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Protein

Nucleolar protein 7

Gene

Nol7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleolar protein 7
Gene namesi
Name:Nol7
ORF Names:MNCb-1192
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:1917328 Nol7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000969381 – 254Nucleolar protein 7Add BLAST254

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki127Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei129PhosphoserineCombined sources1
Cross-linki157Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9D7Z3
PaxDbiQ9D7Z3
PeptideAtlasiQ9D7Z3
PRIDEiQ9D7Z3

PTM databases

iPTMnetiQ9D7Z3
PhosphoSitePlusiQ9D7Z3

Expressioni

Gene expression databases

BgeeiENSMUSG00000063200 Expressed in 291 organ(s), highest expression level in thymus
CleanExiMM_NOL7
ExpressionAtlasiQ9D7Z3 baseline and differential
GenevisibleiQ9D7Z3 MM

Interactioni

Protein-protein interaction databases

IntActiQ9D7Z3, 1 interactor
MINTiQ9D7Z3
STRINGi10090.ENSMUSP00000071818

Structurei

3D structure databases

ProteinModelPortaliQ9D7Z3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J0GQ Eukaryota
ENOG410YNFM LUCA
GeneTreeiENSGT00390000004118
HOGENOMiHOG000220870
HOVERGENiHBG079866
InParanoidiQ9D7Z3
OMAiKNEECEK
OrthoDBiEOG091G0WWD
PhylomeDBiQ9D7Z3
TreeFamiTF336320

Family and domain databases

InterProiView protein in InterPro
IPR039626 NOL7
IPR012579 NOL7_C
PANTHERiPTHR32337 PTHR32337, 1 hit
PfamiView protein in Pfam
PF08157 NUC129, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q9D7Z3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVQLRPRLSR IPAPAEAMVD EDQAASEEEE AEHGLLLAQP SSGAAAEPLD
60 70 80 90 100
EEEDADDEAP EELTFASAQA EAREEELRVR ASARRDKTLL KEKRKRREEL
110 120 130 140 150
FIEQKKRKLL PDAVLEQLTT ASEADIKKSP ENVKVNLKKK SEQHAKGRNS
160 170 180 190 200
KKVKVQKVQS VGQIESYMAV RLKDEDLRDS RQEAAKHFIH SCLYGSDSKR
210 220 230 240 250
TTVNKFLSLN NKRSPVKKAA AQFLTSTWGA QKQQNAKRFK KRWMAKKMKK

KTYK
Length:254
Mass (Da):28,970
Last modified:June 1, 2001 - v1
Checksum:i36DA16A5E6B97B89
GO
Isoform 2 (identifier: Q9D7Z3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     230-254: AQKQQNAKRFKKRWMAKKMKKKTYK → KIARSSVGFSSFYK

Note: No experimental confirmation available. May be due to intron retention.
Show »
Length:243
Mass (Da):27,363
Checksum:i6C5A0583789DC6BB
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VMS4A0A1Y7VMS4_MOUSE
Nucleolar protein 7
Nol7
82Annotation score:

Sequence cautioni

The sequence BAA95050 differs from that shown. Reason: Frameshift at position 104.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_014793230 – 254AQKQQ…KKTYK → KIARSSVGFSSFYK in isoform 2. 1 PublicationAdd BLAST25

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041566 mRNA Translation: BAA95050.1 Frameshift.
AK008670 mRNA Translation: BAB25823.1
AK019972 mRNA Translation: BAB31943.1
AK032963 mRNA Translation: BAC28101.1
CCDSiCCDS36644.1 [Q9D7Z3-1]
RefSeqiNP_076043.2, NM_023554.2 [Q9D7Z3-1]
UniGeneiMm.439927

Genome annotation databases

EnsembliENSMUST00000071926; ENSMUSP00000071818; ENSMUSG00000063200 [Q9D7Z3-1]
ENSMUST00000222499; ENSMUSP00000152581; ENSMUSG00000063200 [Q9D7Z3-2]
GeneIDi70078
KEGGimmu:70078
UCSCiuc007qgb.1 mouse [Q9D7Z3-2]
uc007qgc.1 mouse [Q9D7Z3-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB041566 mRNA Translation: BAA95050.1 Frameshift.
AK008670 mRNA Translation: BAB25823.1
AK019972 mRNA Translation: BAB31943.1
AK032963 mRNA Translation: BAC28101.1
CCDSiCCDS36644.1 [Q9D7Z3-1]
RefSeqiNP_076043.2, NM_023554.2 [Q9D7Z3-1]
UniGeneiMm.439927

3D structure databases

ProteinModelPortaliQ9D7Z3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9D7Z3, 1 interactor
MINTiQ9D7Z3
STRINGi10090.ENSMUSP00000071818

PTM databases

iPTMnetiQ9D7Z3
PhosphoSitePlusiQ9D7Z3

Proteomic databases

EPDiQ9D7Z3
PaxDbiQ9D7Z3
PeptideAtlasiQ9D7Z3
PRIDEiQ9D7Z3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000071926; ENSMUSP00000071818; ENSMUSG00000063200 [Q9D7Z3-1]
ENSMUST00000222499; ENSMUSP00000152581; ENSMUSG00000063200 [Q9D7Z3-2]
GeneIDi70078
KEGGimmu:70078
UCSCiuc007qgb.1 mouse [Q9D7Z3-2]
uc007qgc.1 mouse [Q9D7Z3-1]

Organism-specific databases

CTDi51406
MGIiMGI:1917328 Nol7

Phylogenomic databases

eggNOGiENOG410J0GQ Eukaryota
ENOG410YNFM LUCA
GeneTreeiENSGT00390000004118
HOGENOMiHOG000220870
HOVERGENiHBG079866
InParanoidiQ9D7Z3
OMAiKNEECEK
OrthoDBiEOG091G0WWD
PhylomeDBiQ9D7Z3
TreeFamiTF336320

Miscellaneous databases

PROiPR:Q9D7Z3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000063200 Expressed in 291 organ(s), highest expression level in thymus
CleanExiMM_NOL7
ExpressionAtlasiQ9D7Z3 baseline and differential
GenevisibleiQ9D7Z3 MM

Family and domain databases

InterProiView protein in InterPro
IPR039626 NOL7
IPR012579 NOL7_C
PANTHERiPTHR32337 PTHR32337, 1 hit
PfamiView protein in Pfam
PF08157 NUC129, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiNOL7_MOUSE
AccessioniPrimary (citable) accession number: Q9D7Z3
Secondary accession number(s): Q9CY79, Q9JJE2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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