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Protein

Retinoid-binding protein 7

Gene

Rbp7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Intracellular transport of retinol.By similarity

GO - Molecular functioni

  • retinal binding Source: UniProtKB-KW
  • retinoid binding Source: MGI
  • retinol binding Source: UniProtKB-KW

Keywordsi

Biological processTransport
LigandRetinol-binding, Vitamin A

Names & Taxonomyi

Protein namesi
Recommended name:
Retinoid-binding protein 7
Alternative name(s):
Cellular retinoic acid-binding protein 4
Short name:
CRABP4
Short name:
CRBP4
Cellular retinoic acid-binding protein IV
Short name:
CRABP-IV
Gene namesi
Name:Rbp7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1890409 Rbp7

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000674041 – 134Retinoid-binding protein 7Add BLAST134

Proteomic databases

MaxQBiQ9EPC5
PaxDbiQ9EPC5
PRIDEiQ9EPC5

Expressioni

Tissue specificityi

Highly expressed in white adipose tissue and mammary gland.

Gene expression databases

BgeeiENSMUSG00000028996 Expressed in 110 organ(s), highest expression level in heart left ventricle
CleanExiMM_RBP7
ExpressionAtlasiQ9EPC5 baseline and differential
GenevisibleiQ9EPC5 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030848

Structurei

3D structure databases

ProteinModelPortaliQ9EPC5
SMRiQ9EPC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4015 Eukaryota
ENOG4111US8 LUCA
GeneTreeiENSGT00760000118898
HOGENOMiHOG000004831
HOVERGENiHBG005633
InParanoidiQ9EPC5
OMAiVTKGMDN
OrthoDBiEOG091G0QSV
PhylomeDBiQ9EPC5
TreeFamiTF316894

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9EPC5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPADLSGTWN LLSSDNFEGY MLALGIDFAT RKIAKLLKPQ KVIEQNGDSF
60 70 80 90 100
TIQTCSSLRN YLVKFKVGEE FEEDNKGLDN RKCTSLVTWE NDKLTCVQRG
110 120 130
EKKNRGWSHW IEGDQLHLEM FCEGQVCKQT FQRA
Length:134
Mass (Da):15,428
Last modified:March 1, 2001 - v1
Checksum:i04D1A591AD7263E6
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6R1Y3F6R1Y3_MOUSE
Retinoid-binding protein 7
Rbp7
68Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF260927 Genomic DNA Translation: AAG38491.1
AF260923 mRNA Translation: AAG17284.1
BC028432 mRNA Translation: AAH28432.1
AK003307 mRNA Translation: BAB22705.1
CCDSiCCDS18959.1
RefSeqiNP_071303.1, NM_022020.2
UniGeneiMm.46023

Genome annotation databases

EnsembliENSMUST00000030848; ENSMUSP00000030848; ENSMUSG00000028996
GeneIDi63954
KEGGimmu:63954
UCSCiuc008vwh.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF260927 Genomic DNA Translation: AAG38491.1
AF260923 mRNA Translation: AAG17284.1
BC028432 mRNA Translation: AAH28432.1
AK003307 mRNA Translation: BAB22705.1
CCDSiCCDS18959.1
RefSeqiNP_071303.1, NM_022020.2
UniGeneiMm.46023

3D structure databases

ProteinModelPortaliQ9EPC5
SMRiQ9EPC5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030848

Proteomic databases

MaxQBiQ9EPC5
PaxDbiQ9EPC5
PRIDEiQ9EPC5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030848; ENSMUSP00000030848; ENSMUSG00000028996
GeneIDi63954
KEGGimmu:63954
UCSCiuc008vwh.1 mouse

Organism-specific databases

CTDi116362
MGIiMGI:1890409 Rbp7

Phylogenomic databases

eggNOGiKOG4015 Eukaryota
ENOG4111US8 LUCA
GeneTreeiENSGT00760000118898
HOGENOMiHOG000004831
HOVERGENiHBG005633
InParanoidiQ9EPC5
OMAiVTKGMDN
OrthoDBiEOG091G0QSV
PhylomeDBiQ9EPC5
TreeFamiTF316894

Miscellaneous databases

PROiPR:Q9EPC5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000028996 Expressed in 110 organ(s), highest expression level in heart left ventricle
CleanExiMM_RBP7
ExpressionAtlasiQ9EPC5 baseline and differential
GenevisibleiQ9EPC5 MM

Family and domain databases

Gene3Di2.40.128.20, 1 hit
InterProiView protein in InterPro
IPR012674 Calycin
IPR000463 Fatty_acid-bd
IPR031259 ILBP
IPR000566 Lipocln_cytosolic_FA-bd_dom
PANTHERiPTHR11955 PTHR11955, 1 hit
PfamiView protein in Pfam
PF00061 Lipocalin, 1 hit
PRINTSiPR00178 FATTYACIDBP
SUPFAMiSSF50814 SSF50814, 1 hit
PROSITEiView protein in PROSITE
PS00214 FABP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRET7_MOUSE
AccessioniPrimary (citable) accession number: Q9EPC5
Secondary accession number(s): Q9CTK0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: March 1, 2001
Last modified: November 7, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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