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Protein

Protein DDI1 homolog 1

Gene

Ddi1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable aspartic protease.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei266Curated1

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl protease, Hydrolase, Protease

Protein family/group databases

MEROPSiA28.A01

Names & Taxonomyi

Protein namesi
Recommended name:
Protein DDI1 homolog 1 (EC:3.4.23.-By similarity)
Gene namesi
Name:Ddi1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1919079 Ddi1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002870881 – 408Protein DDI1 homolog 1Add BLAST408

Proteomic databases

MaxQBiQ9DAF3
PaxDbiQ9DAF3
PeptideAtlasiQ9DAF3
PRIDEiQ9DAF3

PTM databases

iPTMnetiQ9DAF3
PhosphoSitePlusiQ9DAF3

Expressioni

Gene expression databases

BgeeiENSMUSG00000047619 Expressed in 11 organ(s), highest expression level in testis
GenevisibleiQ9DAF3 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000053223

Structurei

Secondary structure

1408
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ9DAF3
SMRiQ9DAF3
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9DAF3

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 81Ubiquitin-likePROSITE-ProRule annotationAdd BLAST81

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi111 – 122His-richPROSITE-ProRule annotationAdd BLAST12

Sequence similaritiesi

Belongs to the DDI1 family.Curated

Phylogenomic databases

eggNOGiKOG0012 Eukaryota
ENOG410XPA0 LUCA
GeneTreeiENSGT00510000047125
HOGENOMiHOG000234736
HOVERGENiHBG058638
InParanoidiQ9DAF3
KOiK11885
OMAiITVYCVR
OrthoDBiEOG091G0CIP
PhylomeDBiQ9DAF3
TreeFamiTF333421

Family and domain databases

CDDicd01796 DDI1_N, 1 hit
cd05479 RP_DDI, 1 hit
Gene3Di2.40.70.10, 1 hit
InterProiView protein in InterPro
IPR033322 DDI1
IPR033882 DDI1_N
IPR019103 Peptidase_aspartic_DDI1-type
IPR021109 Peptidase_aspartic_dom_sf
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PANTHERiPTHR12917 PTHR12917, 1 hit
PfamiView protein in Pfam
PF09668 Asp_protease, 1 hit
PF00240 ubiquitin, 1 hit
SUPFAMiSSF50630 SSF50630, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9DAF3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLITVYCVRR DLTEVTFSLQ VNPDFELSNF RVLCELESGV PAEEAQIVYM
60 70 80 90 100
EQLLTDDHCS LGSYGLKDGD MVVLLQKDNV GLRTPGRTPN HPRADFTGSG
110 120 130 140 150
SAVPGTSSSR HPHQHQHHYH HHQRIPSTQQ AHGLASGENM TFAQELDSPA
160 170 180 190 200
LIRSMLLSNP HDLSLLKERN PALAEALLSG NLETFSQVLM EQQRERTLRE
210 220 230 240 250
QEMFRLYSTN PFDQETQARI EEEIRQQNIE ENMNIAMEEA PESFGQVAML
260 270 280 290 300
YINCKVNGHP LKAFVDSGAQ MTIMSQACAE RCNIMRLVDR RWGGVAKGVG
310 320 330 340 350
TQRIMGRVHL AQIQIEGDFL QCSFSILEEQ PMDILLGLDM LRRHQCSIDL
360 370 380 390 400
KKNVLVIGTT GSQTHFLPEG ELPLCAKLLS GTVQEESSDR EVGGTIKHPV

KGPGRKKH
Length:408
Mass (Da):45,713
Last modified:June 1, 2001 - v1
Checksum:i56A496D962DC878C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005882 mRNA Translation: BAB24297.1
CCDSiCCDS40527.1
RefSeqiNP_082218.1, NM_027942.1
UniGeneiMm.141452

Genome annotation databases

EnsembliENSMUST00000051706; ENSMUSP00000053223; ENSMUSG00000047619
GeneIDi71829
KEGGimmu:71829
UCSCiuc009oca.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005882 mRNA Translation: BAB24297.1
CCDSiCCDS40527.1
RefSeqiNP_082218.1, NM_027942.1
UniGeneiMm.141452

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V5ONMR-A1-89[»]
ProteinModelPortaliQ9DAF3
SMRiQ9DAF3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000053223

Protein family/group databases

MEROPSiA28.A01

PTM databases

iPTMnetiQ9DAF3
PhosphoSitePlusiQ9DAF3

Proteomic databases

MaxQBiQ9DAF3
PaxDbiQ9DAF3
PeptideAtlasiQ9DAF3
PRIDEiQ9DAF3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000051706; ENSMUSP00000053223; ENSMUSG00000047619
GeneIDi71829
KEGGimmu:71829
UCSCiuc009oca.1 mouse

Organism-specific databases

CTDi414301
MGIiMGI:1919079 Ddi1

Phylogenomic databases

eggNOGiKOG0012 Eukaryota
ENOG410XPA0 LUCA
GeneTreeiENSGT00510000047125
HOGENOMiHOG000234736
HOVERGENiHBG058638
InParanoidiQ9DAF3
KOiK11885
OMAiITVYCVR
OrthoDBiEOG091G0CIP
PhylomeDBiQ9DAF3
TreeFamiTF333421

Miscellaneous databases

EvolutionaryTraceiQ9DAF3
PROiPR:Q9DAF3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000047619 Expressed in 11 organ(s), highest expression level in testis
GenevisibleiQ9DAF3 MM

Family and domain databases

CDDicd01796 DDI1_N, 1 hit
cd05479 RP_DDI, 1 hit
Gene3Di2.40.70.10, 1 hit
InterProiView protein in InterPro
IPR033322 DDI1
IPR033882 DDI1_N
IPR019103 Peptidase_aspartic_DDI1-type
IPR021109 Peptidase_aspartic_dom_sf
IPR029071 Ubiquitin-like_domsf
IPR000626 Ubiquitin_dom
PANTHERiPTHR12917 PTHR12917, 1 hit
PfamiView protein in Pfam
PF09668 Asp_protease, 1 hit
PF00240 ubiquitin, 1 hit
SUPFAMiSSF50630 SSF50630, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDDI1_MOUSE
AccessioniPrimary (citable) accession number: Q9DAF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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