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Entry version 154 (29 Sep 2021)
Sequence version 2 (10 May 2004)
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Protein

Cysteine--tRNA ligase, cytoplasmic

Gene

Cars1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).

By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi138ZincBy similarity1
Metal bindingi431ZincBy similarity1
Metal bindingi456ZincBy similarity1
Metal bindingi460ZincBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei492ATPBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cysteine--tRNA ligase, cytoplasmic (EC:6.1.1.16By similarity)
Alternative name(s):
Cysteinyl-tRNA synthetase
Short name:
CysRS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cars1
Synonyms:Cars
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1351477, Cars

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000010755

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001595512 – 831Cysteine--tRNA ligase, cytoplasmicAdd BLAST830

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei102PhosphoserineCombined sources1
Modified residuei388PhosphoserineBy similarity1
Modified residuei390PhosphoserineCombined sources1
Modified residuei829PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9ER72

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9ER72

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9ER72

PeptideAtlas

More...
PeptideAtlasi
Q9ER72

PRoteomics IDEntifications database

More...
PRIDEi
Q9ER72

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
258681 [Q9ER72-1]
258682 [Q9ER72-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9ER72

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9ER72

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9ER72

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000010755, Expressed in lens of camera-type eye and 316 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9ER72, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
205152, 16 interactors

Molecular INTeraction database

More...
MINTi
Q9ER72

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000010899

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9ER72, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9ER72

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni736 – 766DisorderedSequence analysisAdd BLAST31

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi140 – 150'HIGH' regionAdd BLAST11
Motifi489 – 493'KMSKS' region5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi736 – 762Basic and acidic residuesSequence analysisAdd BLAST27

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1668, Eukaryota
KOG2007, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006347

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013528_3_3_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9ER72

Identification of Orthologs from Complete Genome Data

More...
OMAi
FHNDMKS

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9ER72

TreeFam database of animal gene trees

More...
TreeFami
TF300384

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00672, CysRS_core, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00041, Cys_tRNA_synth, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015803, Cys-tRNA-ligase
IPR024909, Cys-tRNA/MSH_ligase
IPR036282, Glutathione-S-Trfase_C_sf
IPR032678, tRNA-synt_1_cat_dom
IPR009080, tRNAsynth_Ia_anticodon-bd

The PANTHER Classification System

More...
PANTHERi
PTHR10890, PTHR10890, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01406, tRNA-synt_1e, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00983, TRNASYNTHCYS

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47323, SSF47323, 1 hit
SSF47616, SSF47616, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00435, cysS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9ER72-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAGSSAEQAA DYRSILSISD EAARVQALDQ HLSTRSYIQG YSLSQADVDV
60 70 80 90 100
FRQLSAPPAD SRLFHVARWF RHIEALLGGP QGRDEPCRLQ ASKGRRVQPQ
110 120 130 140 150
WSPPAGTEPC RLRLYNSLTR NKDVFIPQDG KKVTWYCCGP TVYDASHMGH
160 170 180 190 200
ARSYISFDIL RRVLRDYFQY DVFYCMNITD IDDKIIRRAR QNYLFEQYRE
210 220 230 240 250
QKPPATQLLK DVRDAMKPFS VKLSETTDPD KRQMLERIQN SVKLATEPLE
260 270 280 290 300
QAVRSSLSGE EVDSKVQVLL EEAKDLLSDW LDSTGGSEVT DNSIFSKLPK
310 320 330 340 350
FWEEEFHKDM EALNVLPPDV LTRVSEYVPE IVNFVQKIVD NGYGYASNGS
360 370 380 390 400
VYFDTAKFAA SEKHSYGKLV PEAVGDQKAL QEGEGDLSIS ADRLSEKRSP
410 420 430 440 450
NDFALWKASK PGEPSWPCPW GKGRPGWHIE CSAMAGTLLG ASMDIHGGGF
460 470 480 490 500
DLRFPHHDNE LAQSEAYFEN DCWVRYFLHT GHLTIAGCKM SKSLKNFITI
510 520 530 540 550
KDALKKHSAR QLRLAFLMHS WKDTLDYSSN TMESALQYEK FMNEFFLNVK
560 570 580 590 600
DILRAPVDIT GQFEKWEAEE VELNKNFYGK KTAVHEALCD NIDTRTVMEE
610 620 630 640 650
MRALVSQCNL YMAARKAERR RPNRALLENI AMYLTHMLKI FGAIEEESPL
660 670 680 690 700
GFPVGGPGTN LNLESTVMPY LQVLSEFREG VRKIAREKKV LEVLQLSDAL
710 720 730 740 750
RDDILPELGV RFEDHEGLPT VVKLVDRDTL LKEKEGKKRA EEEKRRKKEE
760 770 780 790 800
AARKKQEQEA AKLAKMKIPP SEMFLSEVNK YSKFDENGLP THDTEGKELS
810 820 830
KGQAKKLKKL FEAQEKLYKE YLQMLQNGSL Q
Length:831
Mass (Da):94,860
Last modified:May 10, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5FE338D27AE32B92
GO
Isoform 2 (identifier: Q9ER72-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     9-92: AADYRSILSI...RDEPCRLQAS → G

