UniProtKB - Q9EQB5 (Q9EQB5_MOUSE)
Protein
Olfactory receptor
Gene
Olfr945
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- G protein-coupled receptor activity Source: UniProtKB-KW
- odorant binding Source: GO_Central
- olfactory receptor activity Source: MGI
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: MGI
- sensory perception of smell Source: MGI
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotationARBA annotation, Receptor, Transducer |
Biological process | OlfactionUniRule annotationARBA annotation, Sensory transduction |
Enzyme and pathway databases
Reactomei | R-MMU-381753, Olfactory Signaling Pathway |
Names & Taxonomyi
Protein namesi | Recommended name: Olfactory receptorUniRule annotation |
Gene namesi | Name:Olfr945Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:3030779, Olfr945 |
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotationARBA annotation; Multi-pass membrane protein UniRule annotationARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: MGI
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 30 – 54 | HelicalUniRule annotationAdd BLAST | 25 | |
Transmembranei | 61 – 82 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 94 – 119 | HelicalUniRule annotationAdd BLAST | 26 | |
Transmembranei | 150 – 169 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 203 – 229 | HelicalUniRule annotationAdd BLAST | 27 | |
Transmembranei | 241 – 264 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 276 – 295 | HelicalUniRule annotationAdd BLAST | 20 |
Keywords - Cellular componenti
Cell membraneUniRule annotationARBA annotation, MembraneExpressioni
Gene expression databases
Bgeei | ENSMUSG00000063380, Expressed in forelimb bud and 2 other tissues |
ExpressionAtlasi | Q9EQB5, differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 44 – 293 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 250 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | ENOG502SJS1, Eukaryota |
GeneTreei | ENSGT00980000198557 |
HOGENOMi | CLU_012526_1_0_1 |
OrthoDBi | 1075792at2759 |
TreeFami | TF336827 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR000725, Olfact_rcpt |
Pfami | View protein in Pfam PF13853, 7tm_4, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00245, OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q9EQB5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEDMTSGNNC TVSEFFLAGL SEEPELQLPL FLLFTGIYLI TVVGNLGMIT
60 70 80 90 100
LIGISSHLHT AMYFFLSSLS FIDFCQSTVV TPKMLVSFLT EKNIISYLGC
110 120 130 140 150
MAQLYFFIIF GAAECYTLAA MAYDRYVAIC NPLLYTVVMS YQVYSSLISG
160 170 180 190 200
VYIYAVFCAS VHTGVLTRIQ FCKLDVINHY FCDILPLLKL ACSNTYIDEM
210 220 230 240 250
LILFFGTLNI FAPTLIIITS YIFIIASIFH IRSREGRSKA FSTCSSHISA
260 270 280 290 300
VAIFYGSAAF MYLQPSRVNS MDQGKVSSVF YTTVVPMLNP LIYSLRNKDV
310
TVALKKILER KNFMWSEVT
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ7TRB3 | Q7TRB3_MOUSE | Olfactory receptor | Olfr945 | 316 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC073945 Genomic DNA No translation available. AF282274 Genomic DNA Translation: AAG39859.1 BC128004 mRNA Translation: AAI28005.1 AY073591 Genomic DNA Translation: AAL61254.1 |
RefSeqi | NP_666717.1, NM_146506.1 |
Genome annotation databases
Ensembli | ENSMUST00000076903; ENSMUSP00000076169; ENSMUSG00000063380 |
GeneIDi | 258499 |
KEGGi | mmu:258499 |
UCSCi | uc009oxu.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC073945 Genomic DNA No translation available. AF282274 Genomic DNA Translation: AAG39859.1 BC128004 mRNA Translation: AAI28005.1 AY073591 Genomic DNA Translation: AAL61254.1 |
RefSeqi | NP_666717.1, NM_146506.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000076169 |
Protein family/group databases
GPCRDBi | Search... |
Genome annotation databases
Ensembli | ENSMUST00000076903; ENSMUSP00000076169; ENSMUSG00000063380 |
GeneIDi | 258499 |
KEGGi | mmu:258499 |
UCSCi | uc009oxu.1, mouse |
Organism-specific databases
CTDi | 258499 |
MGIi | MGI:3030779, Olfr945 |
Phylogenomic databases
eggNOGi | ENOG502SJS1, Eukaryota |
GeneTreei | ENSGT00980000198557 |
HOGENOMi | CLU_012526_1_0_1 |
OrthoDBi | 1075792at2759 |
TreeFami | TF336827 |
Enzyme and pathway databases
Reactomei | R-MMU-381753, Olfactory Signaling Pathway |
Miscellaneous databases
BioGRID-ORCSi | 258499, 0 hits in 11 CRISPR screens |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000063380, Expressed in forelimb bud and 2 other tissues |
ExpressionAtlasi | Q9EQB5, differential |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR000725, Olfact_rcpt |
Pfami | View protein in Pfam PF13853, 7tm_4, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00245, OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9EQB5_MOUSE | |
Accessioni | Q9EQB5Primary (citable) accession number: Q9EQB5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2001 |
Last sequence update: | March 1, 2001 | |
Last modified: | February 10, 2021 | |
This is version 147 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |