-1]
ENSMUST00000110048; ENSMUSP00000105675; ENSMUSG00000020454 [Q9EST3-2]
ENSMUST00000179770; ENSMUSP00000136768; ENSMUSG00000020454 [Q9EST3-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
74203

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:74203

UCSC genome browser

More...
UCSCi
uc007hsc.2 mouse [Q9EST3-2]
uc007hse.2 mouse [Q9EST3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB031388 mRNA Translation: BAB11963.1
AL671968 Genomic DNA No translation available.
CH466574 Genomic DNA Translation: EDL40398.1
BC033410 mRNA Translation: AAH33410.1
AK012082 mRNA Translation: BAB28016.1
CCDSiCCDS24354.1 [Q9EST3-1]
CCDS48739.1 [Q9EST3-2]
RefSeqiNP_001160019.1, NM_001166547.1 [Q9EST3-1]
NP_001160020.1, NM_001166548.1 [Q9EST3-2]
NP_001160021.1, NM_001166549.1 [Q9EST3-2]
NP_076232.2, NM_023743.2 [Q9EST3-1]
XP_006514904.1, XM_006514841.2 [Q9EST3-1]
XP_006514905.1, XM_006514842.3 [Q9EST3-1]
XP_006514906.1, XM_006514843.3 [Q9EST3-1]
XP_006514907.1, XM_006514844.2 [Q9EST3-2]
XP_017170295.1, XM_017314806.1 [Q9EST3-2]

3D structure databases

SMRiQ9EST3
ModBaseiSearch...

Protein-protein interaction databases

BioGridi216574, 6 interactors
STRINGi10090.ENSMUSP00000105676

PTM databases

iPTMnetiQ9EST3
PhosphoSitePlusiQ9EST3

Proteomic databases

EPDiQ9EST3
jPOSTiQ9EST3
PaxDbiQ9EST3
PeptideAtlasiQ9EST3
PRIDEiQ9EST3

Genome annotation databases

EnsembliENSMUST00000020734; ENSMUSP00000020734; ENSMUSG00000020454 [Q9EST3-2]
ENSMUST00000110049; ENSMUSP00000105676; ENSMUSG00000020454 [Q9EST3-1]
ENSMUST00000110048; ENSMUSP00000105675; ENSMUSG00000020454 [Q9EST3-2]
ENSMUST00000179770; ENSMUSP00000136768; ENSMUSG00000020454 [Q9EST3-1]
GeneIDi74203
KEGGimmu:74203
UCSCiuc007hsc.2 mouse [Q9EST3-2]
uc007hse.2 mouse [Q9EST3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56478
MGIiMGI:1921453 Eif4enif1

Phylogenomic databases

eggNOGiENOG410IG0J Eukaryota
ENOG41110MN LUCA
GeneTreeiENSGT00390000012071
HOGENOMiCLU_014394_0_0_1
InParanoidiQ9EST3
KOiK18728
OMAiNQRPNED
OrthoDBi198628at2759
TreeFamiTF101531

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Eif4enif1 mouse

Protein Ontology

More...
PROi
PR:Q9EST3
RNActiQ9EST3 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000020454 Expressed in dorsal pancreas and 275 other tissues
ExpressionAtlasiQ9EST3 baseline and differential
GenevisibleiQ9EST3 MM

Family and domain databases

InterProiView protein in InterPro
IPR018862 eIF4E-T
PANTHERiPTHR12269 PTHR12269, 1 hit
PfamiView protein in Pfam
PF10477 EIF4E-T, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry namei4ET_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9EST3
Secondary accession number(s): Q8CFW0, Q9CSS3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: July 27, 2011
Last modified: February 26, 2020
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again