Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Acyl-coenzyme A oxidase-like protein

Gene

Acoxl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

FADBy similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi376 – 381FADBy similarity6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandFAD, Flavoprotein

Enzyme and pathway databases

ReactomeiR-MMU-389887 Beta-oxidation of pristanoyl-CoA

Names & Taxonomyi

Protein namesi
Recommended name:
Acyl-coenzyme A oxidase-like protein (EC:1.3.3.-)
Short name:
Acyl-CoA oxidase-like protein
Gene namesi
Name:Acoxl
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1921371 Acoxl

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003051011 – 632Acyl-coenzyme A oxidase-like proteinAdd BLAST632

Proteomic databases

PaxDbiQ9DBS4
PRIDEiQ9DBS4

PTM databases

iPTMnetiQ9DBS4
PhosphoSitePlusiQ9DBS4

Expressioni

Gene expression databases

BgeeiENSMUSG00000027380
CleanExiMM_ACOXL
GenevisibleiQ9DBS4 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000028859

Structurei

3D structure databases

ProteinModelPortaliQ9DBS4
SMRiQ9DBS4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the acyl-CoA oxidase family.Curated

Phylogenomic databases

eggNOGiKOG0135 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00530000062919
HOGENOMiHOG000245077
HOVERGENiHBG105796
InParanoidiQ9DBS4
OMAiICREACG
OrthoDBiEOG091G03TE
PhylomeDBiQ9DBS4
TreeFamiTF354292

Family and domain databases

InterProiView protein in InterPro
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR012258 Acyl-CoA_oxidase
IPR002655 Acyl-CoA_oxidase_C
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF01756 ACOX, 1 hit
PF00441 Acyl-CoA_dh_1, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PIRSFiPIRSF000168 Acyl-CoA_oxidase, 1 hit
SUPFAMiSSF47203 SSF47203, 2 hits
SSF56645 SSF56645, 1 hit

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9DBS4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTGWSGLFIE VPLYRLASKV CCHLRGPQGF LQRACQGVCC LPRDSRAAGI
60 70 80 90 100
MEEKRKSFIS QILILGEVLC MVDVSMSIKC GILFLLFGGA ISNLGSPEHV
110 120 130 140 150
TKWFWPLKEQ KYTGMFAMTE RGHGSNVRGI QTEATFDLDN QEFVIDMPCE
160 170 180 190 200
NAHKMYIGNA MHGNYAAVFA QLIIEGKSQG PHCFIVPIRD ENGNLYPGVT
210 220 230 240 250
AIDMMHKEGM NGVDNGILIF DKVRIPRENL LDKFGSVTPD GQYHSPIQSK
260 270 280 290 300
NARFNAILAT LTPSRLAVTF QALGAMKLGL MIAIRYSHSR RQFGPKDKEE
310 320 330 340 350
VKIIEHQMQA LRLMSHLATA LAVTFTSRHA DDILDEDIFQ GRALTNSRSL
360 370 380 390 400
QALMAGLKAY STWETVSCLQ DCRECTGGMG YMMETRISDL KCDTDVFVTF
410 420 430 440 450
EGDNVVMLQV VARELLAQYS KQHKKNLLLG VIQNWTATAG DKLRTSFLAF
460 470 480 490 500
NTDTVGCLAF LLKAVNFRER VLQRSLVSRI YYKVVTKKGD FFSAWNSCMH
510 520 530 540 550
HVTSLSLAHI HRVALEQFTT AVRQCPNRED QALLMKFCLL YGTKLVFQER
560 570 580 590 600
GWYLEHKYLT PKASMLIRAQ LLNLCESVKD DALKVISAFN IPHITIRAPK
610 620 630
TGIPNPGAAE AAYPAPMQPL VRDAARAQLA KL
Length:632
Mass (Da):70,706
Last modified:June 1, 2001 - v1
Checksum:i4BA075171EFE56E1
GO
Isoform 2 (identifier: Q9DBS4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-280: Missing.

Show »
Length:352
Mass (Da):39,777
Checksum:i0D1617A2E88D37A5
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0282401 – 280Missing in isoform 2. 1 PublicationAdd BLAST280

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004775 mRNA Translation: BAB23553.1
AL805950, AL844481 Genomic DNA Translation: CAM14740.1
AL805950, AL844481 Genomic DNA Translation: CAM14741.1
AL844481, AL805950 Genomic DNA Translation: CAM24669.1
AL844481, AL805950 Genomic DNA Translation: CAM24670.1
BC048717 mRNA Translation: AAH48717.1
CCDSiCCDS16711.1 [Q9DBS4-1]
RefSeqiNP_083041.1, NM_028765.3 [Q9DBS4-1]
XP_011238110.1, XM_011239808.1 [Q9DBS4-2]
UniGeneiMm.244835

Genome annotation databases

EnsembliENSMUST00000028859; ENSMUSP00000028859; ENSMUSG00000027380 [Q9DBS4-1]
ENSMUST00000110344; ENSMUSP00000105973; ENSMUSG00000027380 [Q9DBS4-2]
GeneIDi74121
KEGGimmu:74121
UCSCiuc008mgg.2 mouse [Q9DBS4-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiACOXL_MOUSE
AccessioniPrimary (citable) accession number: Q9DBS4
Secondary accession number(s): Q80ZM1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health