Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Envelope glycoprotein D

Gene

MDV094

Organism
Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Envelope glycoprotein that binds to host cell entry receptors. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processHost-virus interaction, Viral attachment to host cell, Viral attachment to host entry receptor, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Envelope glycoprotein D
Short name:
gD
Gene namesi
Name:MDV094
OrganismiGallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's disease herpesvirus type 1)
Taxonomic identifieri10389 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeMardivirus
Virus hostiGallus gallus (Chicken) [TaxID: 9031]
Proteomesi
  • UP000008072 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini35 – 357Virion surfaceSequence analysisAdd BLAST323
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21
Topological domaini379 – 403IntravirionSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Viral envelope protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 34Sequence analysisAdd BLAST34
ChainiPRO_000040659635 – 403Envelope glycoprotein DAdd BLAST369

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi87N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Disulfide bondi88 ↔ 209By similarity
Disulfide bondi127 ↔ 222By similarity
Glycosylationi138N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Disulfide bondi139 ↔ 148By similarity
Glycosylationi230N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi306N-linked (GlcNAc...) asparagine; by hostSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiQ9E6L6

Structurei

3D structure databases

ProteinModelPortaliQ9E6L6
SMRiQ9E6L6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000AQ

Family and domain databases

InterProiView protein in InterPro
IPR002896 Herpes_glycop_dom
IPR036179 Ig-like_dom_sf
PfamiView protein in Pfam
PF01537 Herpes_glycop_D, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9E6L6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNRYRYESIF FRYISSTRMI LIICLLLGIG DMSAMGLKKD NSPIIPTLHP
60 70 80 90 100
KGNENLRATL NEYKIPSPLF DTLDNSYETK HVIYTDNCSF AVLNPFGDPK
110 120 130 140 150
YTLLSLLLMG RRKYDALVAW FVLGRACGRP IYLREYANCS TNEPFGTCKL
160 170 180 190 200
KSLGWWDRRY AMTSYIDRDE LKLIIAAPSR ELSGLYTRLI IINGEPISSD
210 220 230 240 250
ILLTVKETCS FSRRGIKDNK LCKPFSFFVN GTTRLLDMVG TGTPRAHEEN
260 270 280 290 300
VKQWLERIGG KHLPIVVETS MQQVSNLPRS FRDSYFKSPD DDKYDDVKMT
310 320 330 340 350
SATTNNITTS VDGYTGLTNR PEDFEKAPYI TKRPIISVEE ASSQSPKIST
360 370 380 390 400
EKKSRTQIII SLVVLCVMFC FIVIGSGIWI LRKHRKTVMY DRRRPSRRAY

SRL
Length:403
Mass (Da):46,199
Last modified:March 1, 2001 - v1
Checksum:iA2BC7235EAA5E938
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF243438 Genomic DNA Translation: AAG14268.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF243438 Genomic DNA Translation: AAG14268.1

3D structure databases

ProteinModelPortaliQ9E6L6
SMRiQ9E6L6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ9E6L6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

OrthoDBiVOG090000AQ

Family and domain databases

InterProiView protein in InterPro
IPR002896 Herpes_glycop_dom
IPR036179 Ig-like_dom_sf
PfamiView protein in Pfam
PF01537 Herpes_glycop_D, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGD_GAHVM
AccessioniPrimary (citable) accession number: Q9E6L6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: March 1, 2001
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again