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UniProtKB - Q9DE14 (ATR_XENLA)

Entry version 102 (10 Feb 2021)
Sequence version 2 (07 Mar 2006)
Previous versions | rss
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Protein

Serine/threonine-protein kinase atr

Gene

atr

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates 'Ser-139' of histone variant H2AX at sites of DNA damage, thereby regulating DNA damage response mechanism.3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mn2+By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Kinase activity is activated by topbp1.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Kinase, Serine/threonine-protein kinase, Transferase
Biological processDNA damage, DNA repair
LigandATP-binding, Manganese, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Serine/threonine-protein kinase atr (EC:2.7.11.1)
Short name:
Xatr
Alternative name(s):
Ataxia telangiectasia and Rad3-related protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:atr
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus laevis (African clawed frog)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8355 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...Xenbasei		XB-GENE-1012725, atr.L

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002256281 – 2654Serine/threonine-protein kinase atrAdd BLAST2654

Keywords - PTMi

Phosphoprotein

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9DE14

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a heterodimer with atrip.

Interacts with topbp1 in the presence of atrip.

1 Publication

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		99532, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q9DE14, 2 interactors

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati814 – 850HEAT 1Add BLAST37
Repeati1344 – 1380HEAT 2Add BLAST37
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1654 – 2196FATPROSITE-ProRule annotationAdd BLAST543
Domaini2331 – 2577PI3K/PI4KPROSITE-ProRule annotationAdd BLAST247
Domaini2622 – 2654FATCPROSITE-ProRule annotationAdd BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PI3/PI4-kinase family. ATM subfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...OMAi		WMLLPHF

Database of Orthologous Groups

More...OrthoDBi		80538at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1070.11, 1 hit
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR003152, FATC_dom
IPR011009, Kinase-like_dom_sf
IPR000403, PI3/4_kinase_cat_dom
IPR036940, PI3/4_kinase_cat_sf
IPR018936, PI3/4_kinase_CS
IPR003151, PIK-rel_kinase_FAT
IPR014009, PIK_FAT
IPR011990, TPR-like_helical_dom_sf
IPR012993, UME

