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Entry version 129 (12 Aug 2020)
Sequence version 3 (18 Sep 2013)
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Protein

Copine-8

Gene

Cpne8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.By similarity

Caution

It is uncertain whether Met-1 or Met-14 is the initiator.Curated

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+PROSITE-ProRule annotationNote: Binds 3 Ca2+ ions per C2 domain.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi52Calcium 1PROSITE-ProRule annotation1
Metal bindingi52Calcium 2PROSITE-ProRule annotation1
Metal bindingi58Calcium 1PROSITE-ProRule annotation1
Metal bindingi112Calcium 1PROSITE-ProRule annotation1
Metal bindingi112Calcium 2PROSITE-ProRule annotation1
Metal bindingi114Calcium 1PROSITE-ProRule annotation1
Metal bindingi114Calcium 2PROSITE-ProRule annotation1
Metal bindingi114Calcium 3PROSITE-ProRule annotation1
Metal bindingi117Calcium 3PROSITE-ProRule annotation1
Metal bindingi122Calcium 3; via carbonyl oxygenPROSITE-ProRule annotation1
Metal bindingi124Calcium 2PROSITE-ProRule annotation1
Metal bindingi124Calcium 3PROSITE-ProRule annotation1
Metal bindingi186Calcium 4PROSITE-ProRule annotation1
Metal bindingi186Calcium 5PROSITE-ProRule annotation1
Metal bindingi192Calcium 4PROSITE-ProRule annotation1
Metal bindingi248Calcium 4PROSITE-ProRule annotation1
Metal bindingi248Calcium 5PROSITE-ProRule annotation1
Metal bindingi250Calcium 4PROSITE-ProRule annotation1
Metal bindingi250Calcium 5PROSITE-ProRule annotation1
Metal bindingi256Calcium 5PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalcium, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Copine-8Curated
Alternative name(s):
Copine VIIIImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cpne8Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1914121, Cpne8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001448501 – 577Copine-8Add BLAST577

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei273PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9DC53

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9DC53

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9DC53

PeptideAtlas

More...
PeptideAtlasi
Q9DC53

PRoteomics IDEntifications database

More...
PRIDEi
Q9DC53

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9DC53

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9DC53

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000052560, Expressed in Ammon's horn and 248 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9DC53, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9DC53, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q9DC53, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000067774

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9DC53, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9DC53

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini19 – 146C2 1PROSITE-ProRule annotationAdd BLAST128
Domaini155 – 278C2 2PROSITE-ProRule annotationAdd BLAST124
Domaini322 – 523VWFAPROSITE-ProRule annotationAdd BLAST202

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the copine family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1327, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159679

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_020452_3_2_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9DC53

Identification of Orthologs from Complete Genome Data

More...
OMAi
PYTPPIH

Database of Orthologous Groups

More...
OrthoDBi
1067545at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9DC53

TreeFam database of animal gene trees

More...
TreeFami
TF316419

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04047, C2B_Copine, 1 hit
cd01459, vWA_copine_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR037768, C2B_Copine
IPR010734, Copine
IPR002035, VWF_A
IPR036465, vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 2 hits
PF07002, Copine, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 2 hits
SM00327, VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53300, SSF53300, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 2 hits
PS50234, VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9DC53-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWARDKCSVP QLEMDSRYTS ATGIGDLNQL SAAIPATRVE VSVSCRNLLD
60 70 80 90 100
RDTFSKSDPI CVLYTQAVGN KEWREFGRTE VIDNTLNPDF VRKFILDYFF
110 120 130 140 150
EERENLRFDL YDVDSKSPNL SKHDFLGQVF CTLGEIVGSQ GSRLEKPIVG
160 170 180 190 200
IPGRKCGTII LTAEELNCCR DAVLMQFCAN KLDKKDFFGK SDPFLVFYRS
210 220 230 240 250
NEDGSFTICH KTEVVKNTLN PVWQAFKISV RALCNGDYDR TIKVEVYDWD
260 270 280 290 300
RDGSHDFIGE FTTSYRELAR GQSQFNVYEV VNPKKKGKKK KYTNSGTVTL
310 320 330 340 350
LSFLVETEVS FLDYIKGGTQ INFTVAIDFT ASNGNPAQPT SLHYMNPYQL
360 370 380 390 400
NAYGMALKAV GEIVQDYDSD KMFPALGFGA KLPPDGRISH EFALNGNPQN
410 420 430 440 450
PYCDGIEGVM EAYYRSLKSV QLYGPTNFAP VINHVARYAS SVKDGSQYFV
460 470 480 490 500
LLIVTDGVIS DMAQTKESIV NASKLPMSII IVGVGPAEFD AMVELDGDDV
510 520 530 540 550
RVSSRGKYAE RDIVQFVPFR DYIDRSGNHI LSMARLAKDV LAEIPEQFLS
560 570
YMRARGIKPS PAPPPYTPPT HVLQTQI
Length:577
Mass (Da):64,667
Last modified:September 18, 2013 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6287BF291AA0A0F4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9DB19Q9DB19_MOUSE
Copine VIII
Cpne8
104Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q9CYR4Q9CYR4_MOUSE
Copine-8
Cpne8
157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK004559 mRNA Translation: BAB23372.1
AK010227 mRNA Translation: BAB26781.1
AC099572 Genomic DNA No translation available.
AC113493 Genomic DNA No translation available.
AC116812 Genomic DNA No translation available.
CH466550 Genomic DNA Translation: EDL04322.1
BC138745 mRNA Translation: AAI38746.1
BC138746 mRNA Translation: AAI38747.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS27758.1

NCBI Reference Sequences

More...
RefSeqi
NP_080091.1, NM_025815.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000064391; ENSMUSP00000067774; ENSMUSG00000052560

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
66871

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:66871

UCSC genome browser

More...
UCSCi
uc007xhn.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004559 mRNA Translation: BAB23372.1
AK010227 mRNA Translation: BAB26781.1
AC099572 Genomic DNA No translation available.
AC113493 Genomic DNA No translation available.
AC116812 Genomic DNA No translation available.
CH466550 Genomic DNA Translation: EDL04322.1
BC138745 mRNA Translation: AAI38746.1
BC138746 mRNA Translation: AAI38747.1
CCDSiCCDS27758.1
RefSeqiNP_080091.1, NM_025815.2

3D structure databases

SMRiQ9DC53
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ9DC53, 1 interactor
STRINGi10090.ENSMUSP00000067774

PTM databases

iPTMnetiQ9DC53
PhosphoSitePlusiQ9DC53

Proteomic databases

jPOSTiQ9DC53
MaxQBiQ9DC53
PaxDbiQ9DC53
PeptideAtlasiQ9DC53
PRIDEiQ9DC53

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
42502, 138 antibodies

Genome annotation databases

EnsembliENSMUST00000064391; ENSMUSP00000067774; ENSMUSG00000052560
GeneIDi66871
KEGGimmu:66871
UCSCiuc007xhn.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
144402
MGIiMGI:1914121, Cpne8

Phylogenomic databases

eggNOGiKOG1327, Eukaryota
GeneTreeiENSGT00940000159679
HOGENOMiCLU_020452_3_2_1
InParanoidiQ9DC53
OMAiPYTPPIH
OrthoDBi1067545at2759
PhylomeDBiQ9DC53
TreeFamiTF316419

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
66871, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Cpne8, mouse

Protein Ontology

More...
PROi
PR:Q9DC53
RNActiQ9DC53, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000052560, Expressed in Ammon's horn and 248 other tissues
ExpressionAtlasiQ9DC53, baseline and differential
GenevisibleiQ9DC53, MM

Family and domain databases

CDDicd04047, C2B_Copine, 1 hit
cd01459, vWA_copine_like, 1 hit
Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR037768, C2B_Copine
IPR010734, Copine
IPR002035, VWF_A
IPR036465, vWFA_dom_sf
PfamiView protein in Pfam
PF00168, C2, 2 hits
PF07002, Copine, 1 hit
SMARTiView protein in SMART
SM00239, C2, 2 hits
SM00327, VWA, 1 hit
SUPFAMiSSF53300, SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 2 hits
PS50234, VWFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPNE8_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9DC53
Secondary accession number(s): B2RS65, Q9CUZ8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: September 18, 2013
Last modified: August 12, 2020
This is version 129 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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