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Entry version 138 (29 Sep 2021)
Sequence version 3 (01 Oct 2002)
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Protein

Ubiquitin-protein ligase E3B

Gene

Ube3b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1038Glycyl thioester intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-983168, Antigen processing: Ubiquitination & Proteasome degradation

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubiquitin-protein ligase E3B (EC:2.3.2.26)
Alternative name(s):
HECT-type ubiquitin transferase E3B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ube3b
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1891295, Ube3b

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000029577

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002818831 – 1070Ubiquitin-protein ligase E3BAdd BLAST1070

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei421PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ES34

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9ES34

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ES34

PeptideAtlas

More...
PeptideAtlasi
Q9ES34

PRoteomics IDEntifications database

More...
PRIDEi
Q9ES34

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
297787

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ES34

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ES34

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9ES34

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed. High expression is observed in developing central nervous system.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029577, Expressed in hindlimb stylopod muscle and 322 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ES34, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
228169, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000073652

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9ES34, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ES34

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 58IQPROSITE-ProRule annotationAdd BLAST30
Domaini704 – 1070HECTPROSITE-ProRule annotationAdd BLAST367

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4427, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156548

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002173_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ES34

Identification of Orthologs from Complete Genome Data

More...
OMAi
PNHWLIP

Database of Orthologous Groups

More...
OrthoDBi
1163565at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ES34

TreeFam database of animal gene trees

More...
TreeFami
TF313215

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00078, HECTc, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR044611, E3B/C
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR000048, IQ_motif_EF-hand-BS

The PANTHER Classification System

More...
PANTHERi
PTHR45700, PTHR45700, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00632, HECT, 1 hit
PF00612, IQ, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00119, HECTc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56204, SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50237, HECT, 1 hit
PS50096, IQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9ES34-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFTVSQTSRA WFIDRARQAR EERLVQKERE RSAVTIQALV RSFLCRRRLH
60 70 80 90 100
RDIRKEIDEF FSADESGSSK RSALCIFKIA RRLLFICKTT EDSERLEKLC
110 120 130 140 150
RSILNSMDAE NEPKVWYVSL ALSKDLTLLW IKQIKSILWH CCELLGQLKP
160 170 180 190 200
EILQDSRLIT LYLTMLVTFT DTSTWKILRG KGESLRPALN HICANIMGHL
210 220 230 240 250
NQRGLYSVLQ VLLTRGLARP RPCLSKGMLT AAFSLALRPV VAAQFSDNLM
260 270 280 290 300
RPFIIHVMSV PALVAHLSTV APERLGVLES HDMLRKFIVF LRDRDRCRDA
310 320 330 340 350
CESLEGCHTL CLMGNLLHLG SLSLRLLEEE MDGFVSALTQ MLCYCQKYVA
360 370 380 390 400
QKKSNLTHWH PVLGWFSQPV DYGLNDSMYL ITKQLQFLWA VPLIRILFSD
410 420 430 440 450
ILSRKLLEHA EPAPVQPQPS SPQTVLPVKS LLKRAFQKSA SVRNILRPVG
460 470 480 490 500
GRRVDSAEVR KVCNICVLYQ TSLTTLTQIR LQILTGLTYL DDLLPKLWAF
510 520 530 540 550
ICELGPHGGL KLFLECLNND TGESKQLLAM LMLFCDCSRH LITILDDIEV
560 570 580 590 600
YEEQISFKLE ELVTISSFLN SFVFKMIWDG IVENAKGETL ELFQSVHGWL
610 620 630 640 650
MVLYERDCRR RFAPEDHWLR RDLKPGVLFQ ELDKDRRRAQ LVLQHIPHVV
660 670 680 690 700
PHKNRVLLFR NMVIKEKEKL GLVETSSASP HVTHITIRRS RMLEDGYEQL
710 720 730 740 750
RQLSQHAMKG VIRVKFVNDL GVDEAGIDQD GVFKEFLEEI IKRVFDPALN
760 770 780 790 800
LFKTTSGDER LYPSPTSYIH ENYLQLFEFV GKMLGKAVYE GIVVDVPFAS
810 820 830 840 850
FFLSQMLGHH HSVFYSSVDE LPSLDSEFYK NLTSIKRYDG DIADLGLTLS
860 870 880 890 900
YDEDVMGQLV CHELVPGGKT IPVTDENKIS YIHLMAHFRM HTQIKNQTAA
910 920 930 940 950
LISGFRSIIK PEWIRMFSTP ELQRLISGDN AEIDLEDLKK HTVYYGGFHG
960 970 980 990 1000
SHRVIIWLWD ILASDFTPEE RAMFLKFVTS CSRPPLLGFA YLKPPFSIRC
1010 1020 1030 1040 1050
VEVSDDQDTG DTLGSVLRGF FTIRKREPGG RLPTSSTCFN LLKLPNYSKK
1060 1070
SVLREKLRYA ISMNTGFELS
Length:1,070
Mass (Da):122,762
Last modified:October 1, 2002 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAEC9A7F4232A434E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
S4R2P2S4R2P2_MOUSE
HECT-type E3 ubiquitin transferase
Ube3b
243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JG76A0A0G2JG76_MOUSE
HECT-type E3 ubiquitin transferase
Ube3b
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JEX8A0A0G2JEX8_MOUSE
Ubiquitin-protein ligase E3B
Ube3b
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH34059 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF244362 mRNA Translation: AAG16783.3
BC023956 mRNA Translation: AAH23956.1
BC034059 mRNA Translation: AAH34059.1 Different initiation.
BC096743 mRNA Translation: AAH96743.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS19564.1

NCBI Reference Sequences

More...
RefSeqi
NP_473434.2, NM_054093.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000074002; ENSMUSP00000073652; ENSMUSG00000029577

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
117146

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:117146

UCSC genome browser

More...
UCSCi
uc008yzn.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF244362 mRNA Translation: AAG16783.3
BC023956 mRNA Translation: AAH23956.1
BC034059 mRNA Translation: AAH34059.1 Different initiation.
BC096743 mRNA Translation: AAH96743.1
CCDSiCCDS19564.1
RefSeqiNP_473434.2, NM_054093.3

3D structure databases

SMRiQ9ES34
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi228169, 3 interactors
STRINGi10090.ENSMUSP00000073652

PTM databases

iPTMnetiQ9ES34
PhosphoSitePlusiQ9ES34
SwissPalmiQ9ES34

Proteomic databases

EPDiQ9ES34
MaxQBiQ9ES34
PaxDbiQ9ES34
PeptideAtlasiQ9ES34
PRIDEiQ9ES34
ProteomicsDBi297787

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
30872, 76 antibodies

The DNASU plasmid repository

More...
DNASUi
117146

Genome annotation databases

EnsembliENSMUST00000074002; ENSMUSP00000073652; ENSMUSG00000029577
GeneIDi117146
KEGGimmu:117146
UCSCiuc008yzn.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
89910
MGIiMGI:1891295, Ube3b
VEuPathDBiHostDB:ENSMUSG00000029577

Phylogenomic databases

eggNOGiKOG4427, Eukaryota
GeneTreeiENSGT00940000156548
HOGENOMiCLU_002173_2_0_1
InParanoidiQ9ES34
OMAiPNHWLIP
OrthoDBi1163565at2759
PhylomeDBiQ9ES34
TreeFamiTF313215

Enzyme and pathway databases

UniPathwayiUPA00143
ReactomeiR-MMU-983168, Antigen processing: Ubiquitination & Proteasome degradation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
117146, 0 hits in 61 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ube3b, mouse

Protein Ontology

More...
PROi
PR:Q9ES34
RNActiQ9ES34, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000029577, Expressed in hindlimb stylopod muscle and 322 other tissues
GenevisibleiQ9ES34, MM

Family and domain databases

CDDicd00078, HECTc, 1 hit
InterProiView protein in InterPro
IPR044611, E3B/C
IPR000569, HECT_dom
IPR035983, Hect_E3_ubiquitin_ligase
IPR000048, IQ_motif_EF-hand-BS
PANTHERiPTHR45700, PTHR45700, 1 hit
PfamiView protein in Pfam
PF00632, HECT, 1 hit
PF00612, IQ, 1 hit
SMARTiView protein in SMART
SM00119, HECTc, 1 hit
SUPFAMiSSF56204, SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50237, HECT, 1 hit
PS50096, IQ, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBE3B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ES34
Secondary accession number(s): Q8K068
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: October 1, 2002
Last modified: September 29, 2021
This is version 138 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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