Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Distal membrane-arm assembly complex protein 2

Gene

Dmac2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I.By similarity

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Distal membrane-arm assembly complex protein 2By similarity
Alternative name(s):
ATP synthase subunit s-like proteinCurated
Gene namesi
Name:Dmac2
Synonyms:Atp5slImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1913599 Dmac2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003186971 – 258Distal membrane-arm assembly complex protein 2Add BLAST258

Proteomic databases

EPDiQ9D7K5
MaxQBiQ9D7K5
PaxDbiQ9D7K5
PRIDEiQ9D7K5

PTM databases

PhosphoSitePlusiQ9D7K5

Expressioni

Gene expression databases

BgeeiENSMUSG00000057229 Expressed in 233 organ(s), highest expression level in heart
CleanExiMM_ATP5SL
ExpressionAtlasiQ9D7K5 baseline and differential
GenevisibleiQ9D7K5 MM

Interactioni

Subunit structurei

Interacts with incompletely assembled mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000083115

Structurei

3D structure databases

ProteinModelPortaliQ9D7K5
SMRiQ9D7K5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP synthase subunit s family.Curated

Phylogenomic databases

eggNOGiENOG410IS4E Eukaryota
ENOG4111PMF LUCA
GeneTreeiENSGT00530000063680
HOGENOMiHOG000034116
HOVERGENiHBG056046
InParanoidiQ9D7K5
OrthoDBiEOG091G07CX

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR026303 DMAC2
IPR032675 LRR_dom_sf
PANTHERiPTHR13318 PTHR13318, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q9D7K5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPRAVLHL GAREWNGRAR RIHGMSELVT PDSSREKKRT LLQFLSDHFQ
60 70 80 90 100
DIQTLREYLL QKQISKVNRE NRSFTNIQEK YGPYVAGAVF ILKQGGAVKF
110 120 130 140 150
QDKEEWIRPN NRSHFLAEIQ KFQNVPVEAV DASGCAINYQ GLSNLLPLKE
160 170 180 190 200
LRSLSLQRCP NLDDWCLSRL YLLAGSLQEL SLAGCPRISE RGLACLHHLQ
210 220 230 240 250
NLRRLDISDL PAVSHPGLTQ ILVEEMLPHC EVLGADWAQN LKLEPDKQPP

DTSTPLSS
Length:258
Mass (Da):29,179
Last modified:June 1, 2001 - v1
Checksum:iC43E4A5C986CE7F9
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8CA44Q8CA44_MOUSE
Distal membrane-arm assembly comple...
Dmac2 2310004L02Rik, Atp5sl, mCG_7653
257Annotation score:
A0A0U1RNX2A0A0U1RNX2_MOUSE
Distal membrane-arm assembly comple...
Dmac2 Atp5sl
94Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009150 mRNA Translation: BAB26107.1
CCDSiCCDS71917.1
RefSeqiNP_001277416.1, NM_001290487.1
UniGeneiMm.159956

Genome annotation databases

EnsembliENSMUST00000077338; ENSMUSP00000076563; ENSMUSG00000057229
GeneIDi66349
KEGGimmu:66349
UCSCiuc009fte.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK009150 mRNA Translation: BAB26107.1
CCDSiCCDS71917.1
RefSeqiNP_001277416.1, NM_001290487.1
UniGeneiMm.159956

3D structure databases

ProteinModelPortaliQ9D7K5
SMRiQ9D7K5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000083115

PTM databases

PhosphoSitePlusiQ9D7K5

Proteomic databases

EPDiQ9D7K5
MaxQBiQ9D7K5
PaxDbiQ9D7K5
PRIDEiQ9D7K5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000077338; ENSMUSP00000076563; ENSMUSG00000057229
GeneIDi66349
KEGGimmu:66349
UCSCiuc009fte.2 mouse

Organism-specific databases

CTDi55101
MGIiMGI:1913599 Dmac2

Phylogenomic databases

eggNOGiENOG410IS4E Eukaryota
ENOG4111PMF LUCA
GeneTreeiENSGT00530000063680
HOGENOMiHOG000034116
HOVERGENiHBG056046
InParanoidiQ9D7K5
OrthoDBiEOG091G07CX

Miscellaneous databases

PROiPR:Q9D7K5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000057229 Expressed in 233 organ(s), highest expression level in heart
CleanExiMM_ATP5SL
ExpressionAtlasiQ9D7K5 baseline and differential
GenevisibleiQ9D7K5 MM

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR026303 DMAC2
IPR032675 LRR_dom_sf
PANTHERiPTHR13318 PTHR13318, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDMAC2_MOUSE
AccessioniPrimary (citable) accession number: Q9D7K5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: June 1, 2001
Last modified: November 7, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again