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Entry version 150 (02 Dec 2020)
Sequence version 3 (27 Jul 2011)
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Protein

Envoplakin

Gene

Evpl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processKeratinization

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6809371, Formation of the cornified envelope

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Envoplakin
Alternative name(s):
210 kDa cornified envelope precursor protein
p210
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Evpl
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:107507, Evpl

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell junction, Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000781481 – 2035EnvoplakinAdd BLAST2035

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1576PhosphoserineCombined sources1
Modified residuei1800PhosphoserineBy similarity1
Modified residuei2026PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9D952

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9D952

PeptideAtlas

More...
PeptideAtlasi
Q9D952

PRoteomics IDEntifications database

More...
PRIDEi
Q9D952

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9D952

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9D952

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000034282, Expressed in cornea and 175 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q9D952, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

May form a homodimer or a heterodimer with PPL.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
199548, 24 interactors

Protein interaction database and analysis system

More...
IntActi
Q9D952, 19 interactors

Molecular INTeraction database

More...
MINTi
Q9D952

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000037850

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9D952, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9D952

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati229 – 330SpectrinAdd BLAST102
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini413 – 470SH3PROSITE-ProRule annotationAdd BLAST58
Repeati1186 – 1227Plectin 1Add BLAST42
Repeati1679 – 1714Plectin 2Add BLAST36
Repeati1819 – 1856Plectin 3Add BLAST38
Repeati1857 – 1894Plectin 4Add BLAST38
Repeati1895 – 1932Plectin 5Add BLAST38
Repeati1933 – 1970Plectin 6Add BLAST38
Repeati1971 – 2008Plectin 7Add BLAST38

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 841Globular 1Add BLAST841
Regioni12 – 284 X 4 AA tandem repeats of K-G-S-PAdd BLAST17
Regioni842 – 1674Central fibrous rod domainAdd BLAST833
Regioni1675 – 2035Globular 2Add BLAST361

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili842 – 1664Sequence analysisAdd BLAST823

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the plakin or cytolinker family.Curated

Keywords - Domaini

Coiled coil, Repeat, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0516, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153578

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001780_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9D952

Identification of Orthologs from Complete Genome Data

More...
OMAi
GPSQINY

Database of Orthologous Groups

More...
OrthoDBi
68483at2759

TreeFam database of animal gene trees

More...
TreeFami
TF342779

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.1290.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041615, Desmoplakin_SH3
IPR030460, Envoplakin
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin

The PANTHER Classification System

More...
PANTHERi
PTHR23169, PTHR23169, 1 hit
PTHR23169:SF7, PTHR23169:SF7, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00681, Plectin, 4 hits
PF17902, SH3_10, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00250, PLEC, 8 hits
SM00150, SPEC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF75399, SSF75399, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q9D952-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFKGLSKGSQ GKGSPKGSPA KGSPKGSPNK HNRAATQELA LLISRMQANA
60 70 80 90 100
DQVERDILET QKKLQQDRQN GEQNQALQHQ QETGRNLKEA EVLLKDLFLD
110 120 130 140 150
VDKARRLKHP QAEEIEKDIK QLHERVTQEC SEYRALYEKM VLPPDVGPRV
160 170 180 190 200
DWARVLEQKQ NLVREGHYGP GMAELEQQVA EHNILQREIE AYGQQLRTLV
210 220 230 240 250
GPDANTIRNQ YRELLKAASW RRQSLGSLYT HLQGCTKQLS ALADQQGRIL
260 270 280 290 300
QQDWSDLMPD PAGVRREYEH FKQHELLAQE RSINQLEDDA DRMVELGHPA
310 320 330 340 350
IGPIQVHQEA LKMEWQNFLN LCICQESQLQ RVEDYRRFQE EADSVSQTLA
360 370 380 390 400
KLSSNLDTKY GFGTGDSSGS PTELLLQLEA EEKQLAIAER AVGDLQQRSQ
410 420 430 440 450
EVAPLPQRRN PSKQPLHVDS ICDWDSGEVQ LLRGERYTLK DNADPYTWLV
460 470 480 490 500
QGPGGETKSA PAACLCIPAP DPEAVAKASR LATELQTLKQ KLSTEKNRLK
510 520 530 540 550
AAAVEHLQPG QQAPAGSAPA DPQGQTLLSQ MTQLDGDLGQ IERQVLSWAR
560 570 580 590 600
SPLSQSSSLK DLEGRIHSCE GTAQRLQSLG AEKEAAQQEC EAFLSTKPTG
610 620 630 640 650
SAALQLPVVL NSVKNRYNDV QSLCHLYGEK AKAALGLEKQ IQEADRVIQG
660 670 680 690 700
FEAALALEGP VPEGSGALQE RVSELQRQRK ELLQQQACVL GLHRQLKATE
710 720 730 740 750
HACSALQNNF QEFCQDLPRQ QRQVRALTDR YHAVGDQLDL REKIVQDASL
760 770 780 790 800
TYQQLRNSRD NLSSWLEQLP HHRVQPSDGP SQISYKLQAQ KRLIQEILGR
810 820 830 840 850
EQDQATVSRL TRDLQEALQD YELQADTYRC SLEPALAVSA PKRLRVISLQ
860 870 880 890 900
ESIQAQEKNL AKAYTEVAAA EQQQLRQLEF AKKMLRKKEL DEDIQAIHSA
910 920 930 940 950
RQGSGSPAHA RTAESEVLKT QLEEERKRVA EVQRDLEEQR QRLLQLRTQQ
960 970 980 990 1000
PVARLEEKEV VEFYRDPQLE SNLSQAASRV EEEGKRRARL QAELEAVAQK
1010 1020 1030 1040 1050
VVHLEGKRKT MQPHLLTKEV TQIERDPGLD SQVTQLHSEM QRLRGENGVL
1060 1070 1080 1090 1100
TARLEELKDE LLALEQKEMN VKEKVVVKEV VKVEKDLEMV KAAQTLRLQI
1110 1120 1130 1140 1150
EEDAARRKGA KETVAKIQAR IKDLEQAISS VEPKVIVKEV KKVEQDPGLL
1160 1170 1180 1190 1200
KEASRLRSLL EEEKNNNVAL ARELQELQEK YRVVEKQKPK VQLQERVSEI
1210 1220 1230 1240 1250
FQVLPETEQE IRRLRAQLQE TGSKKSGVEQ EVEKLLPELE VLRAQKPVVE
1260 1270 1280 1290 1300
YKEVTQEVVR HEKNPEVLRE IDRLKAQLNE LVNTNGRSQE QLIRLQGERD
1310 1320 1330 1340 1350
EWKRERSKVE TKMVSKEVVR HEKDPVLEKE AERLRQEVRE AVQRRRATED
1360 1370 1380 1390 1400
AVYELQNKLL LLERRRPEEQ IVVQEVVVTQ KDPKLREEHS RLSRSLDEEV
1410 1420 1430 1440 1450
GRRRQLELEV RQLGARVEEE EARLSFEEDR SKKLAAEREL RQLTLKIQEL
1460 1470 1480 1490 1500
EKRPPALQEK IIMEEVVKLE KDPDLERSTE ALRRELDQEK NRVTELHREC
1510 1520 1530 1540 1550
QGLQVQVDLL QKTKSQEKTI YKEVIRVEKD PVLEGERARV WEILNRERAA
1560 1570 1580 1590 1600
RKGREEDVRS LQERIDRAEA LRRSWSREEA ELQRARDQAS QDCGRLQRQL
1610 1620 1630 1640 1650
RELEQQKQQK ARQLQEEGRL LSQKTESERQ KAAQRSQAVT QLEAAILQEK
1660 1670 1680 1690 1700
DKIYEKERTL RDLHTKVSRE ELNQETQTRE TNLSTKICIL EPETGNDMSP
1710 1720 1730 1740 1750
YEAYKRGVID RGQYLQLQEL ECDWEEVTTS SPCGEESVLL DRKSGKQYSI
1760 1770 1780 1790 1800
EAALRCRRIS KEEYHRYKDG RLPISEFALL VAGETKPSSS LSIGSIISKS
1810 1820 1830 1840 1850
PVCSPGPQST GFFSPGLSFG LTEDSFPIAG IYDTTTDNKC SIKAAVAKNM
1860 1870 1880 1890 1900
LDPITGQKLL EAQAATGGIV DLLSRERYSV HKAVERGLIE NTSTQRLLNA
1910 1920 1930 1940 1950
QKAFTGIEDP VTRKRLSVGE AIQKGWMPQE SVLPHLLVQH LTGGLIDPKR
1960 1970 1980 1990 2000
TGRIPVPQAV LCGMISEDLG QLLQDESGYE KDLTDPITKE RLSYKEAMGR
2010 2020 2030
CRKDPLSGLL LLPAMLEGYR CYRAASPTLP RSCVR
Length:2,035
Mass (Da):232,012
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i92CD7FB7DE50ECC6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti282S → N in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti437Y → C in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti466C → W in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti476A → G in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti604L → V in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti610 – 611LN → FH in CAC38864 (PubMed:10747979).Curated2
Sequence conflicti843R → E in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti852S → N in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti858K → N in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti1013P → L in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti1635R → W in CAC38864 (PubMed:10747979).Curated1
Sequence conflicti1830 – 1832GIY → EIF in CAC38864 (PubMed:10747979).Curated3
Sequence conflicti1861 – 1864EAQA → RPRQ in CAC38864 (PubMed:10747979).Curated4

