UniProtKB - Q9D9H2 (CLDN2_MOUSE)
Protein
Claudin domain-containing protein 2
Gene
Cldnd2
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Claudin domain-containing protein 2 |
Gene namesi | Name:Cldnd2 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1921526 Cldnd2 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 13 – 32 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 61 – 81 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 96 – 116 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 130 – 150 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000271021 | 1 – 167 | Claudin domain-containing protein 2Add BLAST | 167 |
Proteomic databases
PaxDbi | Q9D9H2 |
PRIDEi | Q9D9H2 |
PTM databases
PhosphoSitePlusi | Q9D9H2 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000038973 Expressed in 20 organ(s), highest expression level in testis |
ExpressionAtlasi | Q9D9H2 baseline and differential |
Genevisiblei | Q9D9H2 MM |
Family & Domainsi
Sequence similaritiesi
Belongs to the PMP-22/EMP/MP20 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG410IXHU Eukaryota ENOG41115R8 LUCA |
GeneTreei | ENSGT00950000182696 |
HOGENOMi | HOG000116021 |
InParanoidi | Q9D9H2 |
OMAi | GLWQECT |
OrthoDBi | 1579117at2759 |
PhylomeDBi | Q9D9H2 |
TreeFami | TF330587 |
Family and domain databases
InterProi | View protein in InterPro IPR004031 PMP22/EMP/MP20/Claudin |
Pfami | View protein in Pfam PF00822 PMP22_Claudin, 1 hit |
i Sequence
Sequence statusi: Complete.
Q9D9H2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGVKKSLQTG GNLLNLLSSI LTVLSTTTNY WTRQQGGHSG LWQECTHGKC
60 70 80 90 100
SNIPCQNTVA VSAACMVLAA TFSIVALGIG IRIQCREAES RRSQNTIVLL
110 120 130 140 150
FLSGLLLLIA LAVYTSKNAW KPEVFFSWSY FFGWLALPFL FIAGFCFLLA
160
DMILQSTEAI SGFPVCL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK006929 mRNA Translation: BAB24795.1 |
CCDSi | CCDS39929.1 |
RefSeqi | NP_083125.1, NM_028849.1 XP_017167841.1, XM_017312352.1 |
Genome annotation databases
Ensembli | ENSMUST00000040227; ENSMUSP00000037980; ENSMUSG00000038973 ENSMUST00000206839; ENSMUSP00000145638; ENSMUSG00000038973 |
GeneIDi | 74276 |
KEGGi | mmu:74276 |
UCSCi | uc009gms.1 mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK006929 mRNA Translation: BAB24795.1 |
CCDSi | CCDS39929.1 |
RefSeqi | NP_083125.1, NM_028849.1 XP_017167841.1, XM_017312352.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000037980 |
PTM databases
PhosphoSitePlusi | Q9D9H2 |
Proteomic databases
PaxDbi | Q9D9H2 |
PRIDEi | Q9D9H2 |
Genome annotation databases
Ensembli | ENSMUST00000040227; ENSMUSP00000037980; ENSMUSG00000038973 ENSMUST00000206839; ENSMUSP00000145638; ENSMUSG00000038973 |
GeneIDi | 74276 |
KEGGi | mmu:74276 |
UCSCi | uc009gms.1 mouse |
Organism-specific databases
CTDi | 125875 |
MGIi | MGI:1921526 Cldnd2 |
Phylogenomic databases
eggNOGi | ENOG410IXHU Eukaryota ENOG41115R8 LUCA |
GeneTreei | ENSGT00950000182696 |
HOGENOMi | HOG000116021 |
InParanoidi | Q9D9H2 |
OMAi | GLWQECT |
OrthoDBi | 1579117at2759 |
PhylomeDBi | Q9D9H2 |
TreeFami | TF330587 |
Miscellaneous databases
ChiTaRSi | Cldnd2 mouse |
PROi | PR:Q9D9H2 |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000038973 Expressed in 20 organ(s), highest expression level in testis |
ExpressionAtlasi | Q9D9H2 baseline and differential |
Genevisiblei | Q9D9H2 MM |
Family and domain databases
InterProi | View protein in InterPro IPR004031 PMP22/EMP/MP20/Claudin |
Pfami | View protein in Pfam PF00822 PMP22_Claudin, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CLDN2_MOUSE | |
Accessioni | Q9D9H2Primary (citable) accession number: Q9D9H2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 9, 2007 |
Last sequence update: | June 1, 2001 | |
Last modified: | October 16, 2019 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot