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Entry version 117 (16 Oct 2019)
Sequence version 2 (15 Nov 2002)
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Protein

StAR-related lipid transfer protein 5

Gene

Stard5

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processLipid transport, Transport
LigandLipid-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-159418 Recycling of bile acids and salts

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
StAR-related lipid transfer protein 5
Alternative name(s):
START domain-containing protein 5
Short name:
StARD5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Stard5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2156765 Stard5

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002206701 – 213StAR-related lipid transfer protein 5Add BLAST213

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9EPQ7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9EPQ7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9EPQ7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9EPQ7

PeptideAtlas

More...
PeptideAtlasi
Q9EPQ7

PRoteomics IDEntifications database

More...
PRIDEi
Q9EPQ7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9EPQ7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9EPQ7

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q9EPQ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in most tissues, with highest levels in liver and in kidney.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000046027 Expressed in 212 organ(s), highest expression level in adult mammalian kidney

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9EPQ7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9EPQ7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9EPQ7, 3 interactors

Molecular INTeraction database

More...
MINTi
Q9EPQ7

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000074872

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9EPQ7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 213STARTPROSITE-ProRule annotationAdd BLAST213

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3845 Eukaryota
ENOG41100B5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159159

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000137345

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9EPQ7

Identification of Orthologs from Complete Genome Data

More...
OMAi
WRPSTEF

Database of Orthologous Groups

More...
OrthoDBi
1469639at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9EPQ7

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.530.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000799 StAR-like
IPR029868 StARD5
IPR023393 START-like_dom_sf
IPR002913 START_lipid-bd_dom

The PANTHER Classification System

More...
PANTHERi
PTHR46374:SF3 PTHR46374:SF3, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01852 START, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00978 STARPROTEIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00234 START, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50848 START, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9EPQ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPSWATQES EAVAEKVLRY RRDASGWKKC REGNGVSISW RPSEEFPGNL
60 70 80 90 100
YRGEGILCGT PEEVWDCIKP VASGLREKWD DNVSSFEIVQ SITDMLCVSR
110 120 130 140 150
TSTPSAAMKL ISPRDFVDLV LVKKYEDGTI SSNATHVEHP LCPPKPGFVR
160 170 180 190 200
GFNHPCGCFC EPLPGDPNKT NLVTFFQTDL SGYLPQSVVD SFFPRSMAEF
210
YPNLQKAVRK FHH
Length:213
Mass (Da):23,922
Last modified:November 15, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB689F28F9D377209
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YU00D3YU00_MOUSE
StAR-related lipid transfer (START)...
Stard5 mCG_8260
206Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY007808 mRNA Translation: AAG41056.1
AY007809 mRNA Translation: AAG41057.1
AF480302 mRNA Translation: AAL89652.1
AK009980 mRNA Translation: BAB26624.2
AK080060 mRNA Translation: BAC37819.1
AK085852 mRNA Translation: BAC39551.1
AK142503 mRNA Translation: BAE25090.1
AK158178 mRNA Translation: BAE34395.1
BC058226 mRNA Translation: AAH58226.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS21411.1

NCBI Reference Sequences

More...
RefSeqi
NP_075866.2, NM_023377.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000075418; ENSMUSP00000074872; ENSMUSG00000046027

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
170460

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:170460

UCSC genome browser

More...
UCSCi
uc009idq.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY007808 mRNA Translation: AAG41056.1
AY007809 mRNA Translation: AAG41057.1
AF480302 mRNA Translation: AAL89652.1
AK009980 mRNA Translation: BAB26624.2
AK080060 mRNA Translation: BAC37819.1
AK085852 mRNA Translation: BAC39551.1
AK142503 mRNA Translation: BAE25090.1
AK158178 mRNA Translation: BAE34395.1
BC058226 mRNA Translation: AAH58226.1
CCDSiCCDS21411.1
RefSeqiNP_075866.2, NM_023377.4

3D structure databases

SMRiQ9EPQ7
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9EPQ7, 3 interactors
MINTiQ9EPQ7
STRINGi10090.ENSMUSP00000074872

PTM databases

iPTMnetiQ9EPQ7
PhosphoSitePlusiQ9EPQ7
SwissPalmiQ9EPQ7

Proteomic databases

EPDiQ9EPQ7
jPOSTiQ9EPQ7
MaxQBiQ9EPQ7
PaxDbiQ9EPQ7
PeptideAtlasiQ9EPQ7
PRIDEiQ9EPQ7

Genome annotation databases

EnsembliENSMUST00000075418; ENSMUSP00000074872; ENSMUSG00000046027
GeneIDi170460
KEGGimmu:170460
UCSCiuc009idq.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80765
MGIiMGI:2156765 Stard5

Phylogenomic databases

eggNOGiKOG3845 Eukaryota
ENOG41100B5 LUCA
GeneTreeiENSGT00940000159159
HOGENOMiHOG000137345
InParanoidiQ9EPQ7
OMAiWRPSTEF
OrthoDBi1469639at2759
PhylomeDBiQ9EPQ7

Enzyme and pathway databases

ReactomeiR-MMU-159418 Recycling of bile acids and salts

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Stard5 mouse

Protein Ontology

More...
PROi
PR:Q9EPQ7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000046027 Expressed in 212 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiQ9EPQ7 baseline and differential
GenevisibleiQ9EPQ7 MM

Family and domain databases

Gene3Di3.30.530.20, 1 hit
InterProiView protein in InterPro
IPR000799 StAR-like
IPR029868 StARD5
IPR023393 START-like_dom_sf
IPR002913 START_lipid-bd_dom
PANTHERiPTHR46374:SF3 PTHR46374:SF3, 1 hit
PfamiView protein in Pfam
PF01852 START, 1 hit
PRINTSiPR00978 STARPROTEIN
SMARTiView protein in SMART
SM00234 START, 1 hit
PROSITEiView protein in PROSITE
PS50848 START, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSTAR5_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9EPQ7
Secondary accession number(s): Q9CQY0, Q9EPQ6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: November 15, 2002
Last modified: October 16, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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