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Entry version 131 (07 Apr 2021)
Sequence version 2 (15 Jan 2008)
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Protein

ADP-ribosylation factor GTPase-activating protein 3

Gene

Arfgap3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity).By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri25 – 48C4-typePROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activation
Biological processER-Golgi transport, Protein transport, Transport
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6807878, COPI-mediated anterograde transport
R-MMU-6811434, COPI-dependent Golgi-to-ER retrograde traffic

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ADP-ribosylation factor GTPase-activating protein 3
Short name:
ARF GAP 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Arfgap3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1913501, Arfgap3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000741941 – 523ADP-ribosylation factor GTPase-activating protein 3Add BLAST523

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei231PhosphoserineBy similarity1
Modified residuei241PhosphoserineCombined sources1
Modified residuei270PhosphoserineBy similarity1
Modified residuei274PhosphoserineBy similarity1
Modified residuei331PhosphoserineCombined sources1
Modified residuei377PhosphoserineBy similarity1
Modified residuei435PhosphoserineBy similarity1
Modified residuei458PhosphoserineBy similarity1
Modified residuei460PhosphoserineBy similarity1
Modified residuei462PhosphoserineBy similarity1
Modified residuei464PhosphoserineBy similarity1
Modified residuei465PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q9D8S3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q9D8S3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q9D8S3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q9D8S3

PeptideAtlas

More...
PeptideAtlasi
Q9D8S3

PRoteomics IDEntifications database

More...
PRIDEi
Q9D8S3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
283255

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q9D8S3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q9D8S3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q9D8S3, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
211327, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000064893

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q9D8S3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q9D8S3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 126Arf-GAPPROSITE-ProRule annotationAdd BLAST117

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi348 – 408Ser-richAdd BLAST61

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri25 – 48C4-typePROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0706, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158466

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q9D8S3

Identification of Orthologs from Complete Genome Data

More...
OMAi
SIQDHYS

Database of Orthologous Groups

More...
OrthoDBi
1155557at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q9D8S3

TreeFam database of animal gene trees

More...
TreeFami
TF313985

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.160, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037278, ARFGAP/RecO
IPR001164, ArfGAP_dom
IPR038508, ArfGAP_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01412, ArfGap, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00405, REVINTRACTNG

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00105, ArfGap, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57863, SSF57863, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50115, ARFGAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9D8S3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDPSKQDIL AIFKRLRSVP TNKVCFDCGA KNPSWASISY GVFLCIDCSG
60 70 80 90 100
SHRSLGVHLS FIRSTELDSN WSWFQLRCMQ VGGNSNASSF FHQHGCATKD
110 120 130 140 150
TNAKYNSRAA QLYREKIKTL ATQATRRHGT DLWLDSCAAP PVSPPPKEED
160 170 180 190 200
FFASHASLEV SGAMQASAQP ESASSTPWGL ETTPEKHEGG PGQGPSVEGL
210 220 230 240 250
NTPGKAAPEV SSIIKKKPNQ AKKGLGAKKG SLGAQKLTNT SFTEIEKQAQ
260 270 280 290 300
AVDKRKEQED LARGAPKEES IVSSLRLAYK DLEISRKKDE RLNLSGQKKV
310 320 330 340 350
EAERLGMGFG SCRSGISHSV TSDMQTIEQE SPTLAKPRRK YQEDPEDSYF
360 370 380 390 400
SSSSKWSEQS SRYFDDPMEL RSSSFSSWDD GADSYWKKDS SRDPEPAMRS
410 420 430 440 450
TGSSDRPSAR RKPEYEPIGS TDEAQKKFGN VKAISSDMYF GIQAQTDFET
460 470 480 490 500
RARLERLSTS SSISSADLFD EQRKQTAGNY NLSNVLPNAP DMAQFKQGVR
510 520
SVAGKLSVFA NGVMTSIQDR YGS
Length:523
Mass (Da):57,456
Last modified:January 15, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFC093B11DB765BC3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4J0T8A0A0R4J0T8_MOUSE
ADP-ribosylation factor GTPase-acti...
Arfgap3
524Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3BQY0A0A2I3BQY0_MOUSE
ADP-ribosylation factor GTPase-acti...
Arfgap3
105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti208P → PA in BAB25220 (PubMed:16141072).Curated1
Sequence conflicti361S → SS in BAB25220 (PubMed:16141072).Curated1
Sequence conflicti361S → SS in BAC26229 (PubMed:16141072).Curated1
Sequence conflicti361S → SS in AAH04081 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK007732 mRNA Translation: BAB25220.1
AK028990 mRNA Translation: BAC26229.1
AK075788 mRNA Translation: BAC35959.1
AK169107 mRNA Translation: BAE40889.1
BC004081 mRNA Translation: AAH04081.1
BC060369 mRNA Translation: AAH60369.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS88818.1

NCBI Reference Sequences

More...
RefSeqi
NP_079721.2, NM_025445.4
XP_006521316.2, XM_006521253.3
XP_006521318.2, XM_006521255.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000226124; ENSMUSP00000154712; ENSMUSG00000054277

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
66251

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:66251

UCSC genome browser

More...
UCSCi
uc007xag.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007732 mRNA Translation: BAB25220.1
AK028990 mRNA Translation: BAC26229.1
AK075788 mRNA Translation: BAC35959.1
AK169107 mRNA Translation: BAE40889.1
BC004081 mRNA Translation: AAH04081.1
BC060369 mRNA Translation: AAH60369.1
CCDSiCCDS88818.1
RefSeqiNP_079721.2, NM_025445.4
XP_006521316.2, XM_006521253.3
XP_006521318.2, XM_006521255.3

3D structure databases

SMRiQ9D8S3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi211327, 1 interactor
STRINGi10090.ENSMUSP00000064893

PTM databases

iPTMnetiQ9D8S3
PhosphoSitePlusiQ9D8S3

Proteomic databases

EPDiQ9D8S3
jPOSTiQ9D8S3
MaxQBiQ9D8S3
PaxDbiQ9D8S3
PeptideAtlasiQ9D8S3
PRIDEiQ9D8S3
ProteomicsDBi283255

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
34963, 271 antibodies

Genome annotation databases

EnsembliENSMUST00000226124; ENSMUSP00000154712; ENSMUSG00000054277
GeneIDi66251
KEGGimmu:66251
UCSCiuc007xag.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26286
MGIiMGI:1913501, Arfgap3

Phylogenomic databases

eggNOGiKOG0706, Eukaryota
GeneTreeiENSGT00940000158466
InParanoidiQ9D8S3
OMAiSIQDHYS
OrthoDBi1155557at2759
PhylomeDBiQ9D8S3
TreeFamiTF313985

Enzyme and pathway databases

ReactomeiR-MMU-6807878, COPI-mediated anterograde transport
R-MMU-6811434, COPI-dependent Golgi-to-ER retrograde traffic

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
66251, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Arfgap3, mouse

Protein Ontology

More...
PROi
PR:Q9D8S3
RNActiQ9D8S3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

ExpressionAtlasiQ9D8S3, baseline and differential

Family and domain databases

Gene3Di3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR037278, ARFGAP/RecO
IPR001164, ArfGAP_dom
IPR038508, ArfGAP_dom_sf
PfamiView protein in Pfam
PF01412, ArfGap, 1 hit
PRINTSiPR00405, REVINTRACTNG
SMARTiView protein in SMART
SM00105, ArfGap, 1 hit
SUPFAMiSSF57863, SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50115, ARFGAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARFG3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q9D8S3
Secondary accession number(s): Q544V6, Q8BW06, Q99KN8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: January 15, 2008
Last modified: April 7, 2021
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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