We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q9D9T6 (SPTA3_MOUSE)
Protein
Spermatogenesis-associated protein 3
Gene
Spata3
Organism
Mus musculus (Mouse)
Status
Functioni
Names & Taxonomyi
Protein namesi | Recommended name: Spermatogenesis-associated protein 3Alternative name(s): Testis and spermatogenesis cell-related protein 1 Short name: mTSARG1 Testis spermatocyte apoptosis-related protein 1 |
Gene namesi | Name:Spata3 Synonyms:Tsarg1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1917310, Spata3 |
VEuPathDBi | HostDB:ENSMUSG00000026226 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000072175 | 1 – 193 | Spermatogenesis-associated protein 3Add BLAST | 193 |
Proteomic databases
PaxDbi | Q9D9T6 |
ProteomicsDBi | 261637 [Q9D9T6-1] 261638 [Q9D9T6-2] 261639 [Q9D9T6-3] |
PTM databases
iPTMneti | Q9D9T6 |
PhosphoSitePlusi | Q9D9T6 |
Expressioni
Tissue specificityi
Strongly expressed in testis. Faintly expressed in epididymis, ovary, spleen, kidney, lung, heart, brain, epididymis, liver and skeletal muscle.1 Publication
Gene expression databases
Bgeei | ENSMUSG00000026226, Expressed in testis and 75 other tissues |
Genevisiblei | Q9D9T6, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 213843, 1 interactor |
STRINGi | 10090.ENSMUSP00000050509 |
Miscellaneous databases
RNActi | Q9D9T6, protein |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 92 | DisorderedSequence analysisAdd BLAST | 92 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 16 – 33 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 34 – 51 | Pro residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 64 – 91 | Pro residuesSequence analysisAdd BLAST | 28 |
Phylogenomic databases
eggNOGi | ENOG502TDUQ, Eukaryota |
GeneTreei | ENSGT00390000003032 |
HOGENOMi | CLU_099077_0_0_1 |
InParanoidi | Q9D9T6 |
OMAi | TFYRKPP |
OrthoDBi | 1608431at2759 |
TreeFami | TF338040 |
Family and domain databases
InterProi | View protein in InterPro IPR026717, SPATA3 |
PANTHERi | PTHR22234, PTHR22234, 1 hit |
Pfami | View protein in Pfam PF15662, SPATA3, 1 hit |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q9D9T6-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MKKVKKKKSD SRRRRNSISP QTSSDSSQQP SSETPPSCPE PASPPSKPQP
60 70 80 90 100
CQESTTPHQV NPEPKPQQHT PQPLPPPEKP ASSPFLVPME PKPILPSRKA
110 120 130 140 150
AVPLTYVAPR SCSCAACPGS SACWHRLGLC HSRIFDVLLP RDWSSMPGRG
160 170 180 190
VPNLLTFYRK PSRKYCAPRN SRASSSRNCC CGSGGLGSCL LHG
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA5HNY3 | A5HNY3_MOUSE | Spata3 variant 4 | Spata3 | 138 | Annotation score: | ||
Q6P8X3 | Q6P8X3_MOUSE | Spermatogenesis associated 3 | Spata3 | 171 | Annotation score: | ||
F6UTK3 | F6UTK3_MOUSE | Spermatogenesis-associated protein ... | Spata3 | 174 | Annotation score: | ||
A0A2I3BR17 | A0A2I3BR17_MOUSE | Spermatogenesis-associated protein ... | Spata3 | 333 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 16 | N → D in BAB24616 (PubMed:16141072).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_008523 | 87 – 89 | VPM → QCL in isoform 4. 1 Publication | 3 | |
Alternative sequenceiVSP_008524 | 90 – 193 | Missing in isoform 4. 1 PublicationAdd BLAST | 104 | |
Alternative sequenceiVSP_008525 | 101 | Missing in isoform 2 and isoform 3. 2 Publications | 1 | |
Alternative sequenceiVSP_008526 | 160 – 171 | KPSRK…APRNS → FRMNGRAKKPWV in isoform 3. 1 PublicationAdd BLAST | 12 | |
Alternative sequenceiVSP_008527 | 172 – 193 | Missing in isoform 3. 1 PublicationAdd BLAST | 22 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF399971 mRNA Translation: AAM90619.1 AK005880 mRNA Translation: BAB24295.1 AK006491 mRNA Translation: BAB24616.1 AK015193 mRNA Translation: BAB29741.1 BC048516 mRNA Translation: AAH48516.1 |
CCDSi | CCDS15116.1 [Q9D9T6-2] CCDS35643.1 [Q9D9T6-1] CCDS48301.1 [Q9D9T6-3] |
RefSeqi | NP_001116204.1, NM_001122732.1 [Q9D9T6-2] NP_081305.1, NM_027029.2 [Q9D9T6-3] NP_081576.2, NM_027300.3 [Q9D9T6-1] NP_082923.1, NM_028647.4 [Q9D9T6-2] |
Genome annotation databases
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF399971 mRNA Translation: AAM90619.1 AK005880 mRNA Translation: BAB24295.1 AK006491 mRNA Translation: BAB24616.1 AK015193 mRNA Translation: BAB29741.1 BC048516 mRNA Translation: AAH48516.1 |
CCDSi | CCDS15116.1 [Q9D9T6-2] CCDS35643.1 [Q9D9T6-1] CCDS48301.1 [Q9D9T6-3] |
RefSeqi | NP_001116204.1, NM_001122732.1 [Q9D9T6-2] NP_081305.1, NM_027029.2 [Q9D9T6-3] NP_081576.2, NM_027300.3 [Q9D9T6-1] NP_082923.1, NM_028647.4 [Q9D9T6-2] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 213843, 1 interactor |
STRINGi | 10090.ENSMUSP00000050509 |
PTM databases
iPTMneti | Q9D9T6 |
PhosphoSitePlusi | Q9D9T6 |
Proteomic databases
PaxDbi | Q9D9T6 |
ProteomicsDBi | 261637 [Q9D9T6-1] 261638 [Q9D9T6-2] 261639 [Q9D9T6-3] |
Protocols and materials databases
Antibodypediai | 11837, 47 antibodies from 21 providers |
Genome annotation databases
Organism-specific databases
CTDi | 130560 |
MGIi | MGI:1917310, Spata3 |
VEuPathDBi | HostDB:ENSMUSG00000026226 |
Phylogenomic databases
eggNOGi | ENOG502TDUQ, Eukaryota |
GeneTreei | ENSGT00390000003032 |
HOGENOMi | CLU_099077_0_0_1 |
InParanoidi | Q9D9T6 |
OMAi | TFYRKPP |
OrthoDBi | 1608431at2759 |
TreeFami | TF338040 |
Miscellaneous databases
BioGRID-ORCSi | 70060, 1 hit in 64 CRISPR screens |
PROi | PR:Q9D9T6 |
RNActi | Q9D9T6, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000026226, Expressed in testis and 75 other tissues |
Genevisiblei | Q9D9T6, MM |
Family and domain databases
InterProi | View protein in InterPro IPR026717, SPATA3 |
PANTHERi | PTHR22234, PTHR22234, 1 hit |
Pfami | View protein in Pfam PF15662, SPATA3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SPTA3_MOUSE | |
Accessioni | Q9D9T6Primary (citable) accession number: Q9D9T6 Secondary accession number(s): Q80ZS4, Q9D5L5, Q9DAF5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 10, 2003 |
Last sequence update: | October 10, 2003 | |
Last modified: | February 23, 2022 | |
This is version 106 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot