Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - Q9DC71 (RT15_MOUSE)

Entry version 160 (23 Feb 2022)
Sequence version 2 (04 May 2001)
Previous versions | rss
Add a publicationFeedback
Protein

28S ribosomal protein S15, mitochondrial

Gene

Mrps15

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-5389840, Mitochondrial translation elongation
R-MMU-5419276, Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
28S ribosomal protein S15, mitochondrial
Short name:
MRP-S15
Short name:
S15mt
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mrps15
Synonyms:Rpms15
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1913657, Mrps15

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000028861

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 57MitochondrionSequence analysisAdd BLAST57
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003061558 – 25828S ribosomal protein S15, mitochondrialAdd BLAST201

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q9DC71

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q9DC71

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q9DC71

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q9DC71

PeptideAtlas

More...PeptideAtlasi		Q9DC71

PRoteomics IDEntifications database

More...PRIDEi		Q9DC71

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		261001

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q9DC71

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q9DC71

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000028861, Expressed in heart and 310 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q9DC71, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins (By similarity).

Interacts with METTL17 (PubMed:31487196).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		211451, 13 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5301, 28S mitochondrial small ribosomal subunit

Protein interaction database and analysis system

More...IntActi		Q9DC71, 2 interactors

Molecular INTeraction database

More...MINTi		Q9DC71

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000030675

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q9DC71, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q9DC71

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni229 – 258DisorderedSequence analysisAdd BLAST30

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uS15 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2815, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000001737

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_094627_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q9DC71

Identification of Orthologs from Complete Genome Data

More...OMAi		RYLQMSI

Database of Orthologous Groups

More...OrthoDBi		1539741at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q9DC71

TreeFam database of animal gene trees

More...TreeFami		TF319038

Family and domain databases

Conserved Domains Database

More...CDDi		cd00353, Ribosomal_S15p_S13e, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01343_B, Ribosomal_S15_B, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000589, Ribosomal_S15
IPR005290, Ribosomal_S15_bac-type
IPR009068, S15_NS1_RNA-bd

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00312, Ribosomal_S15, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01387, Ribosomal_S15, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47060, SSF47060, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q9DC71-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRAAWRALS SVRAQAVTRA PVPALRGGSS ASLLSARCGL QPPSLLRAAR 
        60         70         80         90        100
AYAAVQKPVQ PKQDDEPPSS AFIKEYKDII PNIEKVDDVV KRILSLEMAS 
       110        120        130        140        150
RKEKLKIKQE QLMNKIVENP EDSRTLEAQI IALTVRIRNY EEHMQKHRKD 
       160        170        180        190        200
KAHKRHLLMS IDRRKKLLKI LRQTNYDVFE KTCKELGVEY TLPPLHFQKV 
       210        220        230        240        250
HRRFLAKKAL CIRVYQEVQK LKKQKRALKA AAAAAKKEKN EGVPENPSNA 

VPEKTQVN
Length:258
Mass (Da):29,464
Last modified:May 4, 2001 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i98FF04FA2EE78D96
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti139N → D in BAC34235 (PubMed:16141072).Curated1
Sequence conflicti180E → G in BAB26857 (PubMed:16141072).Curated1
Sequence conflicti241E → G in BAB41000 (PubMed:11402041).Curated1
Sequence conflicti241E → G in BAB22586 (PubMed:16141072).Curated1
Sequence conflicti251V → L in AAH55861 (PubMed:15489334).Curated1
Sequence conflicti257V → M in BAB26857 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB049947 mRNA Translation: BAB41000.1
AK003126 mRNA Translation: BAB22586.1
AK010330 mRNA Translation: BAB26857.1
AK008623 mRNA Translation: BAB25785.1
AK050396 mRNA Translation: BAC34235.1
BC029193 mRNA Translation: AAH29193.1
BC055861 mRNA Translation: AAH55861.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS18641.1

NCBI Reference Sequences

More...RefSeqi		NP_079820.2, NM_025544.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000030675; ENSMUSP00000030675; ENSMUSG00000028861

Database of genes from NCBI RefSeq genomes

More...GeneIDi		66407

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:66407

UCSC genome browser

More...UCSCi		uc008usf.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049947 mRNA Translation: BAB41000.1
AK003126 mRNA Translation: BAB22586.1
AK010330 mRNA Translation: BAB26857.1
AK008623 mRNA Translation: BAB25785.1
AK050396 mRNA Translation: BAC34235.1
BC029193 mRNA Translation: AAH29193.1
BC055861 mRNA Translation: AAH55861.1
CCDSiCCDS18641.1
RefSeqiNP_079820.2, NM_025544.2

3D structure databases

SMRiQ9DC71
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi211451, 13 interactors
ComplexPortaliCPX-5301, 28S mitochondrial small ribosomal subunit
IntActiQ9DC71, 2 interactors
MINTiQ9DC71
STRINGi10090.ENSMUSP00000030675

PTM databases

iPTMnetiQ9DC71
PhosphoSitePlusiQ9DC71

Proteomic databases

EPDiQ9DC71
jPOSTiQ9DC71
MaxQBiQ9DC71
PaxDbiQ9DC71
PeptideAtlasiQ9DC71
PRIDEiQ9DC71
ProteomicsDBi261001

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31697, 178 antibodies from 27 providers

Genome annotation databases

EnsembliENSMUST00000030675; ENSMUSP00000030675; ENSMUSG00000028861
GeneIDi66407
KEGGimmu:66407
UCSCiuc008usf.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64960
MGIiMGI:1913657, Mrps15
VEuPathDBiHostDB:ENSMUSG00000028861

Phylogenomic databases

eggNOGiKOG2815, Eukaryota
GeneTreeiENSGT00390000001737
HOGENOMiCLU_094627_0_0_1
InParanoidiQ9DC71
OMAiRYLQMSI
OrthoDBi1539741at2759
PhylomeDBiQ9DC71
TreeFamiTF319038

Enzyme and pathway databases

ReactomeiR-MMU-5389840, Mitochondrial translation elongation
R-MMU-5419276, Mitochondrial translation termination

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		66407, 21 hits in 65 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Mrps15, mouse

Protein Ontology

More...PROi		PR:Q9DC71
RNActiQ9DC71, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000028861, Expressed in heart and 310 other tissues
GenevisibleiQ9DC71, MM

Family and domain databases

CDDicd00353, Ribosomal_S15p_S13e, 1 hit
HAMAPiMF_01343_B, Ribosomal_S15_B, 1 hit
InterProiView protein in InterPro
IPR000589, Ribosomal_S15
IPR005290, Ribosomal_S15_bac-type
IPR009068, S15_NS1_RNA-bd
PfamiView protein in Pfam
PF00312, Ribosomal_S15, 1 hit
SMARTiView protein in SMART
SM01387, Ribosomal_S15, 1 hit
SUPFAMiSSF47060, SSF47060, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRT15_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9DC71
Secondary accession number(s): Q7TMG9
, Q8C7F1, Q9CVE0, Q9CWX1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: May 4, 2001
Last modified: February 23, 2022
This is version 160 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again