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Protein

Zinc finger protein 414

Gene

Znf414

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 123C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri135 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri166 – 190C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST25

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 414
Gene namesi
Name:Znf414
Synonyms:Zfp414
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1915641 Zfp414

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421641 – 299Zinc finger protein 414Add BLAST299

Proteomic databases

PaxDbiQ9DCK4
PRIDEiQ9DCK4

PTM databases

PhosphoSitePlusiQ9DCK4

Expressioni

Gene expression databases

BgeeiENSMUSG00000073423 Expressed in 222 organ(s), highest expression level in submandibular gland
CleanExiMM_ZFP414
ExpressionAtlasiQ9DCK4 baseline and differential
GenevisibleiQ9DCK4 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073259

Structurei

3D structure databases

ProteinModelPortaliQ9DCK4
SMRiQ9DCK4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri99 – 123C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri135 – 159C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri166 – 190C2H2-type 3; degeneratePROSITE-ProRule annotationAdd BLAST25

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00390000006876
HOGENOMiHOG000015387
HOVERGENiHBG083015
InParanoidiQ9DCK4
OMAiEGECPVF
OrthoDBiEOG091G0DB2
PhylomeDBiQ9DCK4
TreeFamiTF337512

Family and domain databases

InterProiView protein in InterPro
IPR039882 ZN414
IPR031799 Znf-C2H2_ribbon
IPR013087 Znf_C2H2_type
PANTHERiPTHR21695 PTHR21695, 1 hit
PfamiView protein in Pfam
PF15909 zf-C2H2_8, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9DCK4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEEPSRPSSD TLTTVESSSG EPDKEVASPD GAAPATFSSV EEPSPNPTAM
60 70 80 90 100
PPVWDHGGPL QQVAYPASDS CQTGSTNTGV GTNEDLRLPR RRPPPGKQIP
110 120 130 140 150
CSSPGCCLSF PSVRDLAQHL RTHCPPTQSL EGKLFRCSAL SCTESFPSMQ
160 170 180 190 200
ELVAHGKLHY KPNRYFKCEN CLLRFRTHRS LFKHLHVCID HGQNPAPPPP
210 220 230 240 250
PALDKEPPVP ERPPESDPSS SLGLPFPLLE PFTSAPTGPF LPYLNPAPFG
260 270 280 290
LSPPRLRPFL AATPGPPASS TAIWKKSQGA TSSPRRPQGG SDAPSGACR
Length:299
Mass (Da):31,988
Last modified:June 1, 2001 - v1
Checksum:iD68D58D7D28C5DDB
GO
Isoform 2 (identifier: Q9DCK4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-49: Missing.

Show »
Length:250
Mass (Da):27,029
Checksum:iADFD29E99470A6CD
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q4H9E9Q4H9_MOUSE
Zinc finger protein 414
Zfp414
229Annotation score:
E9Q9N0E9Q9N0_MOUSE
Zinc finger protein 414
Zfp414
21Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0194541 – 49Missing in isoform 2. 2 PublicationsAdd BLAST49

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002706 mRNA Translation: BAB22300.1
AK169869 mRNA Translation: BAE41424.1
AF528163 Genomic DNA Translation: AAO17381.1
BC038913 mRNA Translation: AAH38913.1
CCDSiCCDS37568.1 [Q9DCK4-1]
RefSeqiNP_080988.1, NM_026712.3 [Q9DCK4-1]
UniGeneiMm.181488

Genome annotation databases

EnsembliENSMUST00000073570; ENSMUSP00000073259; ENSMUSG00000073423 [Q9DCK4-1]
ENSMUST00000166627; ENSMUSP00000129423; ENSMUSG00000073423 [Q9DCK4-2]
GeneIDi328801
KEGGimmu:328801
UCSCiuc008byw.2 mouse [Q9DCK4-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002706 mRNA Translation: BAB22300.1
AK169869 mRNA Translation: BAE41424.1
AF528163 Genomic DNA Translation: AAO17381.1
BC038913 mRNA Translation: AAH38913.1
CCDSiCCDS37568.1 [Q9DCK4-1]
RefSeqiNP_080988.1, NM_026712.3 [Q9DCK4-1]
UniGeneiMm.181488

3D structure databases

ProteinModelPortaliQ9DCK4
SMRiQ9DCK4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073259

PTM databases

PhosphoSitePlusiQ9DCK4

Proteomic databases

PaxDbiQ9DCK4
PRIDEiQ9DCK4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000073570; ENSMUSP00000073259; ENSMUSG00000073423 [Q9DCK4-1]
ENSMUST00000166627; ENSMUSP00000129423; ENSMUSG00000073423 [Q9DCK4-2]
GeneIDi328801
KEGGimmu:328801
UCSCiuc008byw.2 mouse [Q9DCK4-1]

Organism-specific databases

CTDi328801
MGIiMGI:1915641 Zfp414

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00390000006876
HOGENOMiHOG000015387
HOVERGENiHBG083015
InParanoidiQ9DCK4
OMAiEGECPVF
OrthoDBiEOG091G0DB2
PhylomeDBiQ9DCK4
TreeFamiTF337512

Miscellaneous databases

PROiPR:Q9DCK4
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000073423 Expressed in 222 organ(s), highest expression level in submandibular gland
CleanExiMM_ZFP414
ExpressionAtlasiQ9DCK4 baseline and differential
GenevisibleiQ9DCK4 MM

Family and domain databases

InterProiView protein in InterPro
IPR039882 ZN414
IPR031799 Znf-C2H2_ribbon
IPR013087 Znf_C2H2_type
PANTHERiPTHR21695 PTHR21695, 1 hit
PfamiView protein in Pfam
PF15909 zf-C2H2_8, 1 hit
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 2 hits
PS50157 ZINC_FINGER_C2H2_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZN414_MOUSE
AccessioniPrimary (citable) accession number: Q9DCK4
Secondary accession number(s): Q8CHU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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