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Protein

Tektin-1

Gene

Tekt1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).By similarity

GO - Biological processi

  • cilium assembly Source: GO_Central
  • cilium movement involved in cell motility Source: GO_Central
  • flagellated sperm motility Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Tektin-1
Gene namesi
Name:Tekt1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1333819 Tekt1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001845631 – 418Tektin-1Add BLAST418

Proteomic databases

MaxQBiQ9DAJ2
PaxDbiQ9DAJ2
PRIDEiQ9DAJ2

2D gel databases

REPRODUCTION-2DPAGEiQ9DAJ2

PTM databases

PhosphoSitePlusiQ9DAJ2

Expressioni

Gene expression databases

BgeeiENSMUSG00000020799 Expressed in 151 organ(s), highest expression level in testis
CleanExiMM_TEKT1
ExpressionAtlasiQ9DAJ2 baseline and differential
GenevisibleiQ9DAJ2 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021155

Structurei

3D structure databases

SMRiQ9DAJ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili20 – 107Sequence analysisAdd BLAST88
Coiled coili134 – 177Sequence analysisAdd BLAST44
Coiled coili266 – 308Sequence analysisAdd BLAST43
Coiled coili332 – 383Sequence analysisAdd BLAST52

Sequence similaritiesi

Belongs to the tektin family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG2685 Eukaryota
ENOG410XSCN LUCA
GeneTreeiENSGT00390000016344
HOGENOMiHOG000246943
HOVERGENiHBG056503
InParanoidiQ9DAJ2
KOiK18628
OMAiANKSQYH
OrthoDBiEOG091G0AJL
PhylomeDBiQ9DAJ2
TreeFamiTF320754

Family and domain databases

InterProiView protein in InterPro
IPR000435 Tektin
PANTHERiPTHR19960 PTHR19960, 1 hit
PRINTSiPR00511 TEKTIN

Sequencei

Sequence statusi: Complete.

Q9DAJ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKLLQSPPR FLPEEWYIAN KSQYHRAEAQ RSQSERLVAE SQRLVEEIEK
60 70 80 90 100
TTRKSQSDVN KKLEQRLEEV RFWKKELDDK LEQLVNQTDD LLTYKTRLER
110 120 130 140 150
SLESYKEPLH ITEKCLEYRE KRVGIDLVHD VVEQELQKEA DIIHGVMNLL
160 170 180 190 200
IRTLEESTEQ IRLNRSAKYN LEKDLRDKFT AITIDDVCFS LNNNSPNINF
210 220 230 240 250
SEKVVRIEPN SVSLEDWLDF SNANVEKADK QLNNSTALKT LVDQILSQTA
260 270 280 290 300
NDLRRQCEVV DEAFINGLKE TKDARNKLAD HLAKVMEEIA SQEKNIMALE
310 320 330 340 350
NAITQQEGPA KVAHTRLETR THRPNVELCR DIAQYRLIKE IQEINHNVAR
360 370 380 390 400
LKETLAQAQT QLKALYRRQL ALQEEIQVKE NTIYIDQVLC MEMRKSIPPR
410
DGDDHGAWEG GIRAEAIC
Length:418
Mass (Da):48,641
Last modified:June 1, 2001 - v1
Checksum:i1EA101615FEB527B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005801 mRNA Translation: BAB24244.1
CCDSiCCDS36215.1
RefSeqiNP_001268935.1, NM_001282006.1
NP_001268936.1, NM_001282007.1
NP_035699.2, NM_011569.3
UniGeneiMm.42257

Genome annotation databases

EnsembliENSMUST00000021155; ENSMUSP00000021155; ENSMUSG00000020799
ENSMUST00000108502; ENSMUSP00000104142; ENSMUSG00000020799
ENSMUST00000108503; ENSMUSP00000104143; ENSMUSG00000020799
GeneIDi21689
KEGGimmu:21689
UCSCiuc007jyt.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005801 mRNA Translation: BAB24244.1
CCDSiCCDS36215.1
RefSeqiNP_001268935.1, NM_001282006.1
NP_001268936.1, NM_001282007.1
NP_035699.2, NM_011569.3
UniGeneiMm.42257

3D structure databases

SMRiQ9DAJ2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000021155

PTM databases

PhosphoSitePlusiQ9DAJ2

2D gel databases

REPRODUCTION-2DPAGEiQ9DAJ2

Proteomic databases

MaxQBiQ9DAJ2
PaxDbiQ9DAJ2
PRIDEiQ9DAJ2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000021155; ENSMUSP00000021155; ENSMUSG00000020799
ENSMUST00000108502; ENSMUSP00000104142; ENSMUSG00000020799
ENSMUST00000108503; ENSMUSP00000104143; ENSMUSG00000020799
GeneIDi21689
KEGGimmu:21689
UCSCiuc007jyt.2 mouse

Organism-specific databases

CTDi83659
MGIiMGI:1333819 Tekt1

Phylogenomic databases

eggNOGiKOG2685 Eukaryota
ENOG410XSCN LUCA
GeneTreeiENSGT00390000016344
HOGENOMiHOG000246943
HOVERGENiHBG056503
InParanoidiQ9DAJ2
KOiK18628
OMAiANKSQYH
OrthoDBiEOG091G0AJL
PhylomeDBiQ9DAJ2
TreeFamiTF320754

Miscellaneous databases

PROiPR:Q9DAJ2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020799 Expressed in 151 organ(s), highest expression level in testis
CleanExiMM_TEKT1
ExpressionAtlasiQ9DAJ2 baseline and differential
GenevisibleiQ9DAJ2 MM

Family and domain databases

InterProiView protein in InterPro
IPR000435 Tektin
PANTHERiPTHR19960 PTHR19960, 1 hit
PRINTSiPR00511 TEKTIN
ProtoNetiSearch...

Entry informationi

Entry nameiTEKT1_MOUSE
AccessioniPrimary (citable) accession number: Q9DAJ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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