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Entry version 145 (10 Feb 2021)
Sequence version 1 (01 Mar 2001)
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Protein

Thiamine transporter 1

Gene

Slc19a2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

High-affinity transporter for the intake of thiamine.5 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-196819, Vitamin B1 (thiamin) metabolism

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Thiamine transporter 11 Publication
Short name:
ThTr-11 Publication
Alternative name(s):
Solute carrier family 19 member 2Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slc19a21 PublicationImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1928761, Slc19a2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 28CytoplasmicCuratedAdd BLAST28
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei29 – 46HelicalSequence analysisAdd BLAST18
Topological domaini47 – 71ExtracellularCuratedAdd BLAST25
Transmembranei72 – 92HelicalSequence analysisAdd BLAST21
Topological domaini93 – 105CytoplasmicCuratedAdd BLAST13
Transmembranei106 – 126HelicalSequence analysisAdd BLAST21
Topological domaini127 – 128ExtracellularCurated2
Transmembranei129 – 149HelicalSequence analysisAdd BLAST21
Topological domaini150 – 164CytoplasmicCuratedAdd BLAST15
Transmembranei165 – 185HelicalSequence analysisAdd BLAST21
Topological domaini186ExtracellularCurated1
Transmembranei187 – 207HelicalSequence analysisAdd BLAST21
Topological domaini208 – 295CytoplasmicCuratedAdd BLAST88
Transmembranei296 – 316HelicalSequence analysisAdd BLAST21
Topological domaini317 – 334ExtracellularCuratedAdd BLAST18
Transmembranei335 – 355HelicalSequence analysisAdd BLAST21
Topological domaini356 – 360CytoplasmicCurated5
Transmembranei361 – 381HelicalSequence analysisAdd BLAST21
Topological domaini382 – 386ExtracellularCurated5
Transmembranei387 – 407HelicalSequence analysisAdd BLAST21
Topological domaini408 – 423CytoplasmicCuratedAdd BLAST16
Transmembranei424 – 444HelicalSequence analysisAdd BLAST21
Topological domaini445 – 456ExtracellularCuratedAdd BLAST12
Transmembranei457 – 477HelicalSequence analysisAdd BLAST21
Topological domaini478 – 498CytoplasmicCuratedAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Males are infertile with reduced testis size and aspermia (PubMed:14567973, PubMed:14738878). Spermatogenesis fails at the pachytene spermatid stage with apoptosis of germ cells (PubMed:14567973, PubMed:14738878). When fed on a thiamine-free diet, animals develop additional phenotypes including diabetes mellitus, profound hearing loss, and defective hematopoiesis (PubMed:12393806, PubMed:14567973, PubMed:16642288). Pancreatic morphology appears to be normal although insulin secretion is significantly impaired (PubMed:12393806). Erythroid precursors in the bone marrow are almost completely absent leading to loss of reticulocytes in the peripheral blood (PubMed:14567973). The hearing loss phenotype is specifically associated with loss of cochlear inner hair cells (PubMed:16642288). These phenotypes can be reversed in many cases by re-introduction of a high thiamine diet (PubMed:12393806, PubMed:14567973, PubMed:16642288).4 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004411051 – 498Thiamine transporter 1Add BLAST498

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi63N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Modified residuei222PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9EQN9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9EQN9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9EQN9

PRoteomics IDEntifications database

More...
PRIDEi
Q9EQN9

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q9EQN9, 1 site

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9EQN9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in cochlear hair cells and duodenum (at protein level) (PubMed:11592824). Detected in pancreatic acinar cells (at protein level) (PubMed:22194418). Also expressed strongly in pancreatic islet cells (PubMed:22194418). Isoform 1: Very highly expressed in liver, and also detected at lower levels in heart, testis, kidney, brain and spleen (PubMed:11386850, PubMed:12031504). Isoform 2: Expressed at low levels in liver and spleen (PubMed:12031504).4 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

At embryonic stage 16.5 dpc detected in intestinal enterocytes, pancreatic acinar cells, and cochlear hair cells (at protein level). In newborn mice, detected in brain, kidney, liver and intestine (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000040918, Expressed in cornea and 265 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000037561

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9EQN9, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3810, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183022

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9EQN9

Identification of Orthologs from Complete Genome Data

More...
OMAi
VCYSSRP

Database of Orthologous Groups

More...
OrthoDBi
795242at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9EQN9

TreeFam database of animal gene trees

More...
TreeFami
TF313684

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002666, Folate_carrier
IPR036259, MFS_trans_sf
IPR028338, ThTr-1

The PANTHER Classification System

More...
PANTHERi
PTHR10686, PTHR10686, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01770, Folate_carrier, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF028739, Folate_carrier, 1 hit
PIRSF500794, Thiamine_transporter_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473, SSF103473, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9EQN9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDVPARVSRR AAAAAARMLL RTARVPRECW FLPTALLCAY GFFANLRPSE
60 70 80 90 100
PFLTPYLLGP DKNLTERQVY NEIYPVWTYS YLLLLFPVFL ATDYLRYKPV
110 120 130 140 150
ILLQGLSLIV TWFMLLYAQG LLAIQFLEFF YGIATATEIA YYSYIYTVVD
160 170 180 190 200
LGMYQKVTSY CRSATLVGFT VGSVLGQILV SVVGWSLFSL NVISLTCVSV
210 220 230 240 250
AFAVAWFLPM PQKSLFFHHI PSSCHGVNGL KVQNGGIVTD TPAANHLPGW
260 270 280 290 300
EDIESKIPLN LDEPPVEEPE EPKPDRLRVF RVLWNDFLMC YSSRPLLCWS
310 320 330 340 350
VWWALSTCGY FQVVNYAQGL WEKVMPSQNA DIYNGGVEAV STLLGASAVF
360 370 380 390 400
AVGYIKLSWS TWGEMTLFLC SLLIAAAVYV MDTVQSIWVC YASYVVFRII
410 420 430 440 450
YMVLITIATF QIAANLSMER YALVFGVNTF IALALQTLLT LIVVDARGLG
460 470 480 490
LCITTQFLIY ASYFAAISVV FLANGIVSII KKCRKQEDPS SSPQASTS
Length:498
Mass (Da):55,676
Last modified:March 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4B892FE1636D0F34
GO
Isoform 2 (identifier: Q9EQN9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     232-269: Missing.

Show »
Length:460
Mass (Da):51,602
Checksum:i18397F23E962BD7E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q2R3E9Q2R3_MOUSE
Thiamine transporter 1
Slc19a2
297Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti394Y → C in BAC32108 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_059029232 – 269Missing in isoform 2. CuratedAdd BLAST38

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF224341 Genomic DNA Translation: AAL11497.1
AF179403 mRNA Translation: AAG43424.1
AF360396 mRNA Translation: AAL30451.1
AF216204 mRNA Translation: AAK33067.1
AF326916 mRNA Translation: AAL85635.1
AF418986 mRNA Translation: AAM47550.1
AK044825 mRNA Translation: BAC32108.1
AC105161 Genomic DNA No translation available.
CH466520 Genomic DNA Translation: EDL39259.1
BC034659 mRNA Translation: AAH34659.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS15433.1 [Q9EQN9-1]
CCDS69968.1 [Q9EQN9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001263384.1, NM_001276455.1 [Q9EQN9-2]
NP_473428.1, NM_054087.3 [Q9EQN9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000044021; ENSMUSP00000037561; ENSMUSG00000040918 [Q9EQN9-1]
ENSMUST00000159230; ENSMUSP00000123870; ENSMUSG00000040918 [Q9EQN9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
116914

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:116914

UCSC genome browser

More...
UCSCi
uc007did.2, mouse [Q9EQN9-1]
uc007die.2, mouse

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF224341 Genomic DNA Translation: AAL11497.1
AF179403 mRNA Translation: AAG43424.1
AF360396 mRNA Translation: AAL30451.1
AF216204 mRNA Translation: AAK33067.1
AF326916 mRNA Translation: AAL85635.1
AF418986 mRNA Translation: AAM47550.1
AK044825 mRNA Translation: BAC32108.1
AC105161 Genomic DNA No translation available.
CH466520 Genomic DNA Translation: EDL39259.1
BC034659 mRNA Translation: AAH34659.1
CCDSiCCDS15433.1 [Q9EQN9-1]
CCDS69968.1 [Q9EQN9-2]
RefSeqiNP_001263384.1, NM_001276455.1 [Q9EQN9-2]
NP_473428.1, NM_054087.3 [Q9EQN9-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037561

PTM databases

GlyGeniQ9EQN9, 1 site
PhosphoSitePlusiQ9EQN9

Proteomic databases

EPDiQ9EQN9
MaxQBiQ9EQN9
PaxDbiQ9EQN9
PRIDEiQ9EQN9

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1655, 90 antibodies

Genome annotation databases

EnsembliENSMUST00000044021; ENSMUSP00000037561; ENSMUSG00000040918 [Q9EQN9-1]
ENSMUST00000159230; ENSMUSP00000123870; ENSMUSG00000040918 [Q9EQN9-2]
GeneIDi116914
KEGGimmu:116914
UCSCiuc007did.2, mouse [Q9EQN9-1]
uc007die.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10560
MGIiMGI:1928761, Slc19a2

Phylogenomic databases

eggNOGiKOG3810, Eukaryota
GeneTreeiENSGT00950000183022
InParanoidiQ9EQN9
OMAiVCYSSRP
OrthoDBi795242at2759
PhylomeDBiQ9EQN9
TreeFamiTF313684

Enzyme and pathway databases

ReactomeiR-MMU-196819, Vitamin B1 (thiamin) metabolism

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
116914, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Slc19a2, mouse

Protein Ontology

More...
PROi
PR:Q9EQN9
RNActiQ9EQN9, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000040918, Expressed in cornea and 265 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR002666, Folate_carrier
IPR036259, MFS_trans_sf
IPR028338, ThTr-1
PANTHERiPTHR10686, PTHR10686, 1 hit
PfamiView protein in Pfam
PF01770, Folate_carrier, 1 hit
PIRSFiPIRSF028739, Folate_carrier, 1 hit
PIRSF500794, Thiamine_transporter_1, 1 hit
SUPFAMiSSF103473, SSF103473, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS19A2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9EQN9
Secondary accession number(s): Q8BRH5, Q8R4Y1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2017
Last sequence update: March 1, 2001
Last modified: February 10, 2021
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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