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Protein

Probable ergosterol biosynthetic protein 28

Gene

Erg28

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • protein binding, bridging Source: GO_Central

GO - Biological processi

Keywordsi

Biological processLipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ergosterol biosynthetic protein 28
Gene namesi
Name:Erg28Imported
Synonyms:Orf11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1915571 Erg28

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei52 – 72HelicalSequence analysisAdd BLAST21
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Transmembranei105 – 125HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001939041 – 140Probable ergosterol biosynthetic protein 28Add BLAST140

Proteomic databases

EPDiQ9ERY9
MaxQBiQ9ERY9
PaxDbiQ9ERY9
PeptideAtlasiQ9ERY9
PRIDEiQ9ERY9

PTM databases

PhosphoSitePlusiQ9ERY9
SwissPalmiQ9ERY9

Expressioni

Gene expression databases

BgeeiENSMUSG00000021252 Expressed in 261 organ(s), highest expression level in liver
CleanExiMM_0610007P14RIK
ExpressionAtlasiQ9ERY9 baseline and differential
GenevisibleiQ9ERY9 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021676

Family & Domainsi

Sequence similaritiesi

Belongs to the ERG28 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3455 Eukaryota
ENOG4111J9X LUCA
GeneTreeiENSGT00390000010925
HOGENOMiHOG000164093
HOVERGENiHBG051505
InParanoidiQ9ERY9
OMAiIIRCACA
OrthoDBiEOG091G16N5
PhylomeDBiQ9ERY9
TreeFamiTF300191

Family and domain databases

InterProiView protein in InterPro
IPR005352 Erg28
PANTHERiPTHR15451 PTHR15451, 1 hit
PfamiView protein in Pfam
PF03694 Erg28, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9ERY9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRFLNVLRS WLVMVSIIAM GNTLQSFRDH TFLYEKLYTG KPNLVNGLQA
60 70 80 90 100
RTFGIWTLLS SVIRCLCAID IHNKTLYHIT LWTFLLALGH FLSELFVFGT
110 120 130 140
AAPTVGVLAP LMVASFSILG MLVGLRYLEA EPVSRQKKRN
Length:140
Mass (Da):15,806
Last modified:March 1, 2001 - v1
Checksum:iBDD082A4916E9E50
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YUR8D3YUR8_MOUSE
Probable ergosterol biosynthetic pr...
Erg28 0610007P14Rik
54Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF270646 mRNA Translation: AAG17664.1
AK004480 mRNA Translation: BAB23325.1
AK152230 mRNA Translation: BAE31057.1
BC004591 mRNA Translation: AAH04591.1
CCDSiCCDS26063.1
RefSeqiNP_067421.1, NM_021446.2
XP_006516180.1, XM_006516117.2
UniGeneiMm.143795

Genome annotation databases

EnsembliENSMUST00000021676; ENSMUSP00000021676; ENSMUSG00000021252
GeneIDi58520
KEGGimmu:58520
UCSCiuc007ohf.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF270646 mRNA Translation: AAG17664.1
AK004480 mRNA Translation: BAB23325.1
AK152230 mRNA Translation: BAE31057.1
BC004591 mRNA Translation: AAH04591.1
CCDSiCCDS26063.1
RefSeqiNP_067421.1, NM_021446.2
XP_006516180.1, XM_006516117.2
UniGeneiMm.143795

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021676

PTM databases

PhosphoSitePlusiQ9ERY9
SwissPalmiQ9ERY9

Proteomic databases

EPDiQ9ERY9
MaxQBiQ9ERY9
PaxDbiQ9ERY9
PeptideAtlasiQ9ERY9
PRIDEiQ9ERY9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021676; ENSMUSP00000021676; ENSMUSG00000021252
GeneIDi58520
KEGGimmu:58520
UCSCiuc007ohf.1 mouse

Organism-specific databases

CTDi11161
MGIiMGI:1915571 Erg28

Phylogenomic databases

eggNOGiKOG3455 Eukaryota
ENOG4111J9X LUCA
GeneTreeiENSGT00390000010925
HOGENOMiHOG000164093
HOVERGENiHBG051505
InParanoidiQ9ERY9
OMAiIIRCACA
OrthoDBiEOG091G16N5
PhylomeDBiQ9ERY9
TreeFamiTF300191

Miscellaneous databases

PROiPR:Q9ERY9
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021252 Expressed in 261 organ(s), highest expression level in liver
CleanExiMM_0610007P14RIK
ExpressionAtlasiQ9ERY9 baseline and differential
GenevisibleiQ9ERY9 MM

Family and domain databases

InterProiView protein in InterPro
IPR005352 Erg28
PANTHERiPTHR15451 PTHR15451, 1 hit
PfamiView protein in Pfam
PF03694 Erg28, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiERG28_MOUSE
AccessioniPrimary (citable) accession number: Q9ERY9
Secondary accession number(s): Q3U8G1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: March 1, 2001
Last modified: November 7, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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