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Entry version 137 (02 Jun 2021)
Sequence version 3 (27 Jul 2011)
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Protein

GON-4-like protein

Gene

Gon4l

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1 (PubMed:21454521).

Required for B cell lymphopoiesis (PubMed:20530203).

2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GON-4-like protein
Alternative name(s):
GON-4 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gon4l
Synonyms:Gon4, Kiaa1606
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1917579, Gon4l

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001971101 – 2260GON-4-like proteinAdd BLAST2260

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei347PhosphoserineBy similarity1
Modified residuei784PhosphoserineCombined sources1
Modified residuei1925PhosphoserineBy similarity1
Modified residuei1998PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9DB00

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9DB00

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9DB00

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9DB00

PRoteomics IDEntifications database

More...
PRIDEi
Q9DB00

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
271251

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9DB00

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9DB00

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in thymus. Specifically expressed in B cells and their precursors (at protein level). Also detected in brain, heart, spleen and bone marrow.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Found in a complex with YY1, SIN3A and HDAC1.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
217912, 4 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q9DB00

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000088461

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9DB00, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12260
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9DB00

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q9DB00

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1648 – 1720PAH 1PROSITE-ProRule annotationAdd BLAST73
Domaini1730 – 1801PAH 2PROSITE-ProRule annotationAdd BLAST72
Domaini2167 – 2220Myb-likePROSITE-ProRule annotationAdd BLAST54

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 67DisorderedSequence analysisAdd BLAST67
Regioni137 – 212DisorderedSequence analysisAdd BLAST76
Regioni228 – 264DisorderedSequence analysisAdd BLAST37
Regioni367 – 434DisorderedSequence analysisAdd BLAST68
Regioni546 – 576DisorderedSequence analysisAdd BLAST31
Regioni610 – 1364Required for interaction with YY1, SIN3A AND HDAC1, and transcriptional repression activity1 PublicationAdd BLAST755
Regioni613 – 634DisorderedSequence analysisAdd BLAST22
Regioni946 – 976DisorderedSequence analysisAdd BLAST31
Regioni1367 – 1625DisorderedSequence analysisAdd BLAST259
Regioni1835 – 1935DisorderedSequence analysisAdd BLAST101
Regioni1949 – 1974DisorderedSequence analysisAdd BLAST26
Regioni2026 – 2088DisorderedSequence analysisAdd BLAST63
Regioni2134 – 2162DisorderedSequence analysisAdd BLAST29
Regioni2227 – 2260DisorderedSequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi39 – 59Polar residuesSequence analysisAdd BLAST21
Compositional biasi142 – 174Basic and acidic residuesSequence analysisAdd BLAST33
Compositional biasi179 – 194Polar residuesSequence analysisAdd BLAST16
Compositional biasi367 – 392Acidic residuesSequence analysisAdd BLAST26
Compositional biasi546 – 572Acidic residuesSequence analysisAdd BLAST27
Compositional biasi946 – 967Polar residuesSequence analysisAdd BLAST22
Compositional biasi1368 – 1383Basic and acidic residuesSequence analysisAdd BLAST16
Compositional biasi1384 – 1407Polar residuesSequence analysisAdd BLAST24
Compositional biasi1419 – 1444Polar residuesSequence analysisAdd BLAST26
Compositional biasi1477 – 1502Acidic residuesSequence analysisAdd BLAST26
Compositional biasi1536 – 1560Acidic residuesSequence analysisAdd BLAST25
Compositional biasi1837 – 1870Basic and acidic residuesSequence analysisAdd BLAST34
Compositional biasi1896 – 1910Basic and acidic residuesSequence analysisAdd BLAST15

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QT2W, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q9DB00

Database of Orthologous Groups

More...
OrthoDBi
49443at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1160.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033277, GON-4-like
IPR009057, Homeobox-like_sf
IPR017877, Myb-like_dom
IPR003822, PAH
IPR036600, PAH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR16088:SF11, PTHR16088:SF11, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02671, PAH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46689, SSF46689, 1 hit
SSF47762, SSF47762, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50090, MYB_LIKE, 1 hit
PS51477, PAH, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q9DB00-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLPCKKRRLS VTESSQQQDD QEGDDLDLEA AVKPDTDQLP DSASESLSWG
60 70 80 90 100
QSQDSAVCPE GLSMQDGDDQ LRAEGLSLNS KMLAQHVNLA VLEAVDVAVS
110 120 130 140 150
QEIPLPSLES SHSLPVHVDK GRLQVSASKK GKRVVFTPGQ VTREDRGDHP
160 170 180 190 200
VPEEPPSGEP AEEAKTEGGE LELRSDGEVP LLSSSSQSAK PGAQPRKSVQ
210 220 230 240 250
PDGSAFPQDK PLGPLVRQAE EEMEDGGLFI PTEEQDSEES DKKKKTKKGT
260 270 280 290 300
KRKRDGKGPE QGTMVYDPKL DDMLDRTLED GAKQHNLTAV NVRNILHEVI
310 320 330 340 350
TNEHVVAMMK AAISETEDMP LFEPKMTRSK LKEVVEKGVV IPTWNISPIK
360 370 380 390 400
KASEIKQPPQ FVDIHLEEDD SSDEEYSPDE EEEDETAEES LLESDVESTA
410 420 430 440 450
SSPRGVKRSR LRLSSEVAET DEESGMLSEV EKAATPALRH ISAEVVPMGP
460 470 480 490 500
PPPPKPKQSR DSVFMEKLDA VDEELASSPV CMDSFQPMED SLIAFRTRSK
510 520 530 540 550
MPLKDVPLGQ LEAELQAPDI TPDMYDPNTA DDEDWKQWLG GLINDDVENE
560 570 580 590 600
DEADDDDDPE YNFLEDLDEP DTEDFRTDRA VRITKKEVNG LMEELFETVQ
610 620 630 640 650
SVVPSKFQDE MGFSNMEDDG PEEEERATES RPSFNTPQAL RFEEPLANLL
660 670 680 690 700
NERHRTVKEL LEQLKMKKPS VRQQPEVEKL KPQEEAAHQT LVLDPAQRSR
710 720 730 740 750
LQQQMQQHVQ LLTQIYLLTT SNPNLSSEAS TTRIFLKELG TFAENSIALH
760 770 780 790 800
QQFNPRFQTL FQPCNWMGAM RLIEDFTQVS IDCSPHKTAK KTASEFPCLP
810 820 830 840 850
KQVAWILATN KVFMYPELLP ICSLKANNPR DKTIFTKAED NLLALGLKHF
860 870 880 890 900
EGTEFPKPLI SKYLVTCKTA HQLTVRIKNL NLNRAPNNVI KFYKKTKQLP
910 920 930 940 950
VLVRCCEEIQ PHQWKPPFEK EEHRLPFWLK ASLQSIQDEL RNISEGATEG
960 970 980 990 1000
GSVTTATESS TDQHLQKASP ALGDEPQYPL LLPKGVVLKL KPGSKRFSRK
1010 1020 1030 1040 1050
AWRQKRPLVQ KPLLIQPSPS VQPVFNPGKM ATWPTQSEVP PSNTVVQIPH
1060 1070 1080 1090 1100
LIQPAAVLQT LPGFPSVGVR GEDGFESPTA LPAMPCGSEA RTTFPLSETQ
1110 1120 1130 1140 1150
SAPPSCSAPK LMLPSLAPSK FRKPYVRRKP TRRKGAKVSP CVKPAPIIHP
1160 1170 1180 1190 1200
TPVIFTVPAT TVKVVSIGGG CNMIQPVSAA VAPSPQTIPI TTLLVNPTTF
1210 1220 1230 1240 1250
PCSLNQPLVA SSISPLIVSS NPLTLPVTSI PEDKAQVKLD VAEGKNAPQN
1260 1270 1280 1290 1300
PESKLKPQEL TPLCTTVFSK EEPKSWHSSA DTGSQEAFSE SSACSWAVVK
1310 1320 1330 1340 1350
TESQEGSSEK SACGWTVVKT EDGGHAVEPL PQNLQDSLSS SSKDLLNMVK
1360 1370 1380 1390 1400
MEAQDCMVEI SSNFPKQDIG EEVKEECSME LDSESPQEKP SSASEMSKQT
1410 1420 1430 1440 1450
VLQREDMQAA KSPSVPQDAA AEGRTSSHAS RGLPKSTLSS MGQGGGLSGP
1460 1470 1480 1490 1500
PGKLEDSANA DGQSVGTPAG PDTGGEKDGP EEEEEEDFDD LTQDEEDELS
1510 1520 1530 1540 1550
SASEESVLSV PELQETMEKL TWLASERRMS QEGESEEENS QEENSEPEEE
1560 1570 1580 1590 1600
EEEEAEGMET LQKEDEVNDE AVGDAAKKPP STLASPQTAP EIETSIAPAG
1610 1620 1630 1640 1650
ESIKAAGKGR SSHRARNKRG SRARASKDTS KLLLLYDEDI LDRDPLREQK
1660 1670 1680 1690 1700
DLAFAQAYLT RVREALQHTP GKYEDFLQII YEFESSTQMH SAVDLFKSLQ
1710 1720 1730 1740 1750
TLLQDWPQLL KDFAAFLLPE QALSCGLFEE QQAFEKSRKF LRQLEICFAE
1760 1770 1780 1790 1800
NPSHHQKIIK VLQGCADCLP QDIAELKTQM WQLLRGHDHL QDEFSIFFDH
1810 1820 1830 1840 1850
LRPAASRMGD FEEINWTEEK EYEFDGFEEV ILPDVEEDEE PAKVSTASKS
1860 1870 1880 1890 1900
KRRKEIGVQH QDKDTEWPEA AKDCSCSCHE GGPESKLKKS KRRNCHCSSK
1910 1920 1930 1940 1950
VCDSKPYKSK EPPELVGSGP LHEASTVPGS KEAGQGKDML EEEILEEQEN
1960 1970 1980 1990 2000
MEVTQSKTAR TTRKGEAPAP GSTIGSTLLC PAEVTPMELL LEGPALCSAE
2010 2020 2030 2040 2050
TPRLPPQTGA VVCSVRRNQA GPEVVSCLST SSLPPEEGED QRAAANSETI
2060 2070 2080 2090 2100
APHREASETE RLPETVEHSA PLPSPVSTRT RDTGRRHICG KAGSQSWLIE
2110 2120 2130 2140 2150
SRAEAEAAHV AAPICEKSSG ARASEAAPKT AREVLAEDSG TQGMGPEGAL
2160 2170 2180 2190 2200
PKASEATVCA NNSKVSSTGE KVVLWTREAD RVILTMCQEQ GAQPHTFSVI
2210 2220 2230 2240 2250
SQQLGNKTPV EVSHRFRELM QLFHTACEAS SEDEDDATST SNADQLSDHG
2260
DLLSEEELDE
Length:2,260
Mass (Da):248,742
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB0F605666D642C6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K4DI71K4DI71_MOUSE
GON-4-like protein
Gon4l
2,243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q507E9Q507_MOUSE
GON-4-like protein
Gon4l
2,242Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RM47A0A1D5RM47_MOUSE
GON-4-like protein
Gon4l
502Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH16616 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB23992 differs from that shown. Chimeric cDNA.Curated
The sequence BAC65813 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti259P → L in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti734I → V in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1080A → S in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1341S → P in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1354Q → E in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1364F → L in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1392S → R in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1407M → T in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1438L → P in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti1458A → V in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti2069S → P in BAC65813 (PubMed:12693553).Curated1
Sequence conflicti2069S → P in AAH16616 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC127377 Genomic DNA No translation available.
AK005385 mRNA Translation: BAB23992.1 Different termination.
AK122531 mRNA Translation: BAC65813.1 Different initiation.
BC016616 mRNA Translation: AAH16616.1 Different initiation.

