UniProtKB - Q9DEH7 (Q9DEH7_DANRE)
Protein
Submitted name:
Kheper
Gene
zeb1b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- gastrulation Source: ZFIN
- regulation of cell-cell adhesion involved in gastrulation Source: ZFIN
- regulation of cell motility Source: ZFIN
- regulation of gastrulation Source: ZFIN
Keywordsi
Molecular function | DNA-bindingUniRule annotationImported |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: KheperImportedSubmitted name: Zinc finger homeobox 1Imported |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Organism-specific databases
ZFINi | ZDB-GENE-010621-1, zeb1b |
Subcellular locationi
Keywords - Cellular componenti
NucleusUniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 137 – 165 | C2H2-typeInterPro annotationAdd BLAST | 29 | |
Domaini | 167 – 194 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 209 – 236 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 237 – 271 | C2H2-typeInterPro annotationAdd BLAST | 35 | |
Domaini | 831 – 858 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 859 – 886 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 887 – 915 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 87 | DisorderedSequence analysisAdd BLAST | 87 | |
Regioni | 102 – 132 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 272 – 296 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 583 – 624 | DisorderedSequence analysisAdd BLAST | 42 | |
Regioni | 799 – 823 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 919 – 1078 | DisorderedSequence analysisAdd BLAST | 160 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 29 – 47 | PolyampholyteSequence analysisAdd BLAST | 19 | |
Compositional biasi | 65 – 87 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 279 – 296 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 935 – 952 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 960 – 975 | AcidicSequence analysisAdd BLAST | 16 | |
Compositional biasi | 984 – 1013 | AcidicSequence analysisAdd BLAST | 30 | |
Compositional biasi | 1025 – 1040 | AcidicSequence analysisAdd BLAST | 16 | |
Compositional biasi | 1041 – 1062 | PolyampholyteSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.ARBA annotation
Keywords - Domaini
HomeoboxUniRule annotationImported, Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
OrthoDBi | 890458at2759 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR008598, Di19_Zn_binding_dom IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF00096, zf-C2H2, 3 hits PF05605, zf-Di19, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF57667, SSF57667, 4 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 5 hits PS50157, ZINC_FINGER_C2H2_2, 7 hits |
i Sequence
Sequence statusi: Complete.
Q9DEH7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADGPRCKRR KQANPRRTNV SNYSHVLEGQ SDSDDEDKLH IVEEEGSLLD
60 70 80 90 100
GADCDSVAPD DDPNGTADPD GRWDDVKEEC VSDEDERSRD ALVEEMLQQG
110 120 130 140 150
DTAVIFPEAP DDEPRQGTPE TSGHDENGTP DSFSQLLTCP YCSRGYKRYT
160 170 180 190 200
SLKEHIKYRH EKSEDNFSCS LCSYTFAYRT QLDRHMTAHK AGREQRHVTQ
210 220 230 240 250
SGGGGNRKFK CTECGKAFKY KHHLKEHLRI HSGEKPYECS NCKKRFSHSG
260 270 280 290 300
SYSSHISSKK CIGLISVNGR PRPSPATGAA KTPQCSSPYL PTSSPTARVQ
310 320 330 340 350
VRDKLDNSKP LQEQLPLTQI KSEPLDYEYK PVVVAPSARG VNGMFQGGAA
360 370 380 390 400
APLQGAVQAV VLPTVGLVSP ISINLGDLQN VLKVAVDGNV IRQVLESTQA
410 420 430 440 450
KGQQAGTGIV GAGGIAQATQ QVIQAISLPI LDQDGNAKIF INYSLDPSQA
460 470 480 490 500
QAVLQSPKKE PLGSNTEVCK GQKLPEDLTV KTNRDKTTLT VDEKSMLHND
510 520 530 540 550
ILLKHCGKDE HRINGKNLEE KMDLEGLCPG QPPLKNLLSL LKAYFALNNE
560 570 580 590 600
PTKEELAKIS ESVSLPAEVV KKWFEKMQLG QISMDPSSPQ HEEEQTTPVD
610 620 630 640 650
LDGTKGASPK PDLDEQMNSE KQEERECCSP AEGIAASVNG IESVPASPSP
660 670 680 690 700
LNLSADGPVP ARTLEEGEGP LDLSLPKSAT TASVASGHAN TVYSAQEEPL
710 720 730 740 750
NLTCTKKELL SNASTNAAIY ASQPSANPIN IMTTQLPTLV AITDQGQAQC
760 770 780 790 800
LRALTTTKQT ILIPQLTYSY TTTSSSPAGT DTPQKNILHV NGIKEEKQEM
810 820 830 840 850
GSEATSILEE QTDSDSGPTK KKMKRTESGL YACDLCDKIF QKSSSLLRHK
860 870 880 890 900
YEHTGKRPHE CGICSKAFKH KHHLIEHLRL HSGEKPYQCD KCGKRFSHSG
910 920 930 940 950
SYSQHMNHRY SYCKKEAQGQ GLGQGVEEED NPGEEQPQTG STATSPPSHL
960 970 980 990 1000
DSDERGSSTR DDESEEEDEM GSGSLVDEDE IQVVKIGEEG DEDDQGADED
1010 1020 1030 1040 1050
QERMEEDGDE EGEGETLKVV VMQDECEEDE NEEDEQTSED AMDTSDHTEE
1060 1070
MTERKTPGDN KNIGEHEGNT AAMNGDVK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC162144 mRNA Translation: AAI62144.1 AB016799 mRNA Translation: BAB18865.1 |
RefSeqi | NP_571784.1, NM_131709.1 |
Genome annotation databases
GeneIDi | 114425 |
KEGGi | dre:114425 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC162144 mRNA Translation: AAI62144.1 AB016799 mRNA Translation: BAB18865.1 |
RefSeqi | NP_571784.1, NM_131709.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 114425 |
KEGGi | dre:114425 |
Organism-specific databases
CTDi | 114425 |
ZFINi | ZDB-GENE-010621-1, zeb1b |
Phylogenomic databases
OrthoDBi | 890458at2759 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR008598, Di19_Zn_binding_dom IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00046, Homeodomain, 1 hit PF00096, zf-C2H2, 3 hits PF05605, zf-Di19, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit SM00355, ZnF_C2H2, 7 hits |
SUPFAMi | SSF46689, SSF46689, 1 hit SSF57667, SSF57667, 4 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 5 hits PS50157, ZINC_FINGER_C2H2_2, 7 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q9DEH7_DANRE | |
Accessioni | Q9DEH7Primary (citable) accession number: Q9DEH7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2001 |
Last sequence update: | March 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |