UniProtKB - Q9DBY0 (FOXP4_MOUSE)

BLAST

>sp|Q9DBY0|FOXP4_MOUSE Forkhead box protein P4 OS=Mus musculus OX=10090 GN=Foxp4 PE=1 SV=1
MMVESASETIRSAPSGQNGVGSLSAQADGGGGAGTAGTAPAAGRDASGREAASGGADSNG
EMSPAELLHFQQQQALQVARQFLLQQASSLNSPGNNDSKQSASAVQVPVSVAMMSQQMLT
PQQMQQILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKQQPKEALGN
KQLAFQQQLLQMQQLQQQHLLNLQRQGLVSLQPSQASGPLQALPQAVCPTDLPQLWKGEG
APGQPAEDSGRQEGLDLASTAVTATSFASPPKVSPPLSHHPLPNGQPTVLTSRRDSSSHE
ETPSSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQ
LAKESERLQAMMAHLHMRPSEPKPFSQPVTVSADPFPDGLVHPPTSAAAPVTPLRPPGLG
SASLHSGGPARRRSNDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQL
TLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRP
PKMTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLSNPGMLNPGSASSLLPLSQEDL
GVPGEPLPSNGSSSPPRLSPPQYSHQIQVKEEPAEAEEDRRPGPPLGAPNPSTVGPPEDR
DLEEDLGGEDMPSQPCPLIPGWKPSLLHLSYCVKPKFTVSVGSKTPSSPLPPPPRVQGSY
SLPPCSYLAYGDMRGQNPAPSPGLLSGVGGGLFRCLHRTKSPSLPGVWILAAELETMRFH
RPPMGDPQPKTADWV

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History
Entry version 136 (07 Nov 2018)
Sequence version 1 (01 Jun 2001)
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Protein

Forkhead box protein P4

Gene

Foxp4

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Transcriptional repressor that represses lung-specific expression.1 Publication

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	312 – 337	C2H2-typeSequence analysisAdd BLAST		26
DNA bindingⁱ	459 – 549	Fork-headPROSITE-ProRule annotationAdd BLAST		91

GO - Molecular functionⁱ

DNA binding
Source: MGI
Inferred from direct assayⁱ
- 14701752
metal ion binding Source: UniProtKB-KW
protein heterodimerization activity
Source: MGI
Inferred from physical interactionⁱ
- 14701752
protein homodimerization activity
Source: MGI
Inferred from physical interactionⁱ
- 14701752
proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific
Source: NTNU_SB
Inferred from direct assayⁱ
- 14701752
RNA polymerase II proximal promoter sequence-specific DNA binding
Source: NTNU_SB
Inferred from mutant phenotypeⁱ
- 14701752

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

embryonic foregut morphogenesis
Source: MGI
Inferred from mutant phenotypeⁱ
- 15361625
heart development
Source: MGI
Inferred from mutant phenotypeⁱ
- 15361625
lung secretory cell differentiation
Source: MGI
Inferred from genetic interactionⁱ
- 22675208
negative regulation of lung goblet cell differentiation
Source: MGI
Inferred from genetic interactionⁱ
- 22675208
negative regulation of transcription by RNA polymerase II
Source: NTNU_SB
Inferred from direct assayⁱ
- 14701752
regulation of lung goblet cell differentiation
Source: MGI
Inferred from genetic interactionⁱ
- 22675208

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding, Repressor
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Forkhead box protein P4 Alternative name(s): Fork head-related protein-like A Short name: mFKHLA
Gene namesⁱ	Name:Foxp4Imported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 17

Organism-specific databases

MGIⁱ	MGI:1921373 Foxp4

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	366	Missing : Loss of dimerization. Almost complete loss of DNA-binding. Reduced transcriptional repression activity. 1 Publication		1

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000247653	1 – 795	Forkhead box protein P4Add BLAST		795

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	58	PhosphoserineBy similarity	1
Modified residueⁱ	92	PhosphoserineBy similarity	1
Cross-linkⁱ	181	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	383	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	546	PhosphoserineBy similarity	1

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbⁱ	Q9DBY0
PRIDEⁱ	Q9DBY0

PTM databases

iPTMnetⁱ	Q9DBY0
PhosphoSitePlusⁱ	Q9DBY0

Expressionⁱ

Tissue specificityⁱ

Expressed in the adult heart, brain, spleen lung, liver, kidney and testes.2 Publications