Show »
Length:748
Mass (Da):85,551
Checksum:i48E21E753893755E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A140LIB6A0A140LIB6_MOUSE
Cysteinyl-tRNA synthetase
Cars
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LII7A0A140LII7_MOUSE
Cysteinyl-tRNA synthetase
Cars
39Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti161R → P in AAH30473 (PubMed:15489334).Curated1
Sequence conflicti164L → R in AAH30473 (PubMed:15489334).Curated1
Sequence conflicti310M → K in BAC28234 (PubMed:16141072).Curated1
Sequence conflicti313L → P in BAA29032 (Ref. 4) Curated1
Sequence conflicti742E → G in BAC28234 (PubMed:16141072).Curated1
Sequence conflicti771S → G in CAC16398 (PubMed:11063728).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0102589 – 92AADYR…RLQAS → G in isoform 2. 1 PublicationAdd BLAST84

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ276505 Genomic DNA Translation: CAC16398.1
AJ276796 mRNA Translation: CAC16403.1
AK033328 mRNA Translation: BAC28234.1
AK037227 mRNA Translation: BAC29766.1
AK077558 mRNA Translation: BAC36862.1
BC030473 mRNA Translation: AAH30473.1
BC054717 mRNA Translation: AAH54717.1
BC058954 mRNA Translation: AAH58954.1
AB015589 mRNA Translation: BAA29032.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS40198.1 [Q9ER72-1]
CCDS57597.1 [Q9ER72-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001239522.1, NM_001252593.1 [Q9ER72-2]
NP_038770.3, NM_013742.5 [Q9ER72-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000010899; ENSMUSP00000010899; ENSMUSG00000010755 [Q9ER72-1]
ENSMUST00000105909; ENSMUSP00000101529; ENSMUSG00000010755 [Q9ER72-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
27267

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:27267

UCSC genome browser

More...
UCSCi
uc009kpn.2, mouse [Q9ER72-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ276505 Genomic DNA Translation: CAC16398.1
AJ276796 mRNA Translation: CAC16403.1
AK033328 mRNA Translation: BAC28234.1
AK037227 mRNA Translation: BAC29766.1
AK077558 mRNA Translation: BAC36862.1
BC030473 mRNA Translation: AAH30473.1
BC054717 mRNA Translation: AAH54717.1
BC058954 mRNA Translation: AAH58954.1
AB015589 mRNA Translation: BAA29032.1
CCDSiCCDS40198.1 [Q9ER72-1]
CCDS57597.1 [Q9ER72-2]
RefSeqiNP_001239522.1, NM_001252593.1 [Q9ER72-2]
NP_038770.3, NM_013742.5 [Q9ER72-1]

3D structure databases

SMRiQ9ER72
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi205152, 16 interactors
MINTiQ9ER72
STRINGi10090.ENSMUSP00000010899

PTM databases

iPTMnetiQ9ER72
PhosphoSitePlusiQ9ER72
SwissPalmiQ9ER72

Proteomic databases

EPDiQ9ER72
jPOSTiQ9ER72
PaxDbiQ9ER72
PeptideAtlasiQ9ER72
PRIDEiQ9ER72
ProteomicsDBi258681 [Q9ER72-1]
258682 [Q9ER72-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1044, 234 antibodies

The DNASU plasmid repository

More...
DNASUi
27267

Genome annotation databases

EnsembliENSMUST00000010899; ENSMUSP00000010899; ENSMUSG00000010755 [Q9ER72-1]
ENSMUST00000105909; ENSMUSP00000101529; ENSMUSG00000010755 [Q9ER72-2]
GeneIDi27267
KEGGimmu:27267
UCSCiuc009kpn.2, mouse [Q9ER72-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
27267
MGIiMGI:1351477, Cars
VEuPathDBiHostDB:ENSMUSG00000010755

Phylogenomic databases

eggNOGiKOG1668, Eukaryota
KOG2007, Eukaryota
GeneTreeiENSGT00390000006347
HOGENOMiCLU_013528_3_3_1
InParanoidiQ9ER72
OMAiFHNDMKS
PhylomeDBiQ9ER72
TreeFamiTF300384

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
27267, 21 hits in 63 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Cars, mouse

Protein Ontology

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PROi
PR:Q9ER72
RNActiQ9ER72, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000010755, Expressed in lens of camera-type eye and 316 other tissues
GenevisibleiQ9ER72, MM

Family and domain databases

CDDicd00672, CysRS_core, 1 hit
HAMAPiMF_00041, Cys_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR015803, Cys-tRNA-ligase
IPR024909, Cys-tRNA/MSH_ligase
IPR036282, Glutathione-S-Trfase_C_sf
IPR032678, tRNA-synt_1_cat_dom
IPR009080, tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR10890, PTHR10890, 1 hit
PfamiView protein in Pfam
PF01406, tRNA-synt_1e, 1 hit
PRINTSiPR00983, TRNASYNTHCYS
SUPFAMiSSF47323, SSF47323, 1 hit
SSF47616, SSF47616, 1 hit
TIGRFAMsiTIGR00435, cysS, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYCC_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9ER72
Secondary accession number(s): O88303
, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: September 29, 2021
This is version 154 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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