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02259, FAT, 1 hit
PF02260, FATC, 1 hit
PF00454, PI3_PI4_kinase, 1 hit
PF08064, UME, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01343, FATC, 1 hit
SM00146, PI3Kc, 1 hit
SM00802, UME, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit
SSF48452, SSF48452, 1 hit
SSF56112, SSF56112, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51189, FAT, 1 hit
PS51190, FATC, 1 hit
PS00916, PI3_4_KINASE_2, 1 hit
PS50290, PI3_4_KINASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9DE14-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATDPGLEMA SMIPALRELA SAGAEEYNTT VQKPRQILCQ FIDRILTDVD 
        60         70         80         90        100
VVAVELSKNT DSQPSSVMLL DFIQHIMKST PLMFLSANNG DQSAETNQNC 
       110        120        130        140        150
VAFSNWIISR LLRIGATPSC KALHRKIAEV IRSLLFLFKN KSSFLFGVFT 
       160        170        180        190        200
KDLLHLFEDL IYIHEQNMEK SVVWPVTISR FLSNASENQT YLRCTQFQLL 
       210        220        230        240        250
NMQNIEPLES TLLMVLMDNE HDISPVFFQR QNLLLWGIGC SLLDYGSTPL 
       260        270        280        290        300
KIQALHFLRQ LIKLGGPPEQ GAYFFFIVFF GILTCIKDMD LEEVSLYEMP 
       310        320        330        340        350
LLKLVKVLFP FESKSYLNIE PVYLNMLLEK LAALFDGGIL SNIQSAPLKE 
       360        370        380        390        400
ALCYMVHYFL SIVPPGYESA KEVREAHVRC ICRAFVDVLG LQSKQEYLVC 
       410        420        430        440        450
PLHEALRIEN LVFMQQQRMQ PLSTDSEGGG SSSSDEVQEK RPRLSLTAKP 
       460        470        480        490        500
LRRNTPSVPA PVDMKTKSIL WKAVSAKFSS ILCKLEGDEV TDEEMVSLLE 
       510        520        530        540        550
GLNTTVRVAA LNTVHIFTND STDTDQLVSD LSNTSGIQSV EIVPHVFWLS 
       560        570        580        590        600
PEDILKILKI CRKVLDSAHQ RANINDILMK IIKIFDAILY IHAGNRLNDQ 
       610        620        630        640        650
TLKDLCSMIS LPWLQNHSNH ASFKVASFDP TLMTISERIG QHYSPEIQSQ 
       660        670        680        690        700
LVFLLCLFPK MLCPEWRLAV YQWALDSPHE IVRARCIKGF PVLLCNVSQQ 
       710        720        730        740        750
GYGPIPKILI DCLNDASELV KKELANSVGM FASGLACGFE LQYSPTAPTA 
       760        770        780        790        800
AESEFLCSSL TVTALPSSKL SRMTASALKP FLALLNRNMP SSVKMAFIEN 
       810        820        830        840        850
MPMLFAHLSL EKDDLDSRTV IESLLNLMED PDKDVRTAFS GNIKHLLACA 
       860        870        880        890        900
DCEDGYLKEI VVSRMKKAYT DAKMSRDNEM KDTLILTTGD IGRAAKGELV 
       910        920        930        940        950
PFALLHLLHC LLSKSPCVAG ASYTEIRSLA AAKSTSLHIF FSQYKKPICQ 
       960        970        980        990       1000
FLIESLHSSQ AALLTNTPGR SSEMQKQEAT HHREAALDIL SEIANVFDFP 
      1010       1020       1030       1040       1050
DLNRFLTRTL QLLLPYLAAK ASPTASTLIR TIAKQLNVNR REILINNFKY 
      1060       1070       1080       1090       1100
IFSHLVCSCT KDELEKSLHY LKNETEIELG SLLRQDYQGL HNELLLRLGE 
      1110       1120       1130       1140       1150
HYQQVFSGLS ILATYASNDD PYQGPRNFAK PEIMADYLQP KLLGILAFFN 
      1160       1170       1180       1190       1200
MHLLSSSIGI EDKKMALNSL VSLMKLMGPK HISSVRVKMM TTLRTGLRYK 
      1210       1220       1230       1240       1250
EEFPGLCCSA WDLFVRCLDQ AYLGPLLSHV IVALLPLLHI QPKETVAVFR 
      1260       1270       1280       1290       1300
YLIVENRDAV QDFLHEIYFL PDHPELKEIQ KVLQEYRKET TKSTDLQTAM 
      1310       1320       1330       1340       1350
QLSIRAIQHE NVDVRMHALT SLKETLYKNQ AKLLQYSTDS ETVEPVISQL 
      1360       1370       1380       1390       1400
VTVLLIGCQD ANPQARLFCG ECLGQLGAID PGRLDFSPSE TQGKGFTFVS 
      1410       1420       1430       1440       1450
GVEDSDFAYE LLTEQTRAFL AYADNVRAQD SAAYAIQELL SIFECKEGRT 
      1460       1470       1480       1490       1500
DCPGRRLWRR FPEHVQEILE PHLNTRYKSS RKAVNWSRVK KPIYLSKLGN 
      1510       1520       1530       1540       1550
NFADWSATWA GYLITKVRHE LARRVFSCCS IMMKHDFKVT IYLLPHILVY 
      1560       1570       1580       1590       1600
VLLGCNKEDQ QEVYAEIMAV LKHEDPLMRR LQDSASDLSQ LSTQTVFSML 
      1610       1620       1630       1640       1650
DHLTQWAREK FQALNAEKTN PKPGTRGEPK AVSNEDYGEY QNVTRFLDLI 
      1660       1670       1680       1690       1700
PQDTLAVASF RSKAYTRALM HFESFIMEKK QEIQEHLGFL QKLYAAMHEP 
      1710       1720       1730       1740       1750
DGVAGVSAIR KKEASLKEQI LEHESIGLLR DATACYDRAI QLKPEEIIHY 
      1760       1770       1780       1790       1800
HGVVKSMLGL GQLSTVITQV NGILNSRSEW TAELNTYRVE AAWKLSQWDL 
      1810       1820       1830       1840       1850
VEEYLSADRK STTWSIRLGQ LLLSAKKGER DMFYETLKVV RAEQIVPLSA 
      1860       1870       1880       1890       1900
ASFERGSYQR GYEYIVRLHM LCELEHSVKM FLQKPSVEPA VDSLNLPARL 
      1910       1920       1930       1940       1950
EMTQNSYRAR EPILAVRRAL QTINKRPNHA DMIGECWLQS ARVARKAGHH 
      1960       1970       1980       1990       2000
QTAYNALLNA GESRLSELNV ERAKWLWSKG DVHQALIVLQ KGAELFLSST 
      2010       2020       2030       2040       2050
SAPPEQQLIH GRAMLLVGRL MEETANFESN AVMKKYKDVT ALLPEWEDGH 
      2060       2070       2080       2090       2100
FYLAKYYDKL MPMVTDNKME KQGDLIRYIV LHFGRSLQFG NQYIYQSMPR 
      2110       2120       2130       2140       2150
MLSLWLDFGA KVYEWEKAGR ADRLQMKNEL MKINKVISDH KNQLAPYQFL 
      2160       2170       2180       2190       2200
TAFSQLISRI CHSHDEVFAV LMEIVAKVFV AYPQQAMWMM TAVSKSSYPM 
      2210       2220       2230       2240       2250
RVNRCKEILE KAIHMKPSLG KFIGDATRLT DKLLELCNKP VDGNTSTLSM 
      2260       2270       2280       2290       2300
NIHFKMLKKL VEETTFSEIL IPLQSVMIPT LPSTAGKRDH ADHDPFPGHW 
      2310       2320       2330       2340       2350
AYLSGFDDAV EILPSLQKPK KISLKGSDGK SYIMMCKPKD DLRKDCRLME 
      2360       2370       2380       2390       2400
FNSLINKCLR KDAESRRREL HIRTYAVIPL NDECGIIEWV NNTAGFRNIL 
      2410       2420       2430       2440       2450
IKLYKEKGIY MGGKELRQCM LPKSAPLQEK LKVFKEALLP RHPPLFHEWF 
      2460       2470       2480       2490       2500
LRTFPDPTSW YNSRSAYCRS TAVMSMVGYI LGLGDRHGEN ILFDSLTGEC 
      2510       2520       2530       2540       2550
VHVDFNCLFN KGETFEVPEI VPFRLTHNMV NGMGPMGTEG LFRRACEVIM 
      2560       2570       2580       2590       2600
RLMREQRESL MSVLKPFLHD PLVEWSKPAR GSSKGQVNET GEVMNEKAKT 
      2610       2620       2630       2640       2650
HVLDIEQRLQ GVIKTRNRVK GLPLSIEGHV HYLIQEATDE NLLSQMYLGW 