Developmental stageⁱ

Expressed predominantly in the lung and brain during embryogenesis. Expressed in the lung epithelium and the mesenchyme immediately adjacent to the epithelium from 10.5 dpc. At 9.5 dpc, expressed in the foregut endoderm but not in the heart. At 16.5 and 18.5 dpc, expressed in both the proximal and distal airway epithelium. Also expressed in the developing gut. In the hindgut, primarily expressed in epithelial cells of the intestine and stomach. Expressed in the brain in a dynamic pattern. At 14.5 dpc, expressed at high levels in the intermediate zone of the neopallial cortex with lower levels in the surrounding cells. By 16.5 dpc, no longer expressed in the intermediate zone, but still present in the surrounding cells of the neopallial cortex.2 Publications

Gene expression databases

Bgeeⁱ	ENSMUSG00000023991 Expressed in 245 organ(s), highest expression level in head
CleanExⁱ	MM_FOXP4
ExpressionAtlasⁱ	Q9DBY0 baseline and differential
Genevisibleⁱ	Q9DBY0 MM

Interactionⁱ

Subunit structureⁱ

Forms homodimers and heterodimers with FOXP1 and FOXP2. Dimerization is required for DNA-binding.1 Publication

GO - Molecular functionⁱ

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	216509, 2 interactors
IntActⁱ	Q9DBY0, 1 interactor
STRINGⁱ	10090.ENSMUSP00000094916

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9DBY0
SMRⁱ	Q9DBY0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	354 – 375	Leucine-zipperAdd BLAST		22

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	71 – 225	Gln-richSequence analysisAdd BLAST		155
Compositional biasⁱ	603 – 724	Pro-richSequence analysisAdd BLAST		122

Domainⁱ

The leucine-zipper is required for dimerization and transcriptional repression.1 Publication

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	312 – 337	C2H2-typeSequence analysisAdd BLAST		26

Keywords - Domainⁱ

Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG4385 Eukaryota COG5025 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150842
HOGENOMⁱ	HOG000092089
HOVERGENⁱ	HBG051657
InParanoidⁱ	Q9DBY0
KEGG Orthology (KO) More...KOⁱ	K09409
OMAⁱ	DEHEYQK
PhylomeDBⁱ	Q9DBY0
TreeFamⁱ	TF326978

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00059 FH, 1 hit
Gene3Dⁱ	1.10.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR001766 Fork_head_dom IPR032354 FOXP-CC IPR030456 TF_fork_head_CS_2 IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00250 Forkhead, 1 hit PF16159 FOXP-CC, 1 hit
PRINTSⁱ	PR00053 FORKHEAD
SMARTⁱ	View protein in SMART SM00339 FH, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit
PROSITEⁱ	View protein in PROSITE PS00658 FORK_HEAD_2, 1 hit PS50039 FORK_HEAD_3, 1 hit PS00028 ZINC_FINGER_C2H2_1, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show all Align All

Isoform 11 Publication (identifier: Q9DBY0-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MMVESASETI RSAPSGQNGV GSLSAQADGG GGAGTAGTAP AAGRDASGRE 
        60         70         80         90        100
AASGGADSNG EMSPAELLHF QQQQALQVAR QFLLQQASSL NSPGNNDSKQ 
       110        120        130        140        150
SASAVQVPVS VAMMSQQMLT PQQMQQILSP PQLQALLQQQ QALMLQQLQE 
       160        170        180        190        200
YYKKQQEQLH LQLLTQQQAG KQQPKEALGN KQLAFQQQLL QMQQLQQQHL 
       210        220        230        240        250
LNLQRQGLVS LQPSQASGPL QALPQAVCPT DLPQLWKGEG APGQPAEDSG 
       260        270        280        290        300
RQEGLDLAST AVTATSFASP PKVSPPLSHH PLPNGQPTVL TSRRDSSSHE 
       310        320        330        340        350
ETPSSHPLYG HGECKWPGCE TLCEDLGQFI KHLNTEHALD DRSTAQCRVQ 
       360        370        380        390        400
MQVVQQLEIQ LAKESERLQA MMAHLHMRPS EPKPFSQPVT VSADPFPDGL 
       410        420        430        440        450
VHPPTSAAAP VTPLRPPGLG SASLHSGGPA RRRSNDKFCS PISSELAQNH 
       460        470        480        490        500
EFYKNADVRP PFTYASLIRQ AILETPDRQL TLNEIYNWFT RMFAYFRRNT 
       510        520        530        540        550
ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEREYQKRRP PKMTGSPTLV 
       560        570        580        590        600
KNMISGLSYG ALNASYQAAL AESSFPLLSN PGMLNPGSAS SLLPLSQEDL 
       610        620        630        640        650
GVPGEPLPSN GSSSPPRLSP PQYSHQIQVK EEPAEAEEDR RPGPPLGAPN 
       660        670        680        690        700
PSTVGPPEDR DLEEDLGGED MPSQPCPLIP GWKPSLLHLS YCVKPKFTVS 
       710        720        730        740        750
VGSKTPSSPL PPPPRVQGSY SLPPCSYLAY GDMRGQNPAP SPGLLSGVGG 
       760        770        780        790 
GLFRCLHRTK SPSLPGVWIL AAELETMRFH RPPMGDPQPK TADWV

Note: No experimental confirmation available.Curated

Length:795

Mass (Da):85,981

Last modified:June 1, 2001 - v1

Checksum:ⁱ860AE60AAD3742CE

Isoform 21 Publication (identifier: Q9DBY0-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
672-672: P → S
673-795: Missing.

« Hide

        10         20         30         40         50
MMVESASETI RSAPSGQNGV GSLSAQADGG GGAGTAGTAP AAGRDASGRE 
        60         70         80         90        100
AASGGADSNG EMSPAELLHF QQQQALQVAR QFLLQQASSL NSPGNNDSKQ 
       110        120        130        140        150
SASAVQVPVS VAMMSQQMLT PQQMQQILSP PQLQALLQQQ QALMLQQLQE 
       160        170        180        190        200
YYKKQQEQLH LQLLTQQQAG KQQPKEALGN KQLAFQQQLL QMQQLQQQHL 
       210        220        230        240        250
LNLQRQGLVS LQPSQASGPL QALPQAVCPT DLPQLWKGEG APGQPAEDSG 
       260        270        280        290        300
RQEGLDLAST AVTATSFASP PKVSPPLSHH PLPNGQPTVL TSRRDSSSHE 
       310        320        330        340        350
ETPSSHPLYG HGECKWPGCE TLCEDLGQFI KHLNTEHALD DRSTAQCRVQ 
       360        370        380        390        400
MQVVQQLEIQ LAKESERLQA MMAHLHMRPS EPKPFSQPVT VSADPFPDGL 
       410        420        430        440        450
VHPPTSAAAP VTPLRPPGLG SASLHSGGPA RRRSNDKFCS PISSELAQNH 
       460        470        480        490        500
EFYKNADVRP PFTYASLIRQ AILETPDRQL TLNEIYNWFT RMFAYFRRNT 
       510        520        530        540        550
ATWKNAVRHN LSLHKCFVRV ENVKGAVWTV DEREYQKRRP PKMTGSPTLV 
       560        570        580        590        600
KNMISGLSYG ALNASYQAAL AESSFPLLSN PGMLNPGSAS SLLPLSQEDL 
       610        620        630        640        650
GVPGEPLPSN GSSSPPRLSP PQYSHQIQVK EEPAEAEEDR RPGPPLGAPN 
       660        670 
PSTVGPPEDR DLEEDLGGED MS

Show »

Length:672

Mass (Da):72,759

Checksum:ⁱ8B89F59EF85FC768

Isoform 31 Publication (identifier: Q9DBY0-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
     388-388: P → PLNPVPGSSSFSK
     672-672: P → S
     673-795: Missing.

« Hide

        10         20         30         40         50
MMVESASETI RSAPSGQNGV GSLSAQADGG GGAGTAGTAP AAGRDASGRE 
        60         70         80         90        100
AASGGADSNG EMSPAELLHF QQQQALQVAR QFLLQQASSL NSPGNNDSKQ 
       110        120        130        140        150
SASAVQVPVS VAMMSQQMLT PQQMQQILSP PQLQALLQQQ QALMLQQLQE 
       160        170        180        190        200
YYKKQQEQLH LQLLTQQQAG KQQPKEALGN KQLAFQQQLL QMQQLQQQHL 
       210        220        230        240        250
LNLQRQGLVS LQPSQASGPL QALPQAVCPT DLPQLWKGEG APGQPAEDSG 
       260        270        280        290        300
RQEGLDLAST AVTATSFASP PKVSPPLSHH PLPNGQPTVL TSRRDSSSHE 
       310        320        330        340        350
ETPSSHPLYG HGECKWPGCE TLCEDLGQFI KHLNTEHALD DRSTAQCRVQ 
       360        370        380        390        400
MQVVQQLEIQ LAKESERLQA MMAHLHMRPS EPKPFSQPLN PVPGSSSFSK 
       410        420        430        440        450
VTVSADPFPD GLVHPPTSAA APVTPLRPPG LGSASLHSGG PARRRSNDKF 
       460        470        480        490        500
CSPISSELAQ NHEFYKNADV RPPFTYASLI RQAILETPDR QLTLNEIYNW 
       510        520        530        540        550
FTRMFAYFRR NTATWKNAVR HNLSLHKCFV RVENVKGAVW TVDEREYQKR 
       560        570        580        590        600
RPPKMTGSPT LVKNMISGLS YGALNASYQA ALAESSFPLL SNPGMLNPGS 
       610        620        630        640        650
ASSLLPLSQE DLGVPGEPLP SNGSSSPPRL SPPQYSHQIQ VKEEPAEAEE 
       660        670        680 
DRRPGPPLGA PNPSTVGPPE DRDLEEDLGG EDMS

Show »

Length:684

Mass (Da):73,960

Checksum:ⁱA7CFBE31E1C09A09

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

D3Z726	D3Z726_MOUSE	Forkhead box protein P4 Forkhead box protein P4	Foxp4	683	Annotation score:
A0A0R4J161	A0A0R4J161_MOUSE	Forkhead box protein P4 Forkhead box protein P4	Foxp4	685	Annotation score:
A0A0R4J1I5	A0A0R4J1I5_MOUSE	Forkhead box protein P4 Forkhead box protein P4	Foxp4	673	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	226	A → AA in AAN08624 (Ref. 2) Curated	1
Sequence conflictⁱ	226	A → AA in AAH43702 (PubMed:15489334).Curated	1
Sequence conflictⁱ	226	A → AA in AAH52407 (PubMed:15489334).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_052129	388	P → PLNPVPGSSSFSK in isoform 3. 2 Publications	1
Alternative sequenceⁱVSP_052130	672	P → S in isoform 2 and isoform 3. 3 Publications	1
Alternative sequenceⁱVSP_052131	673 – 795	Missing in isoform 2 and isoform 3. 3 PublicationsAdd BLAST	123

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY135029 mRNA Translation: AAN08624.1 AB052766 mRNA Translation: BAC53799.1 AK004693 mRNA Translation: BAB23479.1 BC043702 mRNA Translation: AAH43702.1 BC052407 mRNA Translation: AAH52407.1 BC057110 mRNA Translation: AAH57110.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS50135.1 [Q9DBY0-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001104294.1, NM_001110824.1 NP_001104295.1, NM_001110825.1 NP_083043.2, NM_028767.2 [Q9DBY0-2]
UniGeneⁱ	Mm.240062

Genome annotation databases

Ensemblⁱ	ENSMUST00000113265; ENSMUSP00000108890; ENSMUSG00000023991 [Q9DBY0-2] ENSMUST00000229858; ENSMUSP00000155078; ENSMUSG00000116496 [Q9DBY0-2]
GeneIDⁱ	74123
KEGGⁱ	mmu:74123
UCSC genome browser More...UCSCⁱ	uc008cwm.2 mouse [Q9DBY0-3] uc008cwn.2 mouse [Q9DBY0-2]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9DBY0-2	Isoform 3 of Forkhead box protein P4		MOUSE		684	UniRef90_Q9DBY0-3
Forkhead box protein P4		HUMAN		680
Forkhead box P4		BOVIN		825
Uncharacterized protein		LOXAF		717
Forkhead box protein P4		HETGA		688
+328
Q9DBY0-3	Forkhead box protein P4		HUMAN		680	UniRef90_Q9DBY0-3
Forkhead box P4		BOVIN		825
Uncharacterized protein		LOXAF		717
Forkhead box protein P4		HETGA		688
Uncharacterized protein		NEOLE		688
+328

Protein	Similar proteins		Species	Score	Length	Source
Q9DBY0	Forkhead box protein P1		CHICK		686	UniRef50_Q9DBY0
Forkhead box protein P4		HUMAN		680
forkhead box protein P4-like isoform X8		SALSA		701
Forkhead box protein P2		GORGO		666
forkhead box protein P4 isoform X3		TARSY		619
+860

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AY135029 mRNA Translation: AAN08624.1 AB052766 mRNA Translation: BAC53799.1 AK004693 mRNA Translation: BAB23479.1 BC043702 mRNA Translation: AAH43702.1 BC052407 mRNA Translation: AAH52407.1 BC057110 mRNA Translation: AAH57110.1
CCDSⁱ	CCDS50135.1 [Q9DBY0-2]
RefSeqⁱ	NP_001104294.1, NM_001110824.1 NP_001104295.1, NM_001110825.1 NP_083043.2, NM_028767.2 [Q9DBY0-2]
UniGeneⁱ	Mm.240062

3D structure databases

ProteinModelPortalⁱ	Q9DBY0
SMRⁱ	Q9DBY0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	216509, 2 interactors
IntActⁱ	Q9DBY0, 1 interactor
STRINGⁱ	10090.ENSMUSP00000094916

PTM databases

iPTMnetⁱ	Q9DBY0
PhosphoSitePlusⁱ	Q9DBY0

Proteomic databases

PaxDbⁱ	Q9DBY0
PRIDEⁱ	Q9DBY0

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000113265; ENSMUSP00000108890; ENSMUSG00000023991 [Q9DBY0-2] ENSMUST00000229858; ENSMUSP00000155078; ENSMUSG00000116496 [Q9DBY0-2]
GeneIDⁱ	74123
KEGGⁱ	mmu:74123
UCSCⁱ	uc008cwm.2 mouse [Q9DBY0-3] uc008cwn.2 mouse [Q9DBY0-2]

Organism-specific databases

CTDⁱ	116113
MGIⁱ	MGI:1921373 Foxp4

Phylogenomic databases

eggNOGⁱ	KOG4385 Eukaryota COG5025 LUCA
GeneTreeⁱ	ENSGT00930000150842
HOGENOMⁱ	HOG000092089
HOVERGENⁱ	HBG051657
InParanoidⁱ	Q9DBY0
KOⁱ	K09409
OMAⁱ	DEHEYQK
PhylomeDBⁱ	Q9DBY0
TreeFamⁱ	TF326978

Miscellaneous databases

ChiTaRSⁱ	Foxp4 mouse
Protein Ontology More...PROⁱ	PR:Q9DBY0
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000023991 Expressed in 245 organ(s), highest expression level in head
CleanExⁱ	MM_FOXP4
ExpressionAtlasⁱ	Q9DBY0 baseline and differential
Genevisibleⁱ	Q9DBY0 MM

Family and domain databases

CDDⁱ	cd00059 FH, 1 hit
Gene3Dⁱ	1.10.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR001766 Fork_head_dom IPR032354 FOXP-CC IPR030456 TF_fork_head_CS_2 IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
Pfamⁱ	View protein in Pfam PF00250 Forkhead, 1 hit PF16159 FOXP-CC, 1 hit
PRINTSⁱ	PR00053 FORKHEAD
SMARTⁱ	View protein in SMART SM00339 FH, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit
PROSITEⁱ	View protein in PROSITE PS00658 FORK_HEAD_2, 1 hit PS50039 FORK_HEAD_3, 1 hit PS00028 ZINC_FINGER_C2H2_1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	FOXP4_MOUSE
Accessionⁱ	Q9DBY0Primary (citable) accession number: Q9DBY0 Secondary accession number(s): Q80V92, Q8CG10, Q8CIS1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
	Last sequence update:	June 1, 2001
	Last modified:	November 7, 2018
	This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9DBY0 (FOXP4_MOUSE)

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Forkhead box protein P4

Foxp4

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Compositional bias

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