Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 132 (16 Oct 2019)
Sequence version 2 (01 Mar 2003)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Amyloid-beta A4 precursor protein-binding family B member 2

Gene

Apbb2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May modulate the internalization of amyloid-beta precursor protein.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Amyloid-beta A4 precursor protein-binding family B member 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Apbb2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:108405 Apbb2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000760531 – 760Amyloid-beta A4 precursor protein-binding family B member 2Add BLAST760

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei123PhosphoserineBy similarity1
Modified residuei160PhosphoserineCombined sources1
Modified residuei334PhosphoserineCombined sources1
Modified residuei409PhosphoserineCombined sources1
Modified residuei412PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9DBR4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9DBR4

PRoteomics IDEntifications database

More...
PRIDEi
Q9DBR4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9DBR4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9DBR4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000029207 Expressed in 293 organ(s), highest expression level in cardiac ventricle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9DBR4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9DBR4 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the intracellular domain of the amyloid-beta precursor protein.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
198142, 4 interactors

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
Q9DBR4

Protein interaction database and analysis system

More...
IntActi
Q9DBR4, 1 interactor

Molecular INTeraction database

More...
MINTi
Q9DBR4

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000125211

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1760
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9DBR4

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9DBR4

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini290 – 322WWPROSITE-ProRule annotationAdd BLAST33
Domaini413 – 580PID 1PROSITE-ProRule annotationAdd BLAST168
Domaini586 – 738PID 2PROSITE-ProRule annotationAdd BLAST153

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEKA Eukaryota
ENOG410YEVS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000000002

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000033983

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9DBR4

KEGG Orthology (KO)

More...
KOi
K04530

Identification of Orthologs from Complete Genome Data

More...
OMAi
IWSDQSF

Database of Orthologous Groups

More...
OrthoDBi
437627at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9DBR4

TreeFam database of animal gene trees

More...
TreeFami
TF314331

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00201 WW, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039576 Fe65
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
IPR001202 WW_dom
IPR036020 WW_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14058 PTHR14058, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00640 PID, 2 hits
PF00397 WW, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00462 PTB, 2 hits
SM00456 WW, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51045 SSF51045, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01179 PID, 2 hits
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 11 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9DBR4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSEVLPADSG VGTLAVFMAS SGSTDIANRN SPATPPNTLN LRSSHNELLN
60 70 80 90 100
AEIKHSDAKN STPPKCRKKY ALTNIQAAMG LSDPAVQPLL GNGSANIKLV
110 120 130 140 150
KNGENQLRKA AEQGQQDPNK NLSPAAVINL TSEKLEVKDP HPQESSGCEI
160 170 180 190 200
LPSQPRRTKS FLNYYADLET SARELGQNLG PCQGVGEEKA QPGPGQAPVV
210 220 230 240 250
IGNGDLLPQK PNKPQSSPED GQVATVSSSP ETKKDHPKTG AKTDCALHRI
260 270 280 290 300
QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVN
310 320 330 340 350
DIAGTYYWHI PTGTTQWERP VSIPADLHGS RKGSLSSVTP SPTPENEKQP
360 370 380 390 400
WSDFAVLNGG KINSDIWKDL HAATVNPDPS LKEFEGATLR YASLKLRNAP
410 420 430 440 450
HGDDDDSCSI NSDPEAKCFA VRSLGWVEMA EEDLAPGKSS VAVNNCIRQL
460 470 480 490 500
SYCKNDIRDT VGIWGEGKDM YLSLENDMLS LVDPMDRSVL HSQPIVNIRV
510 520 530 540 550
WGVGRDNGRE RDFAYVARDK DTRILKCHVF RCDTPAKAIA TSLHEICSKI
560 570 580 590 600
MAERKNAKAL ACSSLQERTN MSLDVPLQVD FPTPKTELVQ KFRVQYLGML
610 620 630 640 650
PVDRPVGMDT LNSAIENLMT SSSKEDWPSV NMNVADATVT VISEKNEEEV
660 670 680 690 700
LVECRVRFLS FMGVGKDVHT FAFIMDTGNQ RFECHVFWCE PNAANVSEAV
710 720 730 740 750
QAACMLRYQK CLVARPPSQK VRPPPPPADS VTRRVTTNVK RGVLSLIDTL
760
KQKRPVTETP
Length:760
Mass (Da):83,201
Last modified:March 1, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9E66E34489F4D736
GO
Isoform 2 (identifier: Q9DBR4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     348-368: Missing.

Show »
Length:739
Mass (Da):80,815
Checksum:i5821BB835A62868C
GO
Isoform 3 (identifier: Q9DBR4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     348-368: Missing.
     509-510: Missing.