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ309317 AJ319613 Genomic DNA Translation: CAC38864.2
AL669925 Genomic DNA No translation available.
AK007353 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25661.1

NCBI Reference Sequences

More...
RefSeqi
NP_079552.3, NM_025276.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000037007; ENSMUSP00000037850; ENSMUSG00000034282

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
14027

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:14027

UCSC genome browser

More...
UCSCi
uc007mkp.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ309317 AJ319613 Genomic DNA Translation: CAC38864.2
AL669925 Genomic DNA No translation available.
AK007353 mRNA No translation available.
CCDSiCCDS25661.1
RefSeqiNP_079552.3, NM_025276.3

3D structure databases

SMRiQ9D952
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi199548, 24 interactors
IntActiQ9D952, 19 interactors
MINTiQ9D952
STRINGi10090.ENSMUSP00000037850

PTM databases

iPTMnetiQ9D952
PhosphoSitePlusiQ9D952

Proteomic databases

MaxQBiQ9D952
PaxDbiQ9D952
PeptideAtlasiQ9D952
PRIDEiQ9D952

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
46112, 56 antibodies

Genome annotation databases

EnsembliENSMUST00000037007; ENSMUSP00000037850; ENSMUSG00000034282
GeneIDi14027
KEGGimmu:14027
UCSCiuc007mkp.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2125
MGIiMGI:107507, Evpl

Phylogenomic databases

eggNOGiKOG0516, Eukaryota
GeneTreeiENSGT00940000153578
HOGENOMiCLU_001780_0_0_1
InParanoidiQ9D952
OMAiGPSQINY
OrthoDBi68483at2759
TreeFamiTF342779

Enzyme and pathway databases

ReactomeiR-MMU-6809371, Formation of the cornified envelope

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
14027, 2 hits in 17 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Evpl, mouse

Protein Ontology

More...
PROi
PR:Q9D952
RNActiQ9D952, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000034282, Expressed in cornea and 175 other tissues
GenevisibleiQ9D952, MM

Family and domain databases

Gene3Di3.90.1290.10, 1 hit
InterProiView protein in InterPro
IPR041615, Desmoplakin_SH3
IPR030460, Envoplakin
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
PANTHERiPTHR23169, PTHR23169, 1 hit
PTHR23169:SF7, PTHR23169:SF7, 1 hit
PfamiView protein in Pfam
PF00681, Plectin, 4 hits
PF17902, SH3_10, 1 hit
SMARTiView protein in SMART
SM00250, PLEC, 8 hits
SM00150, SPEC, 1 hit
SUPFAMiSSF75399, SSF75399, 2 hits
PROSITEiView protein in PROSITE
PS50002, SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEVPL_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9D952
Secondary accession number(s): B1AU57
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: July 27, 2011
Last modified: December 2, 2020
This is version 150 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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