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Protein

Interferon-induced 35 kDa protein homolog

Gene

Ifi35

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Interferon-induced 35 kDa protein homolog
Short name:
IFP 35
Short name:
Ifi-35
Gene namesi
Name:Ifi35
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1917360 Ifi35

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001597051 – 286Interferon-induced 35 kDa protein homologAdd BLAST286

Proteomic databases

EPDiQ9D8C4
MaxQBiQ9D8C4
PaxDbiQ9D8C4
PeptideAtlasiQ9D8C4
PRIDEiQ9D8C4

PTM databases

iPTMnetiQ9D8C4
PhosphoSitePlusiQ9D8C4

Expressioni

Inductioni

By interferon gamma.By similarity

Gene expression databases

BgeeiENSMUSG00000010358 Expressed in 244 organ(s), highest expression level in jejunum
CleanExiMM_IFI35
ExpressionAtlasiQ9D8C4 baseline and differential
GenevisibleiQ9D8C4 MM

Interactioni

Subunit structurei

Homodimer. Also interacts with B-ATF (By similarity).By similarity

Protein-protein interaction databases

BioGridi213868, 1 interactor
IntActiQ9D8C4, 4 interactors
MINTiQ9D8C4
STRINGi10090.ENSMUSP00000010502

Structurei

3D structure databases

ProteinModelPortaliQ9D8C4
SMRiQ9D8C4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni5 – 26Leucine-zipperAdd BLAST22

Sequence similaritiesi

Belongs to the NMI family.Curated

Phylogenomic databases

eggNOGiENOG410IZG7 Eukaryota
ENOG4111RNW LUCA
GeneTreeiENSGT00530000063686
HOGENOMiHOG000230968
HOVERGENiHBG052125
InParanoidiQ9D8C4
OMAiHFQKPTR
OrthoDBiEOG091G0CE6
PhylomeDBiQ9D8C4
TreeFamiTF332752

Family and domain databases

Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR034460 IFP35
IPR009909 Nmi/IFP35_dom
IPR009938 Nmi/IFP35_N
IPR012677 Nucleotide-bd_a/b_plait_sf
PANTHERiPTHR15225:SF1 PTHR15225:SF1, 1 hit
PfamiView protein in Pfam
PF07334 IFP_35_N, 1 hit
PF07292 NID, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q9D8C4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVTLQTVLY SLQEEQARLK MRLQELQQLK RERTGSPGAK IPFSVPEVPL
60 70 80 90 100
VFQGQTKQGR QVPKFVVSNL KVCCPLPEGS ALVTFEDPKV VDRLLQQKEH
110 120 130 140 150
RVNLEDCRLR VQVQPLELPV VTNIQVSSQP DNHRVLVSGF PAGLRLSEEE
160 170 180 190 200
LLDKLEIFFG KAKNGGGDVE TREMLQGTVM LGFADEEVAQ HLCQIGQFRV
210 220 230 240 250
PLDRQQVLLR VSPYVSGEIQ KAEIKFQQAP HSVLVTNIPD VMDAQELHDI
260 270 280
LEIHFQKPTR GGGEVEALTV VPSGQQGLAI FTSESS
Length:286
Mass (Da):31,876
Last modified:January 23, 2007 - v3
Checksum:i51EB0BAAD7054454
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RFB1D6RFB1_MOUSE
Interferon-induced 35 kDa protein h...
Ifi35 mCG_141023
54Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti108R → W in AAH08158 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008161 mRNA Translation: BAB25503.1
AK131884 mRNA Translation: BAE20851.1
BC008158 mRNA Translation: AAH08158.1
CCDSiCCDS25471.1
RefSeqiNP_081596.1, NM_027320.4
UniGeneiMm.45558

Genome annotation databases

EnsembliENSMUST00000010502; ENSMUSP00000010502; ENSMUSG00000010358
GeneIDi70110
KEGGimmu:70110
UCSCiuc007lox.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK008161 mRNA Translation: BAB25503.1
AK131884 mRNA Translation: BAE20851.1
BC008158 mRNA Translation: AAH08158.1
CCDSiCCDS25471.1
RefSeqiNP_081596.1, NM_027320.4
UniGeneiMm.45558

3D structure databases

ProteinModelPortaliQ9D8C4
SMRiQ9D8C4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi213868, 1 interactor
IntActiQ9D8C4, 4 interactors
MINTiQ9D8C4
STRINGi10090.ENSMUSP00000010502

PTM databases

iPTMnetiQ9D8C4
PhosphoSitePlusiQ9D8C4

Proteomic databases

EPDiQ9D8C4
MaxQBiQ9D8C4
PaxDbiQ9D8C4
PeptideAtlasiQ9D8C4
PRIDEiQ9D8C4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000010502; ENSMUSP00000010502; ENSMUSG00000010358
GeneIDi70110
KEGGimmu:70110
UCSCiuc007lox.1 mouse

Organism-specific databases

CTDi3430
MGIiMGI:1917360 Ifi35

Phylogenomic databases

eggNOGiENOG410IZG7 Eukaryota
ENOG4111RNW LUCA
GeneTreeiENSGT00530000063686
HOGENOMiHOG000230968
HOVERGENiHBG052125
InParanoidiQ9D8C4
OMAiHFQKPTR
OrthoDBiEOG091G0CE6
PhylomeDBiQ9D8C4
TreeFamiTF332752

Miscellaneous databases

PROiPR:Q9D8C4
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000010358 Expressed in 244 organ(s), highest expression level in jejunum
CleanExiMM_IFI35
ExpressionAtlasiQ9D8C4 baseline and differential
GenevisibleiQ9D8C4 MM

Family and domain databases

Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR034460 IFP35
IPR009909 Nmi/IFP35_dom
IPR009938 Nmi/IFP35_N
IPR012677 Nucleotide-bd_a/b_plait_sf
PANTHERiPTHR15225:SF1 PTHR15225:SF1, 1 hit
PfamiView protein in Pfam
PF07334 IFP_35_N, 1 hit
PF07292 NID, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiIN35_MOUSE
AccessioniPrimary (citable) accession number: Q9D8C4
Secondary accession number(s): Q3V2E7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: January 23, 2007
Last modified: September 12, 2018
This is version 110 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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