NCBI Reference Sequences

More...
RefSeqi
XP_017175282.1, XM_017319793.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
76022

UCSC genome browser

More...
UCSCi
uc008pxb.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127377 Genomic DNA No translation available.
AK005385 mRNA Translation: BAB23992.1 Different termination.
AK122531 mRNA Translation: BAC65813.1 Different initiation.
BC016616 mRNA Translation: AAH16616.1 Different initiation.
RefSeqiXP_017175282.1, XM_017319793.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1UG2NMR-A2148-2228[»]
SMRiQ9DB00
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi217912, 4 interactors
CORUMiQ9DB00
STRINGi10090.ENSMUSP00000088461

PTM databases

iPTMnetiQ9DB00
PhosphoSitePlusiQ9DB00

Proteomic databases

EPDiQ9DB00
jPOSTiQ9DB00
MaxQBiQ9DB00
PaxDbiQ9DB00
PRIDEiQ9DB00
ProteomicsDBi271251

Genome annotation databases

GeneIDi76022
UCSCiuc008pxb.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
54856
MGIiMGI:1917579, Gon4l

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiENOG502QT2W, Eukaryota
InParanoidiQ9DB00
OrthoDBi49443at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
76022, 8 hits in 53 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Gon4l, mouse
EvolutionaryTraceiQ9DB00

Protein Ontology

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PROi
PR:Q9DB00
RNActiQ9DB00, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Family and domain databases

Gene3Di1.20.1160.11, 1 hit
InterProiView protein in InterPro
IPR033277, GON-4-like
IPR009057, Homeobox-like_sf
IPR017877, Myb-like_dom
IPR003822, PAH
IPR036600, PAH_sf
PANTHERiPTHR16088:SF11, PTHR16088:SF11, 2 hits
PfamiView protein in Pfam
PF02671, PAH, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
SSF47762, SSF47762, 2 hits
PROSITEiView protein in PROSITE
PS50090, MYB_LIKE, 1 hit
PS51477, PAH, 2 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGON4L_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9DB00
Secondary accession number(s): E9Q5N3, Q80TB4, Q91YI9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 27, 2011
Last modified: June 2, 2021
This is version 137 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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