APYM
Length:2,654
Mass (Da):301,459
Last modified:March 7, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF88E8A6541E6DD13
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti191Y → C in AAG34794 (PubMed:11069891).Curated1
Sequence conflicti249P → S in AAG34794 (PubMed:11069891).Curated1
Sequence conflicti434S → SS in AAW78662 (Ref. 3) Curated1
Sequence conflicti520D → N in AAW78662 (Ref. 3) Curated1
Sequence conflicti1047N → S in AAW78662 (Ref. 3) Curated1
Sequence conflicti1543L → P in AAW78662 (Ref. 3) Curated1
Sequence conflicti1785N → S in AAG40002 (PubMed:11137007).Curated1
Sequence conflicti1952T → A in AAW78662 (Ref. 3) Curated1
Sequence conflicti2082H → P in AAG34794 (PubMed:11069891).Curated1
Sequence conflicti2215M → T in AAW78662 (Ref. 3) Curated1
Sequence conflicti2362D → G in AAG34794 (PubMed:11069891).Curated1
Sequence conflicti2424S → N in AAG40002 (PubMed:11137007).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF320125 mRNA Translation: AAG40002.1
AF223644 mRNA Translation: AAG34794.1
AY882989 mRNA Translation: AAW78662.1

NCBI Reference Sequences

More...RefSeqi		NP_001082049.1, NM_001088580.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		398197

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		xla:398197

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF320125 mRNA Translation: AAG40002.1
AF223644 mRNA Translation: AAG34794.1
AY882989 mRNA Translation: AAW78662.1
RefSeqiNP_001082049.1, NM_001088580.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi99532, 3 interactors
IntActiQ9DE14, 2 interactors

PTM databases

iPTMnetiQ9DE14

Genome annotation databases

GeneIDi398197
KEGGixla:398197

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		398197
XenbaseiXB-GENE-1012725, atr.L

Phylogenomic databases

OMAiWMLLPHF
OrthoDBi80538at2759

Family and domain databases

Gene3Di1.10.1070.11, 1 hit
1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR003152, FATC_dom
IPR011009, Kinase-like_dom_sf
IPR000403, PI3/4_kinase_cat_dom
IPR036940, PI3/4_kinase_cat_sf
IPR018936, PI3/4_kinase_CS
IPR003151, PIK-rel_kinase_FAT
IPR014009, PIK_FAT
IPR011990, TPR-like_helical_dom_sf
IPR012993, UME
PfamiView protein in Pfam
PF02259, FAT, 1 hit
PF02260, FATC, 1 hit
PF00454, PI3_PI4_kinase, 1 hit
PF08064, UME, 1 hit
SMARTiView protein in SMART
SM01343, FATC, 1 hit
SM00146, PI3Kc, 1 hit
SM00802, UME, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
SSF48452, SSF48452, 1 hit
SSF56112, SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS51189, FAT, 1 hit
PS51190, FATC, 1 hit
PS00916, PI3_4_KINASE_2, 1 hit
PS50290, PI3_4_KINASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATR_XENLA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9DE14
Secondary accession number(s): Q5EGL8, Q9DDK7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: March 7, 2006
Last modified: February 10, 2021
This is version 102 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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