Show »
Length:737
Mass (Da):80,530
Checksum:i2A8C34E8176E223C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PWH3E9PWH3_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
738Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q3TDW6Q3TDW6_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
736Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q3TIZ5Q3TIZ5_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
758Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QPX0E9QPX0_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
760Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6V8Y6F6V8Y6_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
510Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CYJ4E0CYJ4_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CYY8E0CYY8_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
93Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CZA9E0CZA9_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
102Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CZ85E0CZ85_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CYB2E0CYB2_MOUSE
Amyloid-beta A4 precursor protein-b...
Apbb2
12Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_011661348 – 368Missing in isoform 2 and isoform 3. 1 PublicationAdd BLAST21
Alternative sequenceiVSP_011662509 – 510Missing in isoform 3. 1 Publication2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK004792 mRNA Translation: BAB23568.2
BC076587 mRNA Translation: AAH76587.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS51510.1 [Q9DBR4-1]
CCDS57344.1 [Q9DBR4-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001188343.1, NM_001201414.1
NP_001188344.1, NM_001201415.1 [Q9DBR4-3]
NP_033816.1, NM_009686.2 [Q9DBR4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000159786; ENSMUSP00000125211; ENSMUSG00000029207 [Q9DBR4-3]
ENSMUST00000162349; ENSMUSP00000123752; ENSMUSG00000029207 [Q9DBR4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
11787

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:11787

UCSC genome browser

More...
UCSCi
uc008xpb.2 mouse [Q9DBR4-3]
uc033ijy.1 mouse [Q9DBR4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004792 mRNA Translation: BAB23568.2
BC076587 mRNA Translation: AAH76587.1
CCDSiCCDS51510.1 [Q9DBR4-1]
CCDS57344.1 [Q9DBR4-3]
RefSeqiNP_001188343.1, NM_001201414.1
NP_001188344.1, NM_001201415.1 [Q9DBR4-3]
NP_033816.1, NM_009686.2 [Q9DBR4-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WGUNMR-A582-704[»]
2ROZNMR-B582-704[»]
2YSZNMR-A582-704[»]
2YT0NMR-A582-704[»]
2YT1NMR-A582-704[»]
SMRiQ9DBR4
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi198142, 4 interactors
ELMiQ9DBR4
IntActiQ9DBR4, 1 interactor
MINTiQ9DBR4
STRINGi10090.ENSMUSP00000125211

PTM databases

iPTMnetiQ9DBR4
PhosphoSitePlusiQ9DBR4

Proteomic databases

jPOSTiQ9DBR4
PaxDbiQ9DBR4
PRIDEiQ9DBR4

Genome annotation databases

EnsembliENSMUST00000159786; ENSMUSP00000125211; ENSMUSG00000029207 [Q9DBR4-3]
ENSMUST00000162349; ENSMUSP00000123752; ENSMUSG00000029207 [Q9DBR4-1]
GeneIDi11787
KEGGimmu:11787
UCSCiuc008xpb.2 mouse [Q9DBR4-3]
uc033ijy.1 mouse [Q9DBR4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
323
MGIiMGI:108405 Apbb2

Phylogenomic databases

eggNOGiENOG410IEKA Eukaryota
ENOG410YEVS LUCA
GeneTreeiENSGT00390000000002
HOGENOMiHOG000033983
InParanoidiQ9DBR4
KOiK04530
OMAiIWSDQSF
OrthoDBi437627at2759
PhylomeDBiQ9DBR4
TreeFamiTF314331

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Apbb2 mouse
EvolutionaryTraceiQ9DBR4

Protein Ontology

More...
PROi
PR:Q9DBR4

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000029207 Expressed in 293 organ(s), highest expression level in cardiac ventricle
ExpressionAtlasiQ9DBR4 baseline and differential
GenevisibleiQ9DBR4 MM

Family and domain databases

CDDicd00201 WW, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR039576 Fe65
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
IPR001202 WW_dom
IPR036020 WW_dom_sf
PANTHERiPTHR14058 PTHR14058, 1 hit
PfamiView protein in Pfam
PF00640 PID, 2 hits
PF00397 WW, 1 hit
SMARTiView protein in SMART
SM00462 PTB, 2 hits
SM00456 WW, 1 hit
SUPFAMiSSF51045 SSF51045, 1 hit
PROSITEiView protein in PROSITE
PS01179 PID, 2 hits
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAPBB2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9DBR4
Secondary accession number(s): Q6DFX8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: March 1, 2003
Last modified: October 16, 2019
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again