Ebna1bp2

Functionⁱ

Required for the processing of the 27S pre-rRNA.By similarity

GO - Biological processⁱ

ribosomal large subunit biogenesis
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
rRNA processing
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Ribosome biogenesis

Biological process

Ribosome biogenesis

Enzyme and pathway databases

Reactomeⁱ	R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Reactomeⁱ

R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Probable rRNA-processing protein EBP2
Gene namesⁱ	Name:Ebna1bp2 Synonyms:Ebp2
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 4

Organism-specific databases

MGIⁱ	MGI:1916322 Ebna1bp2

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000119994	1 – 306	Probable rRNA-processing protein EBP2Add BLAST		306

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	1	N-acetylmethionineBy similarity	1
Modified residueⁱ	3	PhosphothreonineBy similarity	1
Modified residueⁱ	7	PhosphoserineBy similarity	1
Modified residueⁱ	9	PhosphoserineBy similarity	1
Modified residueⁱ	11	PhosphoserineBy similarity	1
Modified residueⁱ	13	PhosphoserineBy similarity	1
Cross-linkⁱ	93	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	179	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	218	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	264	PhosphoserineBy similarity	1
Modified residueⁱ	270	PhosphoserineBy similarity	1

Keywords - PTMⁱ

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	Q9D903
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q9D903
PaxDbⁱ	Q9D903
PeptideAtlas More...PeptideAtlasⁱ	Q9D903
PRIDEⁱ	Q9D903

PTM databases

iPTMnetⁱ	Q9D903
PhosphoSitePlusⁱ	Q9D903

Miscellaneous databases

PMAP-CutDBⁱ

Q9D903

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000028729 Expressed in 289 organ(s), highest expression level in midbrain
CleanExⁱ	MM_EBNA1BP2
ExpressionAtlasⁱ	Q9D903 baseline and differential
Genevisibleⁱ	Q9D903 MM

Interactionⁱ

Subunit structureⁱ

Interacts with WDR46.By similarity

Protein-protein interaction databases

BioGridⁱ	213211, 3 interactors
CORUMⁱ	Q9D903
Database of interacting proteins More...DIPⁱ	DIP-48579N
IntActⁱ	Q9D903, 2 interactors
Molecular INTeraction database More...MINTⁱ	Q9D903
STRINGⁱ	10090.ENSMUSP00000030501

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q9D903
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	135 – 171	Sequence analysisAdd BLAST		37

Sequence similaritiesⁱ

Belongs to the EBP2 family.Curated

Keywords - Domainⁱ

Coiled coil

Phylogenomic databases

eggNOGⁱ	KOG3080 Eukaryota ENOG410YYHN LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000014984
HOGENOMⁱ	HOG000231281
HOVERGENⁱ	HBG031528
InParanoidⁱ	Q9D903
KEGG Orthology (KO) More...KOⁱ	K14823
OMAⁱ	MFHRQAQ
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HC5
PhylomeDBⁱ	Q9D903
TreeFamⁱ	TF314642

Family and domain databases

InterProⁱ	View protein in InterPro IPR008610 Ebp2
PANTHERⁱ	PTHR13028 PTHR13028, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05890 Ebp2, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q9D903-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDTPPLSESD SESDACLASD QELQDAFSRG LLKPGLNVVL EKPKKAVNDV 
        60         70         80         90        100
SGLKQCLAEF RRDLEWVERL DVTLGPVPEV SETQPTPQNQ DQKKGVNPED 
       110        120        130        140        150
DFQREMSFYR QAQAAVLAVL PRLHQLQVPT KRPTDYFAEM AKSDQQMQKI 
       160        170        180        190        200
RQKLQTKQAA MEKSEKAKQL RALRKYGKKV QTEVLQKRQR EKAHMMNAIK 
       210        220        230        240        250
KYQKGFSDKL DFLEGDQKPV ERSAKAGGKG QQMSKGPNAK RRYKNQKFGF 
       260        270        280        290        300
GGKKKGSKWN TKESYDDVSS FRAKVAHGKG SRRPGKKGAN KRPGKRARQK 

LKSKAR

Length:306

Mass (Da):34,703

Last modified:June 1, 2001 - v1

Checksum:ⁱC612FB25A47084EA

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	A2ACZ1	A2ACZ1_MOUSE		Probable rRNA-processing protein EB... Probable rRNA-processing protein EBP2	Ebna1bp2	186	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK007491 mRNA Translation: BAB25065.1 AK134732 mRNA Translation: BAE22261.1 AK167070 mRNA Translation: BAE39230.1 AK168269 mRNA Translation: BAE40215.1 AL669952 Genomic DNA No translation available. BC054723 mRNA Translation: AAH54723.1 BC062876 mRNA Translation: AAH62876.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS18555.1
NCBI Reference Sequences More...RefSeqⁱ	NP_081208.1, NM_026932.4
UniGeneⁱ	Mm.29906

Genome annotation databases

Ensemblⁱ	ENSMUST00000030501; ENSMUSP00000030501; ENSMUSG00000028729
GeneIDⁱ	69072
KEGGⁱ	mmu:69072
UCSC genome browser More...UCSCⁱ	uc008ukn.2 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q9D903	EBNA1 binding protein 2		RAT		307	UniRef90_Q9D903
probable rRNA-processing protein EBP2		MESAU		306
Putative rRNA-processing protein EBP2		CRIGR		306
Uncharacterized protein		NEOLE		304
UPI0004ED2404		NANGA		306
+5

Protein	Similar proteins		Species	Score	Length	Source
Q9D903	Probable rRNA-processing protein EBP2		XENLA		312	UniRef50_Q9D903
EBNA1 binding protein 2		RAT		307
Putative rRNA-processing protein EBP2		CRIGR		306
probable rRNA-processing protein EBP2		MESAU		306
Uncharacterized protein		NEOLE		304
+104

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK007491 mRNA Translation: BAB25065.1 AK134732 mRNA Translation: BAE22261.1 AK167070 mRNA Translation: BAE39230.1 AK168269 mRNA Translation: BAE40215.1 AL669952 Genomic DNA No translation available. BC054723 mRNA Translation: AAH54723.1 BC062876 mRNA Translation: AAH62876.1
CCDSⁱ	CCDS18555.1
RefSeqⁱ	NP_081208.1, NM_026932.4
UniGeneⁱ	Mm.29906

3D structure databases

ProteinModelPortalⁱ	Q9D903
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	213211, 3 interactors
CORUMⁱ	Q9D903
DIPⁱ	DIP-48579N
IntActⁱ	Q9D903, 2 interactors
MINTⁱ	Q9D903
STRINGⁱ	10090.ENSMUSP00000030501

PTM databases

iPTMnetⁱ	Q9D903
PhosphoSitePlusⁱ	Q9D903

Proteomic databases

EPDⁱ	Q9D903
MaxQBⁱ	Q9D903
PaxDbⁱ	Q9D903
PeptideAtlasⁱ	Q9D903
PRIDEⁱ	Q9D903

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	69072
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000030501; ENSMUSP00000030501; ENSMUSG00000028729
GeneIDⁱ	69072
KEGGⁱ	mmu:69072
UCSCⁱ	uc008ukn.2 mouse

Organism-specific databases

CTDⁱ	10969
MGIⁱ	MGI:1916322 Ebna1bp2

Phylogenomic databases

eggNOGⁱ	KOG3080 Eukaryota ENOG410YYHN LUCA
GeneTreeⁱ	ENSGT00390000014984
HOGENOMⁱ	HOG000231281
HOVERGENⁱ	HBG031528
InParanoidⁱ	Q9D903
KOⁱ	K14823
OMAⁱ	MFHRQAQ
OrthoDBⁱ	EOG091G0HC5
PhylomeDBⁱ	Q9D903
TreeFamⁱ	TF314642

Enzyme and pathway databases

Reactomeⁱ	R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Reactomeⁱ

R-MMU-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

PMAP-CutDBⁱ	Q9D903
Protein Ontology More...PROⁱ	PR:Q9D903
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000028729 Expressed in 289 organ(s), highest expression level in midbrain
CleanExⁱ	MM_EBNA1BP2
ExpressionAtlasⁱ	Q9D903 baseline and differential
Genevisibleⁱ	Q9D903 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR008610 Ebp2
PANTHERⁱ	PTHR13028 PTHR13028, 1 hit
Pfamⁱ	View protein in Pfam PF05890 Ebp2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EBP2_MOUSE
Accessionⁱ	Q9D903Primary (citable) accession number: Q9D903 Secondary accession number(s): A2ACZ0, Q3TKB5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 6, 2002
	Last sequence update:	June 1, 2001
	Last modified:	November 7, 2018
	This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9D903 (EBP2_MOUSE)

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Probable rRNA-processing protein EBP2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

Miscellaneous